GL1X · GenesisL1 explorer

MolNFT v1 · #501303 · protein

AlphaFold monomer V2.0 prediction for xanthine-guanine phosphoribosyltransferase (Q8ZC05)

Q8ZC05: “AlphaFold monomer V2.0 prediction for xanthine-guanine phosphoribosyltransferase (Q8ZC05)”. 1 pocket (best druggability 0.55). MolNFT v1 #501303 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q8ZC05
Type
protein
Length
152 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xf87a97E0A4bB354D834857B14296240B167cbe70
Molecule
Xanthine-guanine phosphoribosyltransferase
UniProt
Q8ZC05
Pockets
1 · best druggability 0.55

Structure

1 distinct chain · 28% helix, 35% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AXanthine-guanine phosphoribosyltransferaseprotein15228% helix, 35% strandQ8ZC05

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12990.550.7629empty

Compared structures

  • 5XTK · Crystal structure of xanthine-guanine phosphoribosyltransferase from yersinia pestis · an experimental structure of the same protein · chain A against A, TM-score 0.96
  • 6KQC · Crystal structure of E136F mutant of Xanthine-guanine phosphoribosyltransferase from… · an experimental structure of the same protein · chain A against A, TM-score 0.90
  • 6KQC · Crystal structure of E136F mutant of xanthine-guanine phosphoribosyltransferase from… · an experimental structure of the same protein · chain A against A, TM-score 0.90
  • 6KP5 · Crystal structure of xanthine-guanine phosphoribosyltransferase (xgprt) from yersinia… · an experimental structure of the same protein · chain A against A, TM-score 0.90

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