UniProt Q8WUM0
Nuclear pore complex protein Nup133 (Q8WUM0)
Nuclear pore complex protein Nup133 (UniProt Q8WUM0): 13 experimental structures and 1 predicted model on GenesisL1, 45 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8WUM0
- Protein
- Nuclear pore complex protein Nup133
- Experimental structures
- 13
- Predicted models
- 1
- Pockets
- 45 · 12 records with a druggable one
Structures
14 records of Q8WUM0 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1XKS | The crystal structure of the N-terminal domain of Nup133 reveals a beta-propeller fold common to… | x-ray diffraction | A | — | 1 (best 0.76) |
| 1XKS | The crystal structure of the N-terminal domain of NUP133 reveals a beta-propeller fold common to… | x-ray diffraction | A | — | 1 (best 0.76) |
| 3CQC | Nucleoporin Nup107/Nup133 interaction complex | x-ray diffraction | B | — | 4 (best 0.64) |
| 3CQC | Nucleoporin NUP107/NUP133 interaction complex | x-ray diffraction | B | — | 4 (best 0.64) |
| 3CQG | Nucleoporin Nup107/Nup133 interaction complex, delta finger mutant | x-ray diffraction | B | — | 2 (best 0.63) |
| 3CQG | Nucleoporin NUP107/NUP133 interaction complex, delta finger mutant | x-ray diffraction | B | — | 2 (best 0.63) |
| 3I4R | Nup107(aa658-925)/Nup133(aa517-1156) complex, H.sapiens | x-ray diffraction | B | — | 6 (best 0.78) |
| 3I4R | NUP107(AA658-925)/NUP133(AA517-1156) complex, H.SAPIENS | x-ray diffraction | B | — | 6 (best 0.78) |
| 5A9Q | Human nuclear pore complex | electron microscopy | 3, C, L, U | — | — |
| 5A9Q | Human nuclear pore complex | electron microscopy | 3, C, L, U | — | — |
| 7PEQ | Model of the outer rings of the human nuclear pore complex | electron microscopy | AC, BC, CC, DC | — | 2 (best 0.76) |
| 7R5J | Human nuclear pore complex (dilated) | electron microscopy | K0, K1, K2, K3 | — | 2 (best 0.81) |
| 7R5K | Human nuclear pore complex (constricted) | electron microscopy | K0, K1, K2, K3 | — | 2 (best 0.81) |
| Q8WUM0 | AlphaFold monomer V2.0 prediction for nuclear pore complex protein NUP133 (Q8WUM0) | predicted | A | — | 13 (best 0.81) |
Experiment against prediction
- 1XKS chain A against the predicted model Q8WUM0: TM-score 1.00, RMSD 0.33 Å
- 1XKS chain A against the predicted model Q8WUM0: TM-score 1.00, RMSD 0.33 Å
- 3CQC chain B against the predicted model Q8WUM0: TM-score 0.97, RMSD 0.98 Å
- 3CQC chain B against the predicted model Q8WUM0: TM-score 0.97, RMSD 0.98 Å
- 3CQG chain B against the predicted model Q8WUM0: TM-score 0.96, RMSD 1.09 Å
- 3CQG chain B against the predicted model Q8WUM0: TM-score 0.96, RMSD 1.09 Å
- 7PEQ chain AC against the predicted model Q8WUM0: TM-score 0.92, RMSD 2.57 Å
- 7PEQ chain BC against the predicted model Q8WUM0: TM-score 0.92, RMSD 2.57 Å
- 7PEQ chain DC against the predicted model Q8WUM0: TM-score 0.92, RMSD 2.57 Å
- 7PEQ chain CC against the predicted model Q8WUM0: TM-score 0.92, RMSD 2.57 Å
Elsewhere
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