MolNFT v1 · #27472 · protein

The crystal structure of the N-terminal domain of NUP133 reveals a beta-propeller fold common to several nucleoporins

1XKS · Nuclear pore complex protein NUP133: “The crystal structure of the N-terminal domain of NUP133 reveals a beta-propeller fold common to several…”. X-ray diffraction, 1 pocket (best druggability 0.76). MolNFT v1 #27472 on GenesisL1…

PDB: 1XKS
Type: protein
Length: 374 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nuclear pore complex protein NUP133
UniProt: Q8WUM0
Pockets: 1 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 11% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nuclear pore complex protein NUP133	protein	374	11% helix, 46% strand	Q8WUM0

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1125	0.76	0.79	85	empty

Compared structures

1XKS · The crystal structure of the N-terminal domain of Nup133 reveals a beta-propeller fold… · the same entry in another collection · chain A against A, TM-score 1.00
Q8WUM0 · AlphaFold monomer V2.0 prediction for nuclear pore complex protein NUP133 (Q8WUM0) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8WUM0
Elsewhere: RCSB PDB 1XKS · PDBe 1XKS · UniProt Q8WUM0

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