UniProt Q8WSF8
Soluble acetylcholine receptor (Q8WSF8)
Soluble acetylcholine receptor (UniProt Q8WSF8): 143 experimental structures on GenesisL1, 23 ligands bound, 52 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q8WSF8
- Protein
- Soluble acetylcholine receptor
- Experimental structures
- 143
- Predicted models
- 0
- Ligands
- 23
- Pockets
- 52 · 3 records with a druggable one
Structures
143 records of Q8WSF8 in the MolNFT archive: 143 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2BR7 | Crystal Structure of Acetylcholine-binding Protein (AChBP) from Aplysia californica in complex with… | x-ray diffraction | A, B, C, D, E | — | — |
| 2BR7 | Crystal structure of acetylcholine-binding protein (achbp) from aplysia californica in complex with… | x-ray diffraction | A, B, C, D, E | — | — |
| 2BR8 | Crystal Structure of Acetylcholine-binding Protein (AChBP) from Aplysia californica in complex with… | x-ray diffraction | A, B, C, D, E | — | — |
| 2BR8 | Crystal structure of acetylcholine-binding protein (achbp) from aplysia californica in complex with… | x-ray diffraction | A, B, C, D, E | — | — |
| 2BYN | Crystal structure of apo AChBP from Aplysia californica | x-ray diffraction | A, B, C, D, E | — | — |
| 2BYN | Crystal structure of apo achbp from aplysia californica | x-ray diffraction | A, B, C, D, E | — | — |
| 2BYP | Crystal structure of Aplysia californica AChBP in complex with alpha- conotoxin ImI | x-ray diffraction | A, B, C, D, E | — | — |
| 2BYP | Crystal structure of aplysia californica achbp in complex with alpha- conotoxin imi | x-ray diffraction | A, B, C, D, E | — | — |
| 2BYQ | Crystal structure of Aplysia californica AChBP in complex with epibatidine | x-ray diffraction | A, B, C, D, E | — | — |
| 2BYQ | Crystal structure of aplysia californica achbp in complex with epibatidine | x-ray diffraction | A, B, C, D, E | — | — |
| 2BYR | CRYSTAL STRUCTURE OF ACHBP FROM APLYSIA CALIFORNICA in complex with methyllycaconitine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2BYR | Crystal structure of achbp from aplysia californica in complex with methyllycaconitine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2BYS | CRYSTAL STRUCTURE OF ACHBP FROM APLYSIA CALIFORNICA IN complex with lobeline | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2BYS | Crystal structure of achbp from aplysia californica in complex with lobeline | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2C9T | Crystal Structure Of Acetylcholine Binding Protein (AChBP) From Aplysia Californica In Complex With… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2C9T | Crystal structure of acetylcholine binding protein (achbp) from aplysia californica in complex with… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2PGZ | Crystal structure of Cocaine bound to an ACh-Binding Protein | x-ray diffraction | A, B, C, D, E | — | — |
| 2PGZ | Crystal structure of cocaine bound to an ach-binding protein | x-ray diffraction | A, B, C, D, E | — | — |
| 2PH9 | Galanthamine bound to an ACh-binding Protein | x-ray diffraction | A, B, C, D, E | — | — |
| 2PH9 | Galanthamine bound to an ach-binding protein | x-ray diffraction | A, B, C, D, E | — | — |
| 2UZ6 | AChBP-targeted a-conotoxin correlates distinct binding orientations with nAChR subtype selectivity. | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2UZ6 | Achbp-targeted a-conotoxin correlates distinct binding orientations with nachr subtype selectivity. | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2W8F | Aplysia californica AChBP bound to in silico compound 31 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2W8F | Aplysia californica achbp bound to in silico compound 31 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2W8G | Aplysia californica AChBP bound to in silico compound 35 | x-ray diffraction | A, B, C, D, E | — | — |
| 2W8G | Aplysia californica achbp bound to in silico compound 35 | x-ray diffraction | A, B, C, D, E | — | — |
| 2WN9 | Crystal structure of Aplysia ACHBP in complex with 4-0H-DMXBA | x-ray diffraction | A, B, C, D, E | — | — |
| 2WN9 | Crystal structure of aplysia achbp in complex with 4-0H-dmxba | x-ray diffraction | A, B, C, D, E | — | — |
| 2WNC | Crystal structure of Aplysia ACHBP in complex with tropisetron | x-ray diffraction | A, B, C, D, E | — | — |
| 2WNC | Crystal structure of aplysia achbp in complex with tropisetron | x-ray diffraction | A, B, C, D, E | — | — |
| 2WNJ | Crystal structure of aplysia achbp in complex with dmxba | x-ray diffraction | A, B, C, D, E | — | — |
| 2WNJ | Crystal structure of aplysia achbp in complex with dmxba | x-ray diffraction | A, B, C, D, E | — | — |
| 2WNL | Crystal structure of aplysia achbp in complex with anabaseine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2WNL | Crystal structure of aplysia achbp in complex with anabaseine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2WZY | Crystal structure of A-AChBP in complex with 13-desmethyl spirolide C | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2WZY | Crystal structure of a-achbp in complex with 13-desmethyl spirolide C | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2X00 | Crystal structure of a-achbp in complex with gymnodimine a | x-ray diffraction | A, B, C, D, E | — | — |
| 2X00 | Crystal structure of a-achbp in complex with gymnodimine a | x-ray diffraction | A, B, C, D, E | — | — |
| 2XNT | Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2XNT | Acetylcholine binding protein (achbp) as template for hierarchical in silico screening procedures… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2XNU | Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures… | x-ray diffraction | A, B, C, D, E | — | — |
| 2XNU | Acetylcholine binding protein (achbp) as template for hierarchical in silico screening procedures… | x-ray diffraction | A, B, C, D, E | — | — |
| 2XNV | Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2XNV | Acetylcholine binding protein (achbp) as template for hierarchical in silico screening procedures… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2XYS | Crystal structure of Aplysia californica AChBP in complex with strychnine | x-ray diffraction | A, B, C, D, E | — | — |
| 2XYS | Crystal structure of aplysia californica achbp in complex with strychnine | x-ray diffraction | A, B, C, D, E | — | — |
| 2XYT | Crystal structure of Aplysia californica AChBP in complex with d- tubocurarine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2XYT | Crystal structure of aplysia californica achbp in complex with D-tubocurarine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2XZ5 | MMTS-modified Y53C mutant of Aplysia AChBP in complex with acetylcholine | x-ray diffraction | A, B, C, D, E | — | — |
| 2XZ5 | Mmts-modified Y53C mutant of aplysia achbp in complex with acetylcholine | x-ray diffraction | A, B, C, D, E | — | — |
| 2XZ6 | MTSET-modified Y53C mutant of Aplysia AChBP | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2XZ6 | Mtset-modified Y53C mutant of aplysia achbp | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2Y54 | Fragment growing induces conformational changes in acetylcholine- binding protein: A structural and… | x-ray diffraction | A, B, C, D, E | — | — |
| 2Y54 | Fragment growing induces conformational changes in acetylcholine- binding protein: a structural and… | x-ray diffraction | A, B, C, D, E | — | — |
| 2Y56 | Fragment growing induces conformational changes in acetylcholine- binding protein: A structural and… | x-ray diffraction | A, B, C, D, E | — | — |
| 2Y56 | Fragment growing induces conformational changes in acetylcholine- binding protein: a structural and… | x-ray diffraction | A, B, C, D, E | — | — |
| 2Y57 | Fragment growing induces conformational changes in acetylcholine- binding protein: A structural and… | x-ray diffraction | A, B, C, D, E | — | — |
| 2Y57 | Fragment growing induces conformational changes in acetylcholine- binding protein: a structural and… | x-ray diffraction | A, B, C, D, E | — | — |
| 2Y58 | Fragment growing induces conformational changes in acetylcholine- binding protein: A structural and… | x-ray diffraction | A, B, C, D, E | — | — |
| 2Y58 | Fragment growing induces conformational changes in acetylcholine- binding protein: a structural and… | x-ray diffraction | A, B, C, D, E | — | — |
83 records more on the page itself.
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 20 records
- SY9 · Strychnine · in 5 records
- PO4 · Phosphate ion · in 4 records
- 7KO · 6-chloro-N~4~,N~4~-bis[(pyridin-3-yl)methyl]pyrimidine-2,4-diamine · in 3 records
- NH2 · Amino group · in 3 records
- SO4 · Sulfate ion · in 3 records
- 7A9 · palonosetron · in 2 records
- 7LB · (E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine · in 2 records
- CL · Chloride ion · in 2 records
- JCW · 2-[5-[(1~{R},2~{R},4~{S})-7-azabicyclo[2.2.1]heptan-2-yl]-2-fluoranyl-pyridin-3-yl]pyridine-4-carboxamide · in 2 records
- NCT · (S)-3-(1-methylpyrrolidin-2-yl)pyridine · in 2 records
- 4P0 · 1-[(1R,6R)-9-azabicyclo[4.2.1]non-2-en-2-yl]ethanone · in 1 record
- 6S7 · 2-((5-(3,7-diazabicyclo[3.3.1]nonan-3-yl)pyridin-3-yl) oxy)-N,N-dimethylethanamine · in 1 record
- 74S · 9-[[1-[8-methyl-8-(2-phenylethyl)-8-azoniabicyclo[3.2.1]octan-3-yl]triazol-4-yl]methyl]carbazole · in 1 record
- C5E · (1R,5S)-1,2,3,4,5,6-hexahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one · in 1 record
- H92 · 4-[5-[(1~{R},2~{R},4~{S})-7-azabicyclo[2.2.1]heptan-2-yl]-2-fluoranyl-pyridin-3-yl]benzamide · in 1 record
- J94 · (5S)-6,6-dimethyl-5-[(6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl]-5,6,7,8-tetrahydro[1, 3]dioxolo[4,5-g]isoquinolin-6-ium · in 1 record
- JC8 · 6-[5-[(1~{R},2~{R},4~{S})-7-azabicyclo[2.2.1]heptan-2-yl]-2-fluoranyl-pyridin-3-yl]pyridine-3-carboxamide · in 1 record
- LDQ · Hosieine · in 1 record
- MG · Magnesium ion · in 1 record
- NA · Sodium ion · in 1 record
- OXL · Oxalate ion · in 1 record
- TKT · (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate · in 1 record
Experiment against prediction
- 4ZJS chain E against the predicted model P02708: TM-score 0.93, RMSD 1.81 Å
- 4ZJS chain E against the predicted model P02708: TM-score 0.93, RMSD 1.81 Å
- 4ZJS chain D against the predicted model P02708: TM-score 0.93, RMSD 1.83 Å
- 4ZJS chain D against the predicted model P02708: TM-score 0.93, RMSD 1.83 Å
- 4ZJS chain C against the predicted model P02708: TM-score 0.93, RMSD 1.88 Å
- 4ZJS chain C against the predicted model P02708: TM-score 0.93, RMSD 1.88 Å
- 4ZJS chain B against the predicted model P02708: TM-score 0.93, RMSD 1.83 Å
- 4ZJS chain B against the predicted model P02708: TM-score 0.93, RMSD 1.83 Å
- 4ZJS chain A against the predicted model P02708: TM-score 0.93, RMSD 1.93 Å
- 4ZJS chain A against the predicted model P02708: TM-score 0.93, RMSD 1.93 Å
Elsewhere
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