UniProt Q8WS26
Farnesyl diphosphate synthase (Q8WS26)
Farnesyl diphosphate synthase (UniProt Q8WS26): 87 experimental structures on GenesisL1, 55 ligands bound, 27 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q8WS26
- Protein
- Farnesyl diphosphate synthase
- Experimental structures
- 87
- Predicted models
- 0
- Ligands
- 55
- Pockets
- 27 · 13 records with a druggable one
Structures
87 records of Q8WS26 in the MolNFT archive: 87 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1YHK | Trypanosoma cruzi farnesyl diphosphate synthase | x-ray diffraction | A | — | — |
| 1YHK | Trypanosoma cruzi farnesyl diphosphate synthase | x-ray diffraction | A | — | — |
| 1YHL | Structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with risedronate, dmapp… | x-ray diffraction | A | — | — |
| 1YHL | Structure of the complex of trypanosoma cruzi farnesyl diphosphate synthase with risedronate, dmapp… | x-ray diffraction | A | — | — |
| 1YHM | Structure of the complex of Trypanosoma cruzi farnesyl disphosphate synthase with alendronate… | x-ray diffraction | A, B, C | — | — |
| 1YHM | Structure of the complex of trypanosoma cruzi farnesyl disphosphate synthase with alendronate… | x-ray diffraction | A, B, C | — | — |
| 5QPD | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000293A | x-ray diffraction | A | SO4, ZN, LT7 | — |
| 5QPE | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000295A | x-ray diffraction | A | SO4, ZN, AWG | — |
| 5QPF | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000478a | x-ray diffraction | A | SO4, ZN, AWM | — |
| 5QPF | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000478A | x-ray diffraction | A | SO4, ZN, AWM | — |
| 5QPG | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000291A | x-ray diffraction | A | SO4, ZN, AWV | — |
| 5QPH | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000315a | x-ray diffraction | A | SO4, ZN, LUS | — |
| 5QPH | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000315A | x-ray diffraction | A | SO4, ZN, LUS | — |
| 5QPI | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000554A | x-ray diffraction | A | SO4, ZN, GQM | — |
| 5QPJ | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000465a | x-ray diffraction | A | SO4, ZN, JGJ | — |
| 5QPJ | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000465A | x-ray diffraction | A | SO4, ZN, JGJ | — |
| 5QPK | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000586A | x-ray diffraction | A | SO4, ZN, LUY | — |
| 5QPL | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000464A | x-ray diffraction | A | SO4, ZN, M0J | — |
| 5QPM | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000500A | x-ray diffraction | A | SO4, ZN, LV1 | — |
| 5QPN | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000576a | x-ray diffraction | A | SO4, ZN, LDV | — |
| 5QPN | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000576A | x-ray diffraction | A | SO4, ZN, LDV | — |
| 5QPO | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000574a | x-ray diffraction | A | SO4, GQP | — |
| 5QPO | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000574A | x-ray diffraction | A | SO4, GQP | — |
| 5QPP | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000512a | x-ray diffraction | A | SO4, ZN, LV4 | 3 (best 0.77) |
| 5QPP | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000512A | x-ray diffraction | A | SO4, ZN, LV4 | — |
| 5QPQ | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000631A | x-ray diffraction | A | SO4, ZN, LV7 | — |
| 5QPR | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with XST00001145B | x-ray diffraction | A | SO4, ZN, LVD | — |
| 5QPS | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000644A | x-ray diffraction | A | SO4, ZN, LVP | — |
| 5QPT | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000642A | x-ray diffraction | A | SO4, ZN, LVV | — |
| 5QPU | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000733a | x-ray diffraction | A | SO4, ZN, JHS | — |
| 5QPU | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000733A | x-ray diffraction | A | SO4, ZN, JHS | — |
| 5QPV | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000416a | x-ray diffraction | A | SO4, ZN, LWA | — |
| 5QPV | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000416A | x-ray diffraction | A | SO4, ZN, LWA | — |
| 5QPW | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000632A | x-ray diffraction | A | SO4, ZN, JH7 | — |
| 5QPX | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000534a | x-ray diffraction | A | SO4, ZN, LWD | — |
| 5QPX | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000534A | x-ray diffraction | A | SO4, ZN, LWD | — |
| 5QPY | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000449a | x-ray diffraction | A | SO4, ZN, JH1 | — |
| 5QPY | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000449A | x-ray diffraction | A | SO4, ZN, JH1 | — |
| 5QPZ | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000524a | x-ray diffraction | A | SO4, ZN, AYV | 2 (best 0.79) |
| 5QPZ | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000524A | x-ray diffraction | A | SO4, ZN, AYV | — |
| 5QQ0 | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with XST00000046b | x-ray diffraction | A | SO4, ZN, LWV | 2 (best 0.79) |
| 5QQ0 | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with XST00000046B | x-ray diffraction | A | SO4, ZN, LWV | — |
| 5QQ1 | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000699A | x-ray diffraction | A | SO4, ZN, LX4 | — |
| 5QQ2 | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000693a | x-ray diffraction | A | SO4, ZN, MJ4 | 3 (best 0.78) |
| 5QQ2 | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000693A | x-ray diffraction | A | SO4, ZN, MJ4 | — |
| 5QQ3 | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000672A | x-ray diffraction | A | SO4, ZN, LXA | — |
| 5QQ4 | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000276a | x-ray diffraction | A | SO4, ZN, LX7 | — |
| 5QQ4 | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOPL000276A | x-ray diffraction | A | SO4, ZN, LX7 | — |
| 5QQ5 | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with PKTTA024495b | x-ray diffraction | A | SO4, ZN, JJM | — |
| 5QQ5 | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with PKTTA024495B | x-ray diffraction | A | SO4, ZN, JJM | — |
| 5QQ6 | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOOA000530a | x-ray diffraction | A | SO4, ZN, LXJ | — |
| 5QQ6 | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOOA000530A | x-ray diffraction | A | SO4, ZN, LXJ | — |
| 5QQ7 | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOOA000562a | x-ray diffraction | A | SO4, ZN, LXM | — |
| 5QQ7 | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOOA000562A | x-ray diffraction | A | SO4, ZN, LXM | — |
| 5QQ8 | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOOA000563A | x-ray diffraction | A | SO4, ZN, LXS | — |
| 5QQ9 | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOOA000567A | x-ray diffraction | A | SO4, ZN, M0D | — |
| 5QQA | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOOA000648A | x-ray diffraction | A | SO4, ZN, LZV | — |
| 5QQB | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOOA000676a | x-ray diffraction | A | SO4, ZN, LZY | — |
| 5QQB | Pandda analysis group deposition -- crystal structure of T. cruzi fpps in complex with FMOOA000676A | x-ray diffraction | A | SO4, ZN, LZY | — |
| 5QQC | Crystal structure of T. cruzi fpps after initial refinement with no ligand modelled (structure $N) | x-ray diffraction | A | SO4, MG | — |
27 records more on the page itself.
Ligands
- SO4 · Sulfate ion · in 80 records
- ZN · Zinc ion · in 72 records
- MN · Manganese (II) ion · in 3 records
- AWM · 2-(4-methylpiperazin-1-yl)-1,3-benzothiazole · in 2 records
- AYV · 1-[2-methyl-1,3-bis(oxidanyl)propan-2-yl]-3-phenyl-urea · in 2 records
- GO1 · 3-(carboxymethyl)-5,7-dichloro-1H-indole-2-carboxylic acid · in 2 records
- GQP · 1-[(4-fluorophenyl)methyl]benzimidazole · in 2 records
- JGJ · 2-methoxy-N-[(1R)-1-phenylethyl]acetamide · in 2 records
- JH1 · 1-ethyl-N-[(4-fluorophenyl)methyl]-1H-pyrazole-4-carboxamide · in 2 records
- JHS · N-[(4-phenyloxan-4-yl)methyl]acetamide · in 2 records
- JJM · 1-methyl-N-(3-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine · in 2 records
- JMT · 3-[[4-(1,3-benzothiazol-2-yl)piperazin-1-yl]methyl]-1~{H}-indol-5-ol · in 2 records
- JNE · 6-methyl-~{N}-(phenylmethyl)pyridin-2-amine · in 2 records
- LDV · 3-[(4-methylpiperidin-1-yl)methyl]-1H-indole · in 2 records
- LDW · 5-(4-fluoranylphenoxy)pyridin-2-amine · in 2 records
- LUS · 4-(4-ethylcyclohexyl)morpholine · in 2 records
- LV4 · 1-[2-(trifluoromethyloxy)phenyl]thiourea · in 2 records
- LWA · (2~{S})-~{N}-(4-aminocarbonylphenyl)oxolane-2-carboxamide · in 2 records
- LWD · ~{N}-quinolin-6-ylbenzamide · in 2 records
- LWV · 2-morpholin-4-ylaniline · in 2 records
- LX7 · 1-[4-(trifluoromethyloxy)phenyl]thiourea · in 2 records
- LXJ · (3~{a}~{S},8~{a}~{S})-6-(phenylcarbonyl)-2,3,3~{a},7,8,8~{a}-hexahydropyrrolo[3,4-d]azepin-1-one · in 2 records
- LXM · [(3~{S},3~{a}~{S},8~{b}~{S})-3-(hydroxymethyl)-2,3,3~{a},8~{b}-tetrahydro-[1]benzofuro[3,2-b]pyrrol-1-yl]-phenyl-methanone · in 2 records
- LZY · 8-fluoranyl-5-methyl-1,2,3,6-tetrahydro-1,5-benzodiazocin-4-one · in 2 records
- MJ4 · (2R)-1-{[(5-methylthiophen-2-yl)methyl]amino}propan-2-ol · in 2 records
- ZCQ · 3-nitrophenol · in 2 records
- 3N2 · (5-chloro-1-benzothiophen-3-yl)acetic acid · in 1 record
- 47Y · 3-[(4E)-4-imino-5,6-dimethylfuro[2,3-d]pyrimidin-3(4H)-yl]-N,N-dimethylpropan-1-amine · in 1 record
- 4NC · 4-nitrocatechol · in 1 record
- AWG · ~{N}2-(1~{H}-benzimidazol-2-yl)benzene-1,2-diamine · in 1 record
Elsewhere
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