UniProt Q8NAC3
Interleukin-17 receptor C (Q8NAC3)
Interleukin-17 receptor C (UniProt Q8NAC3): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 25 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8NAC3
- Protein
- Interleukin-17 receptor C
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 25 · 4 records with a druggable one
Structures
9 records of Q8NAC3 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6HG4 | Crystal Structure of the human IL-17RC ECD in complex with human IL-17F | x-ray diffraction | B | — | 5 (best 0.72) |
| 6HG4 | Crystal structure of the human il-17RC ecd in complex with human il- 17F | x-ray diffraction | B | — | — |
| 6HG9 | Crystal Structure of the human IL-17RC ECD in complex with human IL-17F, Crystal form II | x-ray diffraction | B | — | 3 (best 0.72) |
| 6HG9 | Crystal structure of the human il-17RC ecd in complex with human il- 17F, crystal form II | x-ray diffraction | B | — | — |
| 6HGA | Crystal structure of the human il-17RC D2-D3-D4 domains in complex with an anti-app tag Fab | x-ray diffraction | B | NAG | — |
| 7UWN | Structure of the IL-17A-IL-17RA-IL-17RC ternary complex | electron microscopy | G | NAG | 9 (best 0.72) |
| 7UWN | Structure of the il-17A-il-17RA-il-17RC ternary complex | electron microscopy | G | NAG | — |
| 7ZAN | Crystal Structure of human IL-17A in complex with IL-17RA and IL-17RC | x-ray diffraction | D | NAG | 8 (best 0.73) |
| Q8NAC3 | AlphaFold monomer V2.0 prediction for interleukin-17 receptor C (Q8NAC3) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
Experiment against prediction
- 6HG4 chain B against the predicted model Q8NAC3: TM-score 0.95, RMSD 1.91 Å
- 6HG4 chain B against the predicted model Q8NAC3: TM-score 0.95, RMSD 1.91 Å
- 6HG9 chain B against the predicted model Q8NAC3: TM-score 0.92, RMSD 2.31 Å
- 6HG9 chain B against the predicted model Q8NAC3: TM-score 0.92, RMSD 2.31 Å
- 6HGA chain B against the predicted model Q8NAC3: TM-score 0.91, RMSD 2.23 Å
- 7UWN chain G against the predicted model Q8NAC3: TM-score 0.91, RMSD 2.40 Å
- 7UWN chain G against the predicted model Q8NAC3: TM-score 0.91, RMSD 2.40 Å
- 7ZAN chain D against the predicted model Q8NAC3: TM-score 0.90, RMSD 2.79 Å
Elsewhere
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