UniProt Q8N4J0
Carnosine N-methyltransferase (Q8N4J0)
Carnosine N-methyltransferase (UniProt Q8N4J0), EC 2.1.1.22: 6 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q8N4J0
- Protein
- Carnosine N-methyltransferase
- EC
- 2.1.1.22
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 10 · 2 records with a druggable one
Structures
7 records of Q8N4J0 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5YF0 | Crystal structure of CARNMT1 bound to SAM | x-ray diffraction | A, B | SAM, CA | 5 (best 0.77) |
| 5YF0 | Crystal structure of CARNMT1 bound to SAM | x-ray diffraction | A, B | CA | — |
| 5YF1 | Crystal structure of CARNMT1 bound to carnosine and SFG | x-ray diffraction | A, B | SFG, 8V0, CA | 5 (best 0.75) |
| 5YF1 | Crystal structure of CARNMT1 bound to carnosine and sfg | x-ray diffraction | A, B | 8V0, CA | — |
| 5YF2 | Crystal structure of CARNMT1 bound to anserine and SAH | x-ray diffraction | A, B | 8V3, CA | — |
| 5YF2 | Crystal structure of CARNMT1 bound to anserine and sah | x-ray diffraction | A, B | 8V3, CA | — |
| Q8N4J0 | AlphaFold monomer V2.0 prediction for carnosine N-methyltransferase (Q8N4J0) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5YF0 chain A against the predicted model Q8N4J0: TM-score 1.00, RMSD 0.31 Å
- 5YF1 chain A against the predicted model Q8N4J0: TM-score 1.00, RMSD 0.36 Å
- 5YF0 chain A against the predicted model Q8N4J0: TM-score 0.99, RMSD 0.31 Å
- 5YF1 chain A against the predicted model Q8N4J0: TM-score 0.99, RMSD 0.36 Å
- 5YF2 chain A against the predicted model Q8N4J0: TM-score 0.99, RMSD 0.43 Å
- 5YF2 chain A against the predicted model Q8N4J0: TM-score 0.99, RMSD 0.43 Å
- 5YF1 chain B against the predicted model Q8N4J0: TM-score 0.99, RMSD 0.80 Å
- 5YF1 chain B against the predicted model Q8N4J0: TM-score 0.99, RMSD 0.80 Å
- 5YF0 chain B against the predicted model Q8N4J0: TM-score 0.99, RMSD 0.94 Å
- 5YF2 chain B against the predicted model Q8N4J0: TM-score 0.99, RMSD 0.82 Å
Elsewhere
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