UniProt Q8LFA9
Methyltransferase-like protein 2 (Q8LFA9)
Methyltransferase-like protein 2 (UniProt Q8LFA9), EC 2.1.1.-: 12 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 39 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q8LFA9
- Protein
- Methyltransferase-like protein 2
- EC
- 2.1.1.-
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 39 · 5 records with a druggable one
Structures
13 records of Q8LFA9 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7CV6 | RNA methyltransferase METTL4 | x-ray diffraction | B | SAH, A2M | 4 (best 0.76) |
| 7CV6 | RNA methyltransferase METTL4 | x-ray diffraction | B | A2M | — |
| 7CV7 | RNA methyltransferase METTL4 | x-ray diffraction | A, B | SAM | 11 (best 0.86) |
| 7CV7 | RNA methyltransferase METTL4 | x-ray diffraction | A, B | — | — |
| 7CV8 | RNA methyltransferase METTL4 | x-ray diffraction | A | — | — |
| 7CV8 | RNA methyltransferase METTL4 | x-ray diffraction | A | — | — |
| 7CV9 | RNA methyltransferase METTL4 | x-ray diffraction | C, A | SAH | 10 (best 0.88) |
| 7CV9 | RNA methyltransferase METTL4 | x-ray diffraction | C, A | — | — |
| 7CVA | RNA methyltransferase METTL4 | x-ray diffraction | A, B | — | 11 (best 0.74) |
| 7CVA | RNA methyltransferase METTL4 | x-ray diffraction | A, B | — | — |
| 7DPE | RNA methyltransferase METTL4 | x-ray diffraction | A | SAH | 3 (best 0.80) |
| 7DPE | RNA methyltransferase METTL4 | x-ray diffraction | A | — | — |
| Q8LFA9 | AlphaFold monomer V2.0 prediction for methyltransferase-like protein 2 (Q8LFA9) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7CV8 chain A against the predicted model Q8LFA9: TM-score 0.97, RMSD 1.29 Å
- 7CV8 chain A against the predicted model Q8LFA9: TM-score 0.97, RMSD 1.29 Å
- 7CV7 chain B against the predicted model Q8LFA9: TM-score 0.97, RMSD 1.53 Å
- 7CV6 chain B against the predicted model Q8LFA9: TM-score 0.97, RMSD 1.39 Å
- 7CV9 chain C against the predicted model Q8LFA9: TM-score 0.97, RMSD 1.50 Å
- 7DPE chain A against the predicted model Q8LFA9: TM-score 0.97, RMSD 1.55 Å
- 7CV7 chain B against the predicted model Q8LFA9: TM-score 0.96, RMSD 1.53 Å
- 7CV6 chain B against the predicted model Q8LFA9: TM-score 0.96, RMSD 1.39 Å
- 7CV9 chain C against the predicted model Q8LFA9: TM-score 0.96, RMSD 1.50 Å
- 7DPE chain A against the predicted model Q8LFA9: TM-score 0.96, RMSD 1.55 Å
Elsewhere
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