UniProt Q8GUI6
Probable lysine-specific demethylase JMJ14 (Q8GUI6)
Probable lysine-specific demethylase JMJ14 (UniProt Q8GUI6), EC 1.14.11.-: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8GUI6
- Protein
- Probable lysine-specific demethylase JMJ14
- EC
- 1.14.11.-
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 18 · 3 records with a druggable one
Structures
5 records of Q8GUI6 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5YKN | crystal structure of Arabidopsis thaliana JMJ14 catalytic domain | x-ray diffraction | A | NI, ZN | 4 (best 0.68) |
| 5YKN | Crystal structure of arabidopsis thaliana JMJ14 catalytic domain | x-ray diffraction | A | NI, ZN | — |
| 5YKO | Crystal structure of Arabidopsis thaliana JMJ14 catalytic domain in complex with NOG and H3K4me3… | x-ray diffraction | A | NI, ZN, OGA | 4 (best 0.69) |
| 5YKO | Crystal structure of arabidopsis thaliana JMJ14 catalytic domain in complex with nog and H3K4ME3… | x-ray diffraction | A | NI, ZN, OGA | — |
| Q8GUI6 | AlphaFold monomer V2.0 prediction for probable lysine-specific demethylase JMJ14 (Q8GUI6) | predicted | A | — | 10 (best 0.70) |
Ligands
Experiment against prediction
- 5YKO chain A against the predicted model Q8GUI6: TM-score 1.00, RMSD 0.34 Å
- 5YKO chain A against the predicted model Q8GUI6: TM-score 1.00, RMSD 0.34 Å
- 5YKN chain A against the predicted model Q8GUI6: TM-score 1.00, RMSD 0.43 Å
- 5YKN chain A against the predicted model Q8GUI6: TM-score 1.00, RMSD 0.43 Å
Elsewhere
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