UniProt Q8A6L0
alpha-galactosidase (Q8A6L0)
alpha-galactosidase (UniProt Q8A6L0), EC 3.2.1.22: 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8A6L0
- Protein
- alpha-galactosidase
- EC
- 3.2.1.22
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 27 · 3 records with a druggable one
Structures
5 records of Q8A6L0 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3A24 | Crystal structure of BT1871 retaining glycosidase | x-ray diffraction | A, B | CA | 9 (best 0.75) |
| 3A24 | Crystal structure of BT1871 retaining glycosidase | x-ray diffraction | A, B | CA | 9 (best 0.75) |
| 5E1Q | Mutant (D415G) GH97 alpha-galactosidase in complex with Gal-Lac | x-ray diffraction | A, B | BGC, GLA, GAL, CA | 9 (best 0.58) |
| 5E1Q | Mutant (D415G) GH97 alpha-galactosidase in complex with gal-lac | x-ray diffraction | A, B | — | — |
| Q8A6L0 | AlphaFold monomer V2.0 prediction for retaining alpha-galactosidase (Q8A6L0) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3A24 chain B against the predicted model Q8A6L0: TM-score 1.00, RMSD 0.18 Å
- 3A24 chain B against the predicted model Q8A6L0: TM-score 1.00, RMSD 0.18 Å
- 5E1Q chain A against the predicted model Q8A6L0: TM-score 1.00, RMSD 0.20 Å
- 5E1Q chain A against the predicted model Q8A6L0: TM-score 1.00, RMSD 0.20 Å
- 3A24 chain A against the predicted model Q8A6L0: TM-score 1.00, RMSD 0.24 Å
- 3A24 chain A against the predicted model Q8A6L0: TM-score 1.00, RMSD 0.24 Å
- 5E1Q chain B against the predicted model Q8A6L0: TM-score 1.00, RMSD 0.35 Å
- 5E1Q chain B against the predicted model Q8A6L0: TM-score 1.00, RMSD 0.35 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.