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UniProt Q86W50

U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase (Q86W50)

U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase (UniProt Q86W50), EC 2.1.1.-, 2.1.1.346: 16 experimental structures on GenesisL1, 3 ligands bound, 26 pockets. Binding sites, pockets, druggability and 3D structures in…

UniProt
Q86W50
Protein
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase
EC
2.1.1.-, 2.1.1.346, 2.1.1.62
Experimental structures
16
Predicted models
0
Ligands
3
Pockets
26 · 4 records with a druggable one

Structures

16 records of Q86W50 in the MolNFT archive: 16 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6B91Crystal structure of the N-terminal domain of human METTL16x-ray diffractionANA3 (best 0.62)
6B91Crystal structure of the N-terminal domain of human METTL16x-ray diffractionANA—
6B92Crystal structure of the N-terminal domain of human METTL16 in complex with sahx-ray diffractionA——
6DU4Crystal structure of hMettl16 catalytic domain in complex with MAT2A 3'UTR hairpin 1x-ray diffractionA—8 (best 0.44)
6DU4Crystal structure of HMETTL16 catalytic domain in complex with MAT2A 3'UTR hairpin 1x-ray diffractionA——
6DU5Crystal structure of hMettl16 catalytic domain in complex with MAT2A 3'UTR hairpin 6x-ray diffractionA—4 (best 0.60)
6DU5Crystal structure of HMETTL16 catalytic domain in complex with MAT2A 3'UTR hairpin 6x-ray diffractionA——
6GFKdelta-N METTL16 MTase domainx-ray diffractionA, B, CSAH, SO48 (best 0.74)
6GFKDelta-N METTL16 mtase domainx-ray diffractionA, B, CSO4—
6GFNMETTL16 MTase domainx-ray diffractionASAH3 (best 0.61)
6GFNMETTL16 mtase domainx-ray diffractionA——
6GT5METTL16 MTase domain (crystal form 2)x-ray diffractionA, B——
6GT5METTL16 mtase domain (crystal form 2)x-ray diffractionA, B——
6M1UCrystal structure of the vertebrate conserved region (VCR) of human METTL16x-ray diffractionA——
6M1UCrystal structure of the vertebrate conserved region (vcr) of human METTL16x-ray diffractionA——
Q86W50AlphaFold monomer V2.0 prediction for RNA N6-adenosine- methyltransferase METTL16 (Q86W50)———

Ligands

  • NA · Sodium ion · in 2 records
  • SAH · S-adenosyl-L-homocysteine · in 2 records
  • SO4 · Sulfate ion · in 2 records

Elsewhere

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