UniProt Q7LBC6
Lysine-specific demethylase 3B (Q7LBC6)
Lysine-specific demethylase 3B (UniProt Q7LBC6), EC 1.14.11.-: 60 experimental structures on GenesisL1, 36 ligands bound, 56 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q7LBC6
- Protein
- Lysine-specific demethylase 3B
- EC
- 1.14.11.-
- Experimental structures
- 60
- Predicted models
- 0
- Ligands
- 36
- Pockets
- 56 · 5 records with a druggable one
Structures
60 records of Q7LBC6 in the MolNFT archive: 60 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4C8D | Crystal structure of JmjC domain of human histone 3 Lysine-specific demethylase 3B (KDM3B) | x-ray diffraction | A | — | — |
| 4C8D | Crystal structure of jmjc domain of human histone 3 lysine-specific demethylase 3B (KDM3B) | x-ray diffraction | A | — | — |
| 5R7X | Pandda analysis group deposition of ground-state model of human JMJD1B | x-ray diffraction | A, B | CL, MN | — |
| 5RAA | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM009990a | x-ray diffraction | A, B | — | — |
| 5RAA | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM009990A | x-ray diffraction | A, B | S3Y, CL, MN | — |
| 5RAB | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001726a | x-ray diffraction | A, B | — | — |
| 5RAB | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM001726A | x-ray diffraction | A, B | S4Y, CL, MN | — |
| 5RAC | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001810a | x-ray diffraction | A, B | — | — |
| 5RAC | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM001810A | x-ray diffraction | A, B | O3M, CL, MN | — |
| 5RAD | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001568a | x-ray diffraction | A, B | — | — |
| 5RAD | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM001568A | x-ray diffraction | A, B | AYJ, CL, MN | — |
| 5RAE | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001558a | x-ray diffraction | A, B | — | — |
| 5RAE | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM001558A | x-ray diffraction | A, B | S5A, CL, MN | — |
| 5RAF | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001559a | x-ray diffraction | A, B | — | — |
| 5RAF | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM001559A | x-ray diffraction | A, B | S5G, CL, MN | — |
| 5RAG | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001767a | x-ray diffraction | A, B | — | — |
| 5RAG | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM001767A | x-ray diffraction | A, B | O3G, CL, MN | — |
| 5RAH | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM010032a | x-ray diffraction | A, B | — | — |
| 5RAH | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM010032A | x-ray diffraction | A, B | GX4, CL, MN | — |
| 5RAI | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with XS040404c | x-ray diffraction | A, B | — | — |
| 5RAI | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with XS040404C | x-ray diffraction | A, B | S3M, CL, MN | — |
| 5RAJ | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with BD009815A | x-ray diffraction | A, B | W77, CL, MN | — |
| 5RAK | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with XS040486B | x-ray diffraction | A, B | N6Y, CL, MN | — |
| 5RAL | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with XS039332c | x-ray diffraction | A, B | CL, MN, SNQ | 10 (best 0.69) |
| 5RAL | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with XS039332C | x-ray diffraction | A, B | CL, MN, SNQ | — |
| 5RAM | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with XS038544D | x-ray diffraction | A, B | S3V, CL, MN | — |
| 5RAN | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with XS039080d | x-ray diffraction | A, B | — | — |
| 5RAN | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with XS039080D | x-ray diffraction | A, B | RYP, CL, MN | — |
| 5RAO | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001084a | x-ray diffraction | A, B | — | — |
| 5RAO | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM001084A | x-ray diffraction | A, B | S3S, CL, MN | — |
| 5RAP | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM000707A | x-ray diffraction | A, B | S64, CL, MN | — |
| 5RAQ | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001577a | x-ray diffraction | A, B | — | — |
| 5RAQ | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM001577A | x-ray diffraction | A, B | S5J, CL, MN | — |
| 5RAR | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with TD000005c | x-ray diffraction | A, B | S9D, CL, MN | 14 (best 0.70) |
| 5RAR | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with TD000005C | x-ray diffraction | A, B | S9D, CL, MN | — |
| 5RAS | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with XS036302b | x-ray diffraction | A, B | — | — |
| 5RAS | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with XS036302B | x-ray diffraction | A, B | CL, MN, S3J | — |
| 5RAU | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with DA000165b | x-ray diffraction | A, B | — | — |
| 5RAU | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with DA000165B | x-ray diffraction | A, B | HGE, CL, MN | — |
| 5RAV | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001763a | x-ray diffraction | A, B | — | — |
| 5RAV | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM001763A | x-ray diffraction | A, B | S9G, CL, MN | — |
| 5RAW | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM009970a | x-ray diffraction | A, B | — | — |
| 5RAW | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM009970A | x-ray diffraction | A, B | JJ7, CL, MN | — |
| 5RAX | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM010054A | x-ray diffraction | A, B | CL, MN, S9J | — |
| 5RAY | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001469a | x-ray diffraction | A, B | S9M, CL, MN | 10 (best 0.70) |
| 5RAY | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM001469A | x-ray diffraction | A, B | S9M, CL, MN | — |
| 5RAZ | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM010013A | x-ray diffraction | A, B | K0G, CL, MN | — |
| 5RB0 | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM010020a | x-ray diffraction | A, B | CL, MN, GWA | 11 (best 0.69) |
| 5RB0 | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM010020A | x-ray diffraction | A, B | CL, MN, GWA | — |
| 5RB1 | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM001700A | x-ray diffraction | A, B | S4V, CL, MN | — |
| 5RB2 | PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001784a | x-ray diffraction | A, B | S9P, CL, MN | 11 (best 0.70) |
| 5RB2 | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM001784A | x-ray diffraction | A, B | S9P, CL, MN | — |
| 5RB3 | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with XS039249D | x-ray diffraction | A, B | MPV, CL, MN | — |
| 5RB4 | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM001677A | x-ray diffraction | A, B | A6Z, CL, MN | — |
| 5RB5 | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM010010A | x-ray diffraction | A, B | S9S, CL, MN | — |
| 5RB6 | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM001569A | x-ray diffraction | A, B | S9V, CL, MN | — |
| 5RB7 | Pandda analysis group deposition -- crystal structure of JMJD1B in complex with FM001648A | x-ray diffraction | A, B | S4D, CL, MN | — |
| 6RBJ | Crystal structure of KDM3B in complex with 5-(1H-tetrazol-5-yl)quinolin-8-ol | x-ray diffraction | A, B | JX8, MN, CL | — |
| 6RBJ | Crystal structure of KDM3B in complex with 5-(1H-tetrazol-5-yl) quinolin-8-ol | x-ray diffraction | A, B | JX8, MN, CL | — |
| Q7LBC6 | AlphaFold monomer V2.0 prediction for lysine-specific demethylase 3B (Q7LBC6) | — | — | — |
Ligands
- CL · Chloride ion · in 41 records
- MN · Manganese (II) ion · in 41 records
- GWA · ~{N}-(3-acetamidophenyl)-2-methoxy-ethanamide · in 2 records
- JX8 · 5-(1~{H}-1,2,3,4-tetrazol-5-yl)quinolin-8-ol · in 2 records
- S9D · 2-[4-[(3~{S})-pyrazolidin-3-yl]phenoxy]pyrimidine · in 2 records
- S9M · 2,4-difluoro-6-[(3S)-pyrazolidin-3-yl]phenol · in 2 records
- S9P · 2-methyl-1,3-benzoxazol-6-ol · in 2 records
- SNQ · 5-azanyl-2-pyrrol-1-yl-benzenecarbonitrile · in 2 records
- A6Z · 2-[4-(3-chlorophenyl)piperazin-1-ium-1-yl]ethanenitrile · in 1 record
- AYJ · 2-[cyclohexyl(methylsulfonyl)amino]ethanamide · in 1 record
- GX4 · cyclopropyl-[4-(4-fluorophenyl)piperazin-1-yl]methanone · in 1 record
- HGE · Ethyl 1-pyrazin-2-ylpiperidine-4-carboxylate · in 1 record
- JJ7 · 1-{4-[(2-methoxyethyl)amino]piperidin-1-yl}ethan-1-one · in 1 record
- K0G · N-phenyl-N'-pyridin-3-ylurea · in 1 record
- MPV · 1-methyl-3-(thiophen-2-yl)-1H-pyrazol-5-amine · in 1 record
- N6Y · 3-(pyridin-3-yl)aniline · in 1 record
- O3G · N-benzyl-1-(4-fluorophenyl)methanamine · in 1 record
- O3M · 4-[(3,4-dihydroisoquinolin-2(1H)-yl)methyl]phenol · in 1 record
- RYP · ~{N}-methyl-1-pyridin-4-yl-methanamine · in 1 record
- S3J · 2-(4-phenylpiperidin-1-yl)ethanoic acid · in 1 record
- S3M · (1-methyl-5-phenyl-pyrazol-3-yl)methanol · in 1 record
- S3S · Ethyl 2-pyridin-4-ylethanoate · in 1 record
- S3V · Pyridine-4-carboxylic acid · in 1 record
- S3Y · [(4S)-1-(4-chlorophenyl)-1,2,3-triazolidin-4-yl]methanol · in 1 record
- S4D · (1R,3S)-N-[(2H-1,3-benzodioxol-5-yl)methyl]-3-methylcyclopentan-1-amine · in 1 record
- S4V · ~{N}2-pyridin-2-ylbenzene-1,2-diamine · in 1 record
- S4Y · (2R,5S)-5-(4-chlorophenyl)oxolane-2-carbohydrazide · in 1 record
- S5A · 3-[4-(4-hydroxyphenyl)phenyl]propanoic acid · in 1 record
- S5G · (5~{R})-3,4,4-trimethyl-5-(oxidanylamino)-1,3-thiazolidine-2-thione · in 1 record
- S5J · 2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanenitrile · in 1 record
Elsewhere
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