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Ligand · JX8

JX8 · 5-(1~{H}-1,2,3,4-tetrazol-5-yl)quinolin-8-ol

JX8, 5-(1~{H}-1,2,3,4-tetrazol-5-yl)quinolin-8-ol (C10 H7 N5 O, 213.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
JX8
Formula
C10 H7 N5 O
Class
ligand
Structures
4
PDB entries
2

Binding sites

JX8 in 4 structures; the first of them:

  • 6RBI · Crystal structure of KDM5B in complex with 5-(1H-tetrazol-5-yl)quinolin-8-ol · JX8 A805 · binds TYR488, PHE496, HIS499, GLU501, ASN509, LYS517, TRP519, HIS587 and 1 more
  • 6RBJ · Crystal structure of KDM3B in complex with 5-(1H-tetrazol-5-yl)quinolin-8-ol · JX8 A1803 · binds TYR1541, THR1556, THR1557, HIS1560, ASP1562, ASN1568, TRP1614, HIS1689 and 2 more
  • 6RBI · Crystal structure of KDM5B in complex with 5-(1H-tetrazol-5-yl) quinolin-8-ol · JX8 A805 · binds TYR488, PHE496, HIS499, GLU501, ASN509, LYS517, TRP519, HIS587 and 1 more
  • 6RBJ · Crystal structure of KDM3B in complex with 5-(1H-tetrazol-5-yl) quinolin-8-ol · JX8 A1803 · binds TYR1541, THR1556, THR1557, HIS1560, ASP1562, ASN1568, TRP1614, HIS1689 and 2 more

Residues it binds most

HIS 6, ASN 6, LYS 6, THR 4, TRP 6, TYR 6, ASP 4, VAL 4, GLU 2, PHE 2 (residue and the binding sites it lines).

Found with

  • MN · Manganese (II) ion
  • EDO · 1,2-ethanediol
  • NA · Sodium ion
  • ZN · Zinc ion
  • CL · Chloride ion
  • PO4 · Phosphate ion

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