UniProt Q6Q760

Sodium leak channel non-selective protein (Q6Q760)

Sodium leak channel non-selective protein (UniProt Q6Q760): 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 54 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…

UniProt: Q6Q760
Protein: Sodium leak channel non-selective protein
Experimental structures: 4
Predicted models: 1
Ligands: 3
Pockets: 54 · 3 records with a druggable one

Structures

5 records of Q6Q760 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
7CU3	Structure of mammalian NALCN-FAM155A complex at 2.65 angstrom	electron microscopy	A	NAG, 6OU, CLR	20 (best 0.86)
7CU3	Structure of mammalian nalcn-FAM155A complex at 2.65 ångström	electron microscopy	A	NAG, 6OU, CLR	—
7W7G	Structure of Mammalian NALCN-FAM155A-UNC79-UNC80 quanternary complex	electron microscopy	C	NAG	14 (best 0.86)
7W7G	Structure of mammalian nalcn-FAM155A-UNC79-UNC80 quanternary complex	electron microscopy	C	NAG	—
Q6Q760	AlphaFold monomer V2.0 prediction for sodium leak channel non- selective protein (Q6Q760)	predicted	A	—	20 (best 0.87)

Ligands

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
6OU · [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate · in 2 records
CLR · Cholesterol · in 2 records

Experiment against prediction

7CU3 chain A against the predicted model Q6Q760: TM-score 1.00, RMSD 0.64 Å
7CU3 chain A against the predicted model Q6Q760: TM-score 1.00, RMSD 0.64 Å
7W7G chain C against the predicted model Q6Q760: TM-score 0.95, RMSD 1.59 Å
7W7G chain C against the predicted model Q6Q760: TM-score 0.95, RMSD 1.59 Å

Elsewhere

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