UniProt Q6PIF6
Unconventional myosin-VIIb (Q6PIF6)
Unconventional myosin-VIIb (UniProt Q6PIF6): 6 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 58 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6PIF6
- Protein
- Unconventional myosin-VIIb
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 58 · 7 records with a druggable one
Structures
7 records of Q6PIF6 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5MV7 | Structure of human Myosin 7b C-terminal MyTH4-FERM MF2 domain | x-ray diffraction | A | TAM, SO4 | 6 (best 0.62) |
| 5MV7 | Structure of human myosin 7B C-terminal MYTH4-ferm MF2 domain | x-ray diffraction | A | TAM, SO4 | 6 (best 0.62) |
| 5MV8 | Structure of human Myosin 7b C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain | x-ray diffraction | A | MG | 7 (best 0.60) |
| 5MV8 | Structure of human myosin 7B C-terminal MYTH4-ferm domain in complex with harmonin-a PDZ3 domain | x-ray diffraction | A | MG | 7 (best 0.60) |
| 5XBF | Crystal Structure of Myo7b C-terminal MyTH4-FERM in complex with USH1C PDZ3 | x-ray diffraction | A | MLT | 6 (best 0.56) |
| 5XBF | Crystal structure of MYO7B C-terminal MYTH4-ferm in complex with USH1C PDZ3 | x-ray diffraction | A | MLT | 6 (best 0.56) |
| Q6PIF6 | AlphaFold monomer V2.0 prediction for unconventional myosin-viib (Q6PIF6) | predicted | A | — | 20 (best 0.82) |
Ligands
Experiment against prediction
- 5XBF chain A against the predicted model Q6PIF6: TM-score 0.98, RMSD 1.03 Å
- 5XBF chain A against the predicted model Q6PIF6: TM-score 0.98, RMSD 1.03 Å
- 5MV8 chain A against the predicted model Q6PIF6: TM-score 0.96, RMSD 1.18 Å
- 5MV8 chain A against the predicted model Q6PIF6: TM-score 0.96, RMSD 1.18 Å
- 5MV7 chain A against the predicted model Q6PIF6: TM-score 0.96, RMSD 1.58 Å
- 5MV7 chain A against the predicted model Q6PIF6: TM-score 0.96, RMSD 1.58 Å
Elsewhere
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