UniProt Q68CP4
Heparan-alpha-glucosaminide N-acetyltransferase (Q68CP4)
Heparan-alpha-glucosaminide N-acetyltransferase (UniProt Q68CP4), EC 2.3.1.78: 8 experimental structures on GenesisL1, 10 ligands bound, 114 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q68CP4
- Protein
- Heparan-alpha-glucosaminide N-acetyltransferase
- EC
- 2.3.1.78
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 10
- Pockets
- 114 · 7 records with a druggable one
Structures
8 records of Q68CP4 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8JL1 | membrane proteins | electron microscopy | A, B | NAG, ACO, D12, C14, CLR, D10 | 16 (best 0.83) |
| 8JL3 | membrane proteins | electron microscopy | A, B | NAG, ACO, D12, C14, CLR, D10 | 17 (best 0.83) |
| 8JL4 | membrane proteins | electron microscopy | A, B | NAG, UV6, COA, C14, CLR, D10 | 19 (best 0.83) |
| 8TU9 | Cryo-EM structure of HGSNAT-acetyl-CoA complex at pH 7.5 | electron microscopy | A, B | ACO, NAG | 20 (best 0.84) |
| 8VLV | Cryo-EM structure of human HGSNAT in inactive state | electron microscopy | A, B | NAG | 15 (best 0.78) |
| 8VLY | Cryo-EM structure of human HGSNAT in transition state | electron microscopy | A, B | NAG | 12 (best 0.77) |
| 8W4A | membrane proteins | electron microscopy | B, A | NAG, UV6, ACO, C14, CLR, D10 | 15 (best 0.83) |
| Q68CP4 | AlphaFold monomer V2.0 prediction for heparan-alpha-glucosaminide N-acetyltransferase (Q68CP4) | — | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 7 records
- ACO · Acetyl coenzyme *A · in 4 records
- C14 · Tetradecane · in 4 records
- CLR · Cholesterol · in 4 records
- D10 · Decane · in 4 records
- D12 · Dodecane · in 4 records
- R16 · Hexadecane · in 4 records
- HP6 · Heptane · in 2 records
- UV6 · ~{N}-[(2~{S},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-2-[[(2~{R},4~{R})-4-methyl-2-oxidanyl-3,4-dihydro-2~{H}-chromen-7-yl]oxy]-4,5-bis(oxidanyl)oxan-3-yl]ethanamide · in 2 records
- COA · Coenzyme A · in 1 record
Elsewhere
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