UniProt Q61193
Ral guanine nucleotide dissociation stimulator-like 2 (Q61193)
Ral guanine nucleotide dissociation stimulator-like 2 (UniProt Q61193): 7 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q61193
- Protein
- Ral guanine nucleotide dissociation stimulator-like 2
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 13 · 2 records with a druggable one
Structures
8 records of Q61193 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1RLF | Structure determination of the RAS-binding domain of the ral-specific guanine nucleotide exchange… | solution nmr | A | — | — |
| 1RLF | Structure determination of the RAS-binding domain of the ral-specific guanine nucleotide exchange… | solution nmr | A | — | — |
| 4JGW | The conformation of a docking site for SH3 domains is pre-selected in the Guanine Nucleotide… | x-ray diffraction | A, B | — | — |
| 4JGW | The conformation of a docking site for SH3 domains is pre-selected in the guanine nucleotide… | x-ray diffraction | A, B | — | — |
| 5CM8 | Structural Basis for the Selectivity of Guanine Nucleotide Exchange Factors for the small G-protein… | x-ray diffraction | A | — | 5 (best 0.67) |
| 5CM8 | Structural basis for the selectivity of guanine nucleotide exchange factors for the small G-protein… | x-ray diffraction | A | — | — |
| 5CM9 | Structural basis for the selectivity of guanine nucleotide exchange factors for the small G-protein… | x-ray diffraction | A, B | — | — |
| Q61193 | AlphaFold monomer V2.0 prediction for ral guanine nucleotide dissociation stimulator-like 2 (Q61193) | predicted | A | — | 8 (best 0.69) |
Experiment against prediction
- 4JGW chain B against the predicted model Q61193: TM-score 0.99, RMSD 0.78 Å
- 4JGW chain B against the predicted model Q61193: TM-score 0.99, RMSD 0.78 Å
- 5CM8 chain A against the predicted model Q61193: TM-score 0.98, RMSD 0.94 Å
- 5CM8 chain A against the predicted model Q61193: TM-score 0.98, RMSD 0.94 Å
- 5CM9 chain B against the predicted model Q61193: TM-score 0.98, RMSD 1.08 Å
- 5CM9 chain A against the predicted model Q61193: TM-score 0.98, RMSD 1.16 Å
- 4JGW chain A against the predicted model Q61193: TM-score 0.98, RMSD 1.16 Å
- 4JGW chain A against the predicted model Q61193: TM-score 0.98, RMSD 1.16 Å
- 1RLF chain A against the predicted model Q61193: TM-score 0.56, RMSD 3.47 Å
- 1RLF chain A against the predicted model Q61193: TM-score 0.56, RMSD 3.47 Å
Elsewhere
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