UniProt Q57834
Tyrosine--tRNA ligase (Q57834)
Tyrosine--tRNA ligase (UniProt Q57834), EC 6.1.1.1: 70 experimental structures on GenesisL1, 8 ligands bound, 28 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q57834
- Protein
- Tyrosine--tRNA ligase
- EC
- 6.1.1.1
- Experimental structures
- 70
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 28 · 7 records with a druggable one
Structures
70 records of Q57834 in the MolNFT archive: 70 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1J1U | Crystal structure of archaeal tyrosyl-tRNA synthetase complexed with tRNA(Tyr) and L-tyrosine | x-ray diffraction | A | — | — |
| 1J1U | Crystal structure of archaeal tyrosyl-tRNA synthetase complexed with TRNA(TYR) and L-tyrosine | x-ray diffraction | A | — | — |
| 1U7D | crystal structure of apo M. jannashii tyrosyl-tRNA synthetase | x-ray diffraction | A, B | — | — |
| 1U7D | Crystal structure of apo M. jannashii tyrosyl-tRNA synthetase | x-ray diffraction | A, B | — | — |
| 1U7X | crystal structure of a mutant M. jannashii tyrosyl-tRNA synthetase specific for O-methyl-tyrosine | x-ray diffraction | A, B | — | — |
| 1U7X | Crystal structure of a mutant M. jannashii tyrosyl-tRNA synthetase specific for O-methyl-tyrosine | x-ray diffraction | A, B | — | — |
| 1ZH0 | Crystal Structure of L-3-(2-napthyl)alanine-tRNA synthetase in complex with L-3-(2-napthyl)alanine | x-ray diffraction | A | — | — |
| 1ZH0 | Crystal structure of L-3-(2-NAPTHYL)ALANINE-tRNA synthetase in complex with L-3-(2-NAPTHYL)ALANINE | x-ray diffraction | A | — | — |
| 1ZH6 | Crystal Structure of p-acetylphenylalanine-tRNA synthetase in complex with p-acetylphenylalanine | x-ray diffraction | A | — | — |
| 1ZH6 | Crystal structure of P-acetylphenylalanine-tRNA synthetase in complex with P-acetylphenylalanine | x-ray diffraction | A | — | — |
| 2AG6 | Crystal structure of p-bromo-l-phenylalanine-tRNA sythetase in complex with p-bromo-l-phenylalanine | x-ray diffraction | A | — | — |
| 2AG6 | Crystal structure of P-bromo-L-phenylalanine-tRNA sythetase in complex with P-bromo-L-phenylalanine | x-ray diffraction | A | — | — |
| 2HGZ | Crystal structure of a p-benzoyl-L-phenylalanyl-tRNA synthetase | x-ray diffraction | A | — | — |
| 2HGZ | Crystal structure of a P-benzoyl-L-phenylalanyl-tRNA synthetase | x-ray diffraction | A | — | — |
| 2PXH | Crystal structure of a bipyridylalanyl-tRNA synthetase | x-ray diffraction | A | — | — |
| 2PXH | Crystal structure of a bipyridylalanyl-tRNA synthetase | x-ray diffraction | A | — | — |
| 2ZP1 | Structual basis of iodo-tyrosine recognition by engineered archeal tyrosyl-tRNA synthetase | x-ray diffraction | A | — | — |
| 2ZP1 | Structual basis of iodo-tyrosine recognition by engineered archeal tyrosyl-tRNA synthetase | x-ray diffraction | A | — | — |
| 3D6U | Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase | x-ray diffraction | A | — | — |
| 3D6U | Crystal structure of 4-(TRIFLUOROMETHYLDIAZIRINYL)PHENYLALANYL-tRNA synthetase | x-ray diffraction | A | — | — |
| 3D6V | Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase | x-ray diffraction | A | — | — |
| 3D6V | Crystal structure of 4-(TRIFLUOROMETHYLDIAZIRINYL)PHENYLALANYL-tRNA synthetase | x-ray diffraction | A | — | — |
| 3N2Y | Crystal structure of tyrosyl-tRNA synthetase complexed with p-(2-tetrazolyl)-phenylalanine | x-ray diffraction | A, B | — | — |
| 3N2Y | Crystal structure of tyrosyl-tRNA synthetase complexed with P-(2- tetrazolyl)-phenylalanine | x-ray diffraction | A, B | — | — |
| 3QE4 | An evolved aminoacyl-tRNA Synthetase with atypical polysubstrate specificity | x-ray diffraction | A, B | — | — |
| 3QE4 | An evolved aminoacyl-tRNA synthetase with atypical polysubstrate specificity | x-ray diffraction | A, B | — | — |
| 4HJR | Crystal structure of F2YRS | x-ray diffraction | A, B | — | — |
| 4HJR | Crystal structure of F2YRS | x-ray diffraction | A, B | — | — |
| 4HJX | Crystal structure of F2YRS complexed with F2Y | x-ray diffraction | A, B | — | — |
| 4HJX | Crystal structure of F2YRS complexed with F2Y | x-ray diffraction | A, B | — | — |
| 4HK4 | Crystal structure of apo Tyrosine-tRNA ligase mutant protein | x-ray diffraction | A | — | — |
| 4HK4 | Crystal structure of apo tyrosine-tRNA ligase mutant protein | x-ray diffraction | A | — | — |
| 4HPW | Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid… | x-ray diffraction | A | — | — |
| 4HPW | Crystal structure of tyrosine-tRNA ligase mutant complexed with unnatural amino acid… | x-ray diffraction | A | — | — |
| 4ND6 | Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the open form | x-ray diffraction | A | — | — |
| 4ND6 | Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the open form | x-ray diffraction | A | — | — |
| 4ND7 | Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the closed form | x-ray diffraction | A | — | — |
| 4ND7 | Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the closed form | x-ray diffraction | A | — | — |
| 4NDA | Crystal structure of 3-nitro-tyrosine tRNA synthetase (5B) bound to 3-nitro-tyrosine | x-ray diffraction | A | — | — |
| 4NDA | Crystal structure of 3-nitro-tyrosine tRNA synthetase (5B) bound to 3- nitro-tyrosine | x-ray diffraction | A | — | — |
| 4NX2 | Crystal structure of DCYRS complexed with DCY | x-ray diffraction | A | — | — |
| 4NX2 | Crystal structure of dcyrs complexed with dcy | x-ray diffraction | A | — | — |
| 4PBR | Crystal structure of the M. jannaschii G2 tRNA synthetase variant bound to… | x-ray diffraction | A | — | — |
| 4PBR | Crystal structure of the M. jannaschii G2 tRNA synthetase variant bound to… | x-ray diffraction | A | — | — |
| 4PBS | Crystal structure of the M. jannaschii F9 tRNA synthetase variant bound to… | x-ray diffraction | A | — | — |
| 4PBS | Crystal structure of the M. jannaschii F9 tRNA synthetase variant bound to… | x-ray diffraction | A | — | — |
| 4PBT | Crystal structure of the M. jannaschii G2 tRNA synthetase variant bound to… | x-ray diffraction | A | — | — |
| 4PBT | Crystal structure of the M. jannaschii G2 tRNA synthetase variant bound to… | x-ray diffraction | A | — | — |
| 5L7P | In silico-powered specific incorporation of photocaged Dopa at multiple protein sites | x-ray diffraction | A, B | CA, CL, BUU | — |
| 5L7P | In silico-powered specific incorporation of photocaged dopa at multiple protein sites | x-ray diffraction | A, B | CA, CL, BUU | — |
| 5N5U | Structure of p-boronophenylalanyl tRNA synthetase in complex with p-boronophenylalanine and… | x-ray diffraction | A | AMP, 7N8, CL | 2 (best 0.75) |
| 5N5U | Structure of P-boronophenylalanyl tRNA synthetase in complex with P- boronophenylalanine and… | x-ray diffraction | A | AMP, CL | — |
| 5N5V | Structure of p-boronophenylalanyl tRNA synthetase - apo form | x-ray diffraction | A, B, C, D, E, F, G, H | CL | 19 (best 0.78) |
| 5N5V | Structure of P-boronophenylalanyl tRNA synthetase - apo form | x-ray diffraction | A, B, C, D, E, F, G, H | CL | — |
| 5NSF | Structure of azuala | x-ray diffraction | B, A, C, D | 96Z, CA | — |
| 5U36 | Crystal Structure Of A Mutant M. Jannashii Tyrosyl-tRNA Synthetase | x-ray diffraction | A, B | — | — |
| 5U36 | Crystal structure of a mutant M. jannashii tyrosyl-tRNA synthetase | x-ray diffraction | A, B | — | — |
| 6WRK | Crystal structure of 3rd-generation Mj 3-nitro-tyrosine tRNA synthetase (A7") bound to… | x-ray diffraction | A | NA, NIY | 1 (best 0.79) |
| 6WRK | Crystal structure of 3RD-generation mj 3-nitro-tyrosine tRNA synthetase ("A7") bound to… | x-ray diffraction | A | NA | — |
| 6WRN | Crystal structure of Mj 3-nitro-tyrosine tRNA synthetase (5B) C70A variant bound to 3-nitro-tyrosine | x-ray diffraction | A | NA, NIY | 1 (best 0.78) |
10 records more on the page itself.
Ligands
- NA · Sodium ion · in 8 records
- CL · Chloride ion · in 6 records
- NIY · Meta-nitro-tyrosine · in 4 records
- CA · Calcium ion · in 3 records
- AMP · Adenosine monophosphate · in 2 records
- BUU · (2~{S})-2-azanyl-3-[3-[(2-nitrophenyl)methoxy]-4-oxidanyl-phenyl]propanoic acid · in 2 records
- 7N8 · 4-Borono-L-phenylalanine · in 1 record
- 96Z · (2~{S})-2-azanyl-3-(2,6-dihydroazulen-1-yl)propanoic acid · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.