UniProt Q56220
NADH-quinone oxidoreductase subunit 4 (Q56220)
NADH-quinone oxidoreductase subunit 4 (UniProt Q56220): 26 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q56220
- Protein
- NADH-quinone oxidoreductase subunit 4
- Experimental structures
- 26
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 2 · 0 records with a druggable one
Structures
27 records of Q56220 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2FUG | Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus | x-ray diffraction | 4, D, M, V | — | — |
| 2FUG | Crystal structure of the hydrophilic domain of respiratory complex I from thermus thermophilus | x-ray diffraction | 4, D, M, V | — | — |
| 2YBB | Fitted model for bovine mitochondrial supercomplex I1III2IV1 by single particle cryo-EM (EMD-1876) | electron microscopy | 4 | — | — |
| 2YBB | Fitted model for bovine mitochondrial supercomplex I1III2IV1 by single particle cryo-EM (emd-1876) | electron microscopy | 4 | — | — |
| 3I9V | Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus… | x-ray diffraction | 4, D | — | — |
| 3I9V | Crystal structure of the hydrophilic domain of respiratory complex I from thermus thermophilus… | x-ray diffraction | 4, D | — | — |
| 3IAM | Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus… | x-ray diffraction | 4, D | — | — |
| 3IAM | Crystal structure of the hydrophilic domain of respiratory complex I from thermus thermophilus… | x-ray diffraction | 4, D | — | — |
| 3IAS | Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus… | x-ray diffraction | 4, D, M, V | — | — |
| 3IAS | Crystal structure of the hydrophilic domain of respiratory complex I from thermus thermophilus… | x-ray diffraction | 4, D, M, V | — | — |
| 3M9S | Crystal structure of respiratory complex I from Thermus thermophilus | x-ray diffraction | 4, D | — | — |
| 3M9S | Crystal structure of respiratory complex I from thermus thermophilus | x-ray diffraction | 4, D | — | — |
| 4HEA | Crystal structure of the entire respiratory complex I from Thermus thermophilus | x-ray diffraction | 4, E | — | — |
| 4HEA | Crystal structure of the entire respiratory complex I from thermus thermophilus | x-ray diffraction | 4, E | — | — |
| 6I0D | Respiratory complex I from Thermus thermophilus with bound Decyl-Ubiqui | x-ray diffraction | 4, E | SF4, DCQ | — |
| 6I0D | Respiratory complex I from thermus thermophilus with bound decyl- ubiquinone | x-ray diffraction | 4, E | SF4, DCQ | — |
| 6I1P | Respiratory complex I from Thermus thermophilus with bound NADH | x-ray diffraction | 4, E | SF4 | — |
| 6I1P | Respiratory complex I from thermus thermophilus with bound NADH | x-ray diffraction | 4, E | SF4 | — |
| 6Q8O | Respiratory complex I from thermus thermophilus with bound piericidin a | x-ray diffraction | 4, E | HQH, SF4 | — |
| 6Q8W | Respiratory complex I from thermus thermophilus with bound aureothin. | x-ray diffraction | 4, E | HQW, SF4 | — |
| 6Q8X | Respiratory complex I from thermus thermophilus with bound pyridaben. | x-ray diffraction | 4, E | HQK, SF4 | — |
| 6Y11 | Respiratory complex I from thermus thermophilus | x-ray diffraction | 4, E | SF4 | — |
| 6ZIY | Respiratory complex I from thermus thermophilus, NADH dataset, major state | electron microscopy | 4 | SF4 | — |
| 6ZJL | Respiratory complex I from thermus thermophilus, NAD+ dataset, major state | electron microscopy | 4 | SF4 | — |
| 6ZJN | Respiratory complex I from thermus thermophilus, NADH dataset, minor state | electron microscopy | 4 | — | — |
| 6ZJY | Respiratory complex I from thermus thermophilus, NAD+ dataset, minor state | electron microscopy | 4 | — | — |
| Q56220 | AlphaFold monomer V2.0 prediction for NADH-quinone oxidoreductase subunit 4 (Q56220) | predicted | A | — | 2 (best 0.46) |
Ligands
Experiment against prediction
- 6Q8W chain 4 against the predicted model Q56220: TM-score 0.98, RMSD 0.94 Å
- 4HEA chain 4 against the predicted model Q56220: TM-score 0.98, RMSD 0.97 Å
- 4HEA chain 4 against the predicted model Q56220: TM-score 0.98, RMSD 0.97 Å
- 6I1P chain 4 against the predicted model Q56220: TM-score 0.98, RMSD 1.00 Å
- 6I1P chain 4 against the predicted model Q56220: TM-score 0.98, RMSD 1.00 Å
- 6Q8X chain 4 against the predicted model Q56220: TM-score 0.98, RMSD 1.00 Å
- 6Y11 chain 4 against the predicted model Q56220: TM-score 0.98, RMSD 1.00 Å
- 6ZIY chain 4 against the predicted model Q56220: TM-score 0.98, RMSD 1.02 Å
- 6I0D chain 4 against the predicted model Q56220: TM-score 0.98, RMSD 1.04 Å
- 6I0D chain 4 against the predicted model Q56220: TM-score 0.98, RMSD 1.04 Å
Elsewhere
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