UniProt Q51487
Outer membrane protein OprM (Q51487)
Outer membrane protein OprM (UniProt Q51487): 18 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q51487
- Protein
- Outer membrane protein OprM
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 7 · 1 record with a druggable one
Structures
19 records of Q51487 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1WP1 | Crystal structure of the drug-discharge outer membrane protein, OprM | x-ray diffraction | A, B | — | — |
| 1WP1 | Crystal structure of the drug-discharge outer membrane protein, oprm | x-ray diffraction | A, B | — | — |
| 3D5K | Crystal structure of the OprM channel in a non-symmetrical space group | x-ray diffraction | A, B, C | — | — |
| 3D5K | Crystal structure of the oprm channel in a non-symmetrical space group | x-ray diffraction | A, B, C | — | — |
| 4Y1K | Palmitoylated oprm outer membrane factor | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4Y1K | Palmitoylated oprm outer membrane factor | x-ray diffraction | A, B, C, D, E, F | — | — |
| 6IOK | Cryo-EM structure of multidrug efflux pump MexAB-OprM (0 degree state) | electron microscopy | A, B, C | — | — |
| 6IOK | Cryo-EM structure of multidrug efflux pump mexab-oprm (0 degree state) | electron microscopy | A, B, C | — | — |
| 6IOL | Cryo-EM structure of multidrug efflux pump MexAB-OprM (60 degree state) | electron microscopy | A, B, C | — | — |
| 6IOL | Cryo-EM structure of multidrug efflux pump mexab-oprm (60 degree state) | electron microscopy | A, B, C | — | — |
| 6TA5 | OprM-MexA complex from the MexAB-OprM Pseudomonas aeruginosa whole assembly reconstituted in… | electron microscopy | A, B, C | — | — |
| 6TA5 | Oprm-mexa complex from the mexab-oprm pseudomonas aeruginosa whole assembly reconstituted in… | electron microscopy | A, B, C | — | — |
| 6TA6 | MexAB assembly of the Pseudomonas MexAB-OprM efflux pump reconstituted in nanodiscs | electron microscopy | A, B, C | — | — |
| 6TA6 | Mexab assembly of the pseudomonas mexab-oprm efflux pump reconstituted in nanodiscs | electron microscopy | A, B, C | — | — |
| 6ZRE | Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux… | x-ray diffraction | A, B | PLM, SO4 | — |
| 6ZRE | Deciphering the role of the channel constrictions in the opening mechanism of mexab-oprm efflux… | x-ray diffraction | A, B | PLM, SO4 | — |
| 7AKZ | Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux… | x-ray diffraction | A, B | PLM | 5 (best 0.72) |
| 7AKZ | Deciphering the role of the channel constrictions in the opening mechanism of mexab-oprm efflux… | x-ray diffraction | A, B | PLM | — |
| Q51487 | AlphaFold monomer V2.0 prediction for outer membrane protein oprm (Q51487) | predicted | A | — | 2 (best 0.39) |
Ligands
Experiment against prediction
- 1WP1 chain A against the predicted model Q51487: TM-score 0.95, RMSD 1.80 Å
- 1WP1 chain A against the predicted model Q51487: TM-score 0.95, RMSD 1.80 Å
- 3D5K chain A against the predicted model Q51487: TM-score 0.95, RMSD 1.80 Å
- 3D5K chain A against the predicted model Q51487: TM-score 0.95, RMSD 1.80 Å
- 4Y1K chain A against the predicted model Q51487: TM-score 0.95, RMSD 1.80 Å
- 4Y1K chain A against the predicted model Q51487: TM-score 0.95, RMSD 1.80 Å
- 6ZRE chain A against the predicted model Q51487: TM-score 0.95, RMSD 1.80 Å
- 6ZRE chain A against the predicted model Q51487: TM-score 0.95, RMSD 1.80 Å
- 6ZRE chain B against the predicted model Q51487: TM-score 0.95, RMSD 1.81 Å
- 6ZRE chain B against the predicted model Q51487: TM-score 0.95, RMSD 1.81 Å
Elsewhere
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