MolNFT v1 · #26440 · protein

Crystal structure of the drug-discharge outer membrane protein, oprm

1WP1 · Outer membrane protein oprm: “Crystal structure of the drug-discharge outer membrane protein, oprm”. X-ray diffraction, 6 pockets (best druggability 0.39). MolNFT v1 #26440 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 1WP1
Type: protein
Length: 861 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Outer membrane protein oprm
UniProt: Q51487
Pockets: 6 · best druggability 0.39

Structure

x-ray diffraction · 2 distinct chains · 63% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Outer membrane protein oprm	protein	456	61% helix, 6% strand	Q51487
B	Outer membrane protein oprm	protein	405	66% helix, 0% strand	Q51487

Pockets

6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	101	0.39	0.76	22	empty
2	78	0.35	0.76	16	empty
3	90	0.33	0.73	14	empty
4	51	0.32	0.78	11	empty
5	75	0.30	0.73	15	empty

Compared structures

1WP1 · Crystal structure of the drug-discharge outer membrane protein, OprM · the same entry in another collection · chain A against A, TM-score 1.00
Q51487 · AlphaFold monomer V2.0 prediction for outer membrane protein oprm (Q51487) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q51487
Elsewhere: RCSB PDB 1WP1 · PDBe 1WP1 · UniProt Q51487

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