UniProt Q4D3W2
Dihydroorotate dehydrogenase (fumarate) (Q4D3W2)
Dihydroorotate dehydrogenase (fumarate) (UniProt Q4D3W2): 112 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q4D3W2
- Protein
- Dihydroorotate dehydrogenase (fumarate)
- Experimental structures
- 112
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 2 · 1 record with a druggable one
Structures
113 records of Q4D3W2 in the MolNFT archive: 112 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2E68 | Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with dihydroorotate | x-ray diffraction | A, B | — | — |
| 2E68 | Crystal structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with dihydroorotate | x-ray diffraction | A, B | — | — |
| 2E6A | Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with orotate | x-ray diffraction | A, B | — | — |
| 2E6A | Crystal structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with orotate | x-ray diffraction | A, B | — | — |
| 2E6D | Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with fumarate | x-ray diffraction | A, B | — | — |
| 2E6D | Crystal structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with fumarate | x-ray diffraction | A, B | — | — |
| 2E6F | Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with oxonate | x-ray diffraction | A, B | — | — |
| 2E6F | Crystal structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with oxonate | x-ray diffraction | A, B | — | — |
| 3C3N | Crystal structure of dihydroorotate dehydrogenase from Trypanosoma cruzi strain Y | x-ray diffraction | A, B, C, D | — | — |
| 3C3N | Crystal structure of dihydroorotate dehydrogenase from trypanosoma cruzi strain Y | x-ray diffraction | A, B, C, D | — | — |
| 3W1A | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-halogenated orotate… | x-ray diffraction | A, B | — | — |
| 3W1A | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-halogenated orotate… | x-ray diffraction | A, B | — | — |
| 3W1L | Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-chloroorotate | x-ray diffraction | A, B | — | — |
| 3W1L | Crystal structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-chloroorotate | x-ray diffraction | A, B | — | — |
| 3W1M | Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-bromoorotate | x-ray diffraction | A, B | — | — |
| 3W1M | Crystal structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-bromoorotate | x-ray diffraction | A, B | — | — |
| 3W1N | Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-iodoorotate | x-ray diffraction | A, B | — | — |
| 3W1N | Crystal structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-iodoorotate | x-ray diffraction | A, B | — | — |
| 3W1P | Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with… | x-ray diffraction | A, B | — | — |
| 3W1P | Crystal structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with… | x-ray diffraction | A, B | — | — |
| 3W1Q | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with NL-2 | x-ray diffraction | A, B | — | — |
| 3W1Q | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with nl-2 | x-ray diffraction | A, B | — | — |
| 3W1R | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-045a | x-ray diffraction | A, B | — | — |
| 3W1R | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-3-045A | x-ray diffraction | A, B | — | — |
| 3W1T | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-095 | x-ray diffraction | A, B | — | — |
| 3W1T | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-3-095 | x-ray diffraction | A, B | — | — |
| 3W1U | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-111 | x-ray diffraction | A, B | — | — |
| 3W1U | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-3-111 | x-ray diffraction | A, B | — | — |
| 3W1X | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-121 | x-ray diffraction | A, B | — | — |
| 3W1X | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-3-121 | x-ray diffraction | A, B | — | — |
| 3W22 | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-125 | x-ray diffraction | A, B | — | — |
| 3W22 | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-3-125 | x-ray diffraction | A, B | — | — |
| 3W23 | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-131 | x-ray diffraction | A, B | — | — |
| 3W23 | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-3-131 | x-ray diffraction | A, B | — | — |
| 3W2J | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-135 | x-ray diffraction | A, B | — | — |
| 3W2J | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-3-135 | x-ray diffraction | A, B | — | — |
| 3W2K | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-165 | x-ray diffraction | A, B | — | — |
| 3W2K | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-3-165 | x-ray diffraction | A, B | — | — |
| 3W2L | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-169 | x-ray diffraction | A, B | — | — |
| 3W2L | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-3-169 | x-ray diffraction | A, B | — | — |
| 3W2M | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-183 | x-ray diffraction | A, B | — | — |
| 3W2M | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-3-183 | x-ray diffraction | A, B | — | — |
| 3W2N | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-185 | x-ray diffraction | A, B | — | — |
| 3W2N | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-3-185 | x-ray diffraction | A, B | — | — |
| 3W2U | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-193 | x-ray diffraction | A, B | — | — |
| 3W2U | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-3-193 | x-ray diffraction | A, B | — | — |
| 3W3O | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-053 | x-ray diffraction | A, B | — | — |
| 3W3O | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-4-053 | x-ray diffraction | A, B | — | — |
| 3W6Y | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with TT2-2-199 | x-ray diffraction | A, B | — | — |
| 3W6Y | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with TT2-2-199 | x-ray diffraction | A, B | — | — |
| 3W70 | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-095 | x-ray diffraction | A, B | — | — |
| 3W70 | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-4-095 | x-ray diffraction | A, B | — | — |
| 3W71 | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-097 | x-ray diffraction | A, B | — | — |
| 3W71 | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-4-097 | x-ray diffraction | A, B | — | — |
| 3W72 | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-107 | x-ray diffraction | A, B | — | — |
| 3W72 | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-4-107 | x-ray diffraction | A, B | — | — |
| 3W73 | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-129 | x-ray diffraction | A, B | — | — |
| 3W73 | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-4-129 | x-ray diffraction | A, B | — | — |
| 3W74 | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-139 | x-ray diffraction | A, B | — | — |
| 3W74 | Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with mii-4-139 | x-ray diffraction | A, B | — | — |
53 records more on the page itself.
Ligands
Experiment against prediction
- 2E68 chain B against the predicted model Q4D3W2: TM-score 1.00, RMSD 0.31 Å
- 2E68 chain B against the predicted model Q4D3W2: TM-score 1.00, RMSD 0.31 Å
- 3W1L chain A against the predicted model Q4D3W2: TM-score 1.00, RMSD 0.37 Å
- 3W1L chain A against the predicted model Q4D3W2: TM-score 1.00, RMSD 0.37 Å
- 3W1M chain A against the predicted model Q4D3W2: TM-score 1.00, RMSD 0.37 Å
- 3W1M chain A against the predicted model Q4D3W2: TM-score 1.00, RMSD 0.37 Å
- 5EA9 chain A against the predicted model Q4D3W2: TM-score 1.00, RMSD 0.37 Å
- 2E6A chain A against the predicted model Q4D3W2: TM-score 1.00, RMSD 0.37 Å
- 2E6A chain A against the predicted model Q4D3W2: TM-score 1.00, RMSD 0.37 Å
- 2E6D chain A against the predicted model Q4D3W2: TM-score 1.00, RMSD 0.37 Å
Elsewhere
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