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UniProt Q47396

Macrolide 2'-phosphotransferase (Q47396)

Macrolide 2'-phosphotransferase (UniProt Q47396): 14 experimental structures on GenesisL1, 8 ligands bound, 5 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q47396
Protein
Macrolide 2'-phosphotransferase
Experimental structures
14
Predicted models
0
Ligands
8
Pockets
5 · 5 records with a druggable one

Structures

14 records of Q47396 in the MolNFT archive: 14 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5IGHMacrolide 2'-phosphotransferase type Ix-ray diffractionASO41 (best 0.76)
5IGHMacrolide 2'-phosphotransferase type Ix-ray diffractionA——
5IGIMacrolide 2'-phosphotransferase type I - complex with guanosine and azithromycinx-ray diffractionAGMP, ZIT1 (best 0.73)
5IGIMacrolide 2'-phosphotransferase type I - complex with guanosine and azithromycinx-ray diffractionA——
5IGJMacrolide 2'-phosphotransferase type I - complex with guanosine and clarithromycinx-ray diffractionAGMP, CTY1 (best 0.73)
5IGJMacrolide 2'-phosphotransferase type I - complex with guanosine and clarithromycinx-ray diffractionA——
5IGPMacrolide 2'-phosphotransferase type I - complex with GDP and erythromycinx-ray diffractionAGDP, ERY—
5IGPMacrolide 2'-phosphotransferase type I - complex with GDP and erythromycinx-ray diffractionA——
5IGRMacrolide 2'-phosphotransferase type I - complex with GDP and oleandomycinx-ray diffractionAGDP, ZIO, NH41 (best 0.75)
5IGRMacrolide 2'-phosphotransferase type I - complex with GDP and oleandomycinx-ray diffractionA——
5IGSMacrolide 2'-phosphotransferase type I - complex with guanosine and oleandomycinx-ray diffractionAZIO, GMP—
5IGSMacrolide 2'-phosphotransferase type I - complex with guanosine and oleandomycinx-ray diffractionA——
5IGTMacrolide 2'-phosphotransferase type I - complex with guanosine and erythromycinx-ray diffractionAGMP, ERY1 (best 0.73)
5IGTMacrolide 2'-phosphotransferase type I - complex with guanosine and erythromycinx-ray diffractionA——

Ligands

  • GMP · Guanosine · in 4 records
  • ERY · Erythromycin A · in 2 records
  • GDP · Guanosine-5'-diphosphate · in 2 records
  • ZIO · (3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-hydroxy-5,7,8,11,13,15-hexamethyl-4,10-dioxo-14-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1,9-dioxaspiro[2.13]hexadec-12-yl 2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranoside · in 2 records
  • CTY · Clarithromycin · in 1 record
  • NH4 · Ammonium ion · in 1 record
  • SO4 · Sulfate ion · in 1 record
  • ZIT · Azithromycin · in 1 record

Elsewhere

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