UniProt Q47155
DNA polymerase IV (Q47155)
DNA polymerase IV (UniProt Q47155), EC 2.7.7.7: 56 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 89 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q47155
- Protein
- DNA polymerase IV
- EC
- 2.7.7.7
- Experimental structures
- 56
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 89 · 14 records with a druggable one
Structures
57 records of Q47155 in the MolNFT archive: 56 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1OK7 | A Conserved protein binding-site on Bacterial Sliding Clamps | x-ray diffraction | C | — | — |
| 1OK7 | A conserved protein binding-site on bacterial sliding clamps | x-ray diffraction | C | — | — |
| 1UNN | Complex of beta-clamp processivity factor and little finger domain of PolIV | x-ray diffraction | C, D | SO4 | 2 (best 0.51) |
| 1UNN | Complex of beta-clamp processivity factor and little finger domain of poliv | x-ray diffraction | C, D | — | — |
| 4IR1 | Polymerase-DNA Complex | x-ray diffraction | F, A | — | — |
| 4IR1 | Polymerase-DNA complex | x-ray diffraction | F, A | — | — |
| 4IR9 | Polymerase-DNA complex | x-ray diffraction | F, A | — | — |
| 4IR9 | Polymerase-DNA complex | x-ray diffraction | F, A | — | — |
| 4IRC | Polymerase-DNA complex | x-ray diffraction | F, A | — | — |
| 4IRC | Polymerase-DNA complex | x-ray diffraction | F, A | — | — |
| 4IRD | Structure of Polymerase-DNA complex | x-ray diffraction | F, A | — | — |
| 4IRD | Structure of polymerase-DNA complex | x-ray diffraction | F, A | — | — |
| 4IRK | structure of Polymerase-DNA complex, dna | x-ray diffraction | B, A | — | — |
| 4IRK | Structure of polymerase-DNA complex, DNA | x-ray diffraction | B, A | — | — |
| 4Q43 | Polymerase-damaged DNA complex | x-ray diffraction | A, F | — | — |
| 4Q43 | Polymerase-damaged DNA complex | x-ray diffraction | A, F | — | — |
| 4Q44 | Polymerase-Damaged DNA Complex | x-ray diffraction | A, F | — | — |
| 4Q44 | Polymerase-damaged DNA complex | x-ray diffraction | A, F | — | — |
| 4Q45 | DNA Polymerase- damaged DNA complex | x-ray diffraction | F, A | — | — |
| 4Q45 | DNA polymerase- damaged DNA complex | x-ray diffraction | F, A | — | — |
| 4R8U | S-SAD structure of DINB-DNA Complex | x-ray diffraction | A, B | — | — |
| 4R8U | S-sad structure of dinb-DNA complex | x-ray diffraction | A, B | — | — |
| 5YUR | DNA polymerase IV - DNA ternary complex 1 | x-ray diffraction | F, A | TTP, NA | 8 (best 0.80) |
| 5YUR | DNA polymerase IV - DNA ternary complex 1 | x-ray diffraction | F, A | TTP, NA | — |
| 5YUS | DNA polymerase IV - DNA ternary complex 2 | x-ray diffraction | F, A | TTP, MG | — |
| 5YUS | DNA polymerase IV - DNA ternary complex 2 | x-ray diffraction | F, A | TTP, MG | — |
| 5YUT | DNA polymerase IV - DNA ternary complex 3 | x-ray diffraction | F, A | TTP, MG | 6 (best 0.81) |
| 5YUT | DNA polymerase IV - DNA ternary complex 3 | x-ray diffraction | F, A | TTP, MG | — |
| 5YUU | DNA polymerase IV - DNA ternary complex 4 | x-ray diffraction | F, A | TTP, MG | 6 (best 0.81) |
| 5YUU | DNA polymerase IV - DNA ternary complex 4 | x-ray diffraction | F, A | TTP, MG | — |
| 5YUV | DNA polymerase IV - DNA ternary complex 5 | x-ray diffraction | F, A | MG, TTP | 6 (best 0.81) |
| 5YUV | DNA polymerase IV - DNA ternary complex 5 | x-ray diffraction | F, A | MG | — |
| 5YUW | DNA polymerase IV - DNA ternary complex 6 | x-ray diffraction | A, F | TTP, MG | 6 (best 0.81) |
| 5YUW | DNA polymerase IV - DNA ternary complex 6 | x-ray diffraction | A, F | TTP, MG | — |
| 5YUX | DNA polymerase IV - DNA ternary complex 8 | x-ray diffraction | F, A | TTP, MG, DPO | 7 (best 0.81) |
| 5YUX | DNA polymerase IV - DNA ternary complex 8 | x-ray diffraction | F, A | TTP, MG, DPO | — |
| 5YUY | DNA polymerase IV - DNA ternary complex 9 | x-ray diffraction | F, A | MG, DPO, TTP | 9 (best 0.80) |
| 5YUY | DNA polymerase IV - DNA ternary complex 9 | x-ray diffraction | F, A | MG, DPO | — |
| 5YUZ | DNA polymerase IV - DNA ternary complex 11 | x-ray diffraction | F, A | MG, DPO, TTP | 7 (best 0.80) |
| 5YUZ | DNA polymerase IV - DNA ternary complex 11 | x-ray diffraction | F, A | MG, DPO | — |
| 5YV0 | DNA polymerase IV - DNA ternary complex 12 | x-ray diffraction | F, A | MG, PO4, DPO, TTP | 6 (best 0.81) |
| 5YV0 | DNA polymerase IV - DNA ternary complex 12 | x-ray diffraction | F, A | MG, PO4, DPO | — |
| 5YV1 | DNA polymerase IV - DNA ternary complex 13 | x-ray diffraction | F, A | MG, PO4, DPO | 6 (best 0.80) |
| 5YV1 | DNA polymerase IV - DNA ternary complex 13 | x-ray diffraction | F, A | MG, PO4, DPO | — |
| 5YV2 | DNA polymerase IV - DNA ternary complex 14 | x-ray diffraction | F, A | MG, PO4 | — |
| 5YV2 | DNA polymerase IV - DNA ternary complex 14 | x-ray diffraction | F, A | MG, PO4 | — |
| 5YV3 | DNA polymerase IV - DNA ternary complex 7 | x-ray diffraction | F, A | MG, DPO, TTP | 7 (best 0.80) |
| 5YV3 | DNA polymerase IV - DNA ternary complex 7 | x-ray diffraction | F, A | MG, DPO | — |
| 5YYD | DNA polymerase IV - ternary complex 15 | x-ray diffraction | F, A | TTW, NA | 6 (best 0.80) |
| 5YYD | DNA polymerase IV - ternary complex 15 | x-ray diffraction | F, A | TTW, NA | — |
| 5YYE | DNA polymerase IV - ternary complex 16 | x-ray diffraction | F, A | TTW, MG | 7 (best 0.80) |
| 5YYE | DNA polymerase IV - ternary complex 16 | x-ray diffraction | F, A | TTW, MG | — |
| 5ZLV | DNA polymerase IV - DNA ternary complex with 50mM MgCl2 | x-ray diffraction | F, A | MG, PO4, DPO | — |
| 5ZLV | DNA polymerase IV - DNA ternary complex with 50MM MGCL2 | x-ray diffraction | F, A | MG, PO4, DPO | — |
| 6IG1 | DNA polymerase IV - DNA ternary complex 10 | x-ray diffraction | F, A | MG, DPO | — |
| 6IG1 | DNA polymerase IV - DNA ternary complex 10 | x-ray diffraction | F, A | MG, DPO | — |
| Q47155 | AlphaFold monomer V2.0 prediction for DNA polymerase IV (Q47155) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 30 records
- TTP · Thymidine-5'-triphosphate · in 17 records
- DPO · Diphosphate · in 16 records
- PO4 · Phosphate ion · in 8 records
- NA · Sodium ion · in 4 records
- TTW · 5'-O-[hydroxy{[hydroxy(phosphonoamino) phosphoryl]oxy}phosphoryl]thymidine · in 4 records
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 4R8U chain A against the predicted model Q47155: TM-score 1.00, RMSD 0.38 Å
- 4R8U chain A against the predicted model Q47155: TM-score 1.00, RMSD 0.38 Å
- 4R8U chain B against the predicted model Q47155: TM-score 1.00, RMSD 0.47 Å
- 4R8U chain B against the predicted model Q47155: TM-score 1.00, RMSD 0.47 Å
- 5YUX chain A against the predicted model Q47155: TM-score 0.99, RMSD 0.36 Å
- 5YUX chain A against the predicted model Q47155: TM-score 0.99, RMSD 0.36 Å
- 5YYE chain F against the predicted model Q47155: TM-score 0.99, RMSD 0.36 Å
- 5YYE chain F against the predicted model Q47155: TM-score 0.99, RMSD 0.36 Å
- 5YUV chain A against the predicted model Q47155: TM-score 0.99, RMSD 0.37 Å
- 5YUV chain A against the predicted model Q47155: TM-score 0.99, RMSD 0.37 Å
Elsewhere
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