UniProt Q46389
5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase (Q46389)
5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase (UniProt Q46389): 12 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 6 pockets. Binding sites, druggability and experiment…
- UniProt
- Q46389
- Protein
- 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 6 · 2 records with a druggable one
Structures
13 records of Q46389 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1F6Y | Mad crystal structure analysis of methyltetrahydrofolate: CORRINOID/IRON-sulfur protein… | x-ray diffraction | A, B | — | 3 (best 0.51) |
| 1F6Y | Mad crystal structure analysis of methyltetrahydrofolate: CORRINOID/IRON-sulfur protein… | x-ray diffraction | A, B | — | — |
| 2E7F | 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase complexed with… | x-ray diffraction | A, B | CA, C2F | 3 (best 0.55) |
| 2E7F | 5-methyltetrahydrofolate CORRINOID/IRON sulfur protein methyltransferase complexed with… | x-ray diffraction | A, B | — | — |
| 2OGY | Asn199Ala Mutant of the 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase… | x-ray diffraction | A, B | — | — |
| 2OGY | ASN199ALA mutant of the 5-methyltetrahydrofolate CORRINOID/IRON sulfur protein methyltransferase… | x-ray diffraction | A, B | — | — |
| 4DJD | Crystal structure of folate-free corrinoid iron-sulfur protein (CFeSP) in complex with its… | x-ray diffraction | A, B | — | — |
| 4DJD | Crystal structure of folate-free corrinoid iron-sulfur protein (cfesp) in complex with its… | x-ray diffraction | A, B | — | — |
| 4DJE | Crystal structure of folate-bound corrinoid iron-sulfur protein (CFeSP) in complex with its… | x-ray diffraction | A, B | — | — |
| 4DJE | Crystal structure of folate-bound corrinoid iron-sulfur protein (cfesp) in complex with its… | x-ray diffraction | A, B | — | — |
| 4DJF | Crystal structure of folate-bound corrinoid iron-sulfur protein (CFeSP) in complex with its… | x-ray diffraction | A, B | — | — |
| 4DJF | Crystal structure of folate-bound corrinoid iron-sulfur protein (cfesp) in complex with its… | x-ray diffraction | A, B | — | — |
| Q46389 | AlphaFold monomer V2.0 prediction for 5-METHYLTETRAHYDROFOLATE:CORRINOID/IRON-sulfur protein co… | predicted | A | — | — |
Ligands
Experiment against prediction
- 2E7F chain B against the predicted model Q46389: TM-score 0.99, RMSD 0.53 Å
- 2E7F chain B against the predicted model Q46389: TM-score 0.99, RMSD 0.53 Å
- 4DJD chain B against the predicted model Q46389: TM-score 0.99, RMSD 0.53 Å
- 4DJD chain B against the predicted model Q46389: TM-score 0.99, RMSD 0.53 Å
- 4DJD chain A against the predicted model Q46389: TM-score 0.99, RMSD 0.54 Å
- 4DJD chain A against the predicted model Q46389: TM-score 0.99, RMSD 0.54 Å
- 1F6Y chain B against the predicted model Q46389: TM-score 0.99, RMSD 0.54 Å
- 1F6Y chain B against the predicted model Q46389: TM-score 0.99, RMSD 0.54 Å
- 2OGY chain B against the predicted model Q46389: TM-score 0.99, RMSD 0.54 Å
- 2OGY chain B against the predicted model Q46389: TM-score 0.99, RMSD 0.54 Å
Elsewhere
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