Ligand · COB

COB · Co-methylcobalamin

COB, Co-methylcobalamin (C63 H91 Co N13 O14 P +1, 1344.4 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (5 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…

Component: COB
Formula: C63 H91 Co N13 O14 P +1
Class: ligand
Structures: 6
PDB entries: 5

Binding sites

COB in 6 structures; the first of them:

7QBV · B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and… · COB A504 · binds TYR23, PHE24, VAL27, TYR47, ARG210, ALA212, ASN217, GLY218 and 36 more
5UJC · Crystal structure of a C.ELEGANS B12-trafficking protein cblc, a human mmachc homologue · COB A300 · binds ALA38, VAL39, SER43, PHE45, ASP121, PRO130, ILE132, LEU133 and 19 more
7QBS · B12-dependent radical SAM methyltransferase, MMP10 with [4FE-4S] cluster, cobalamin… · COB A504 · binds TYR23, PHE24, TYR47, VAL52, GLU54, ARG210, ALA212, ASN217 and 37 more
7QBT · B12-dependent radical SAM methyltransferase, MMP10 with [4FE-4S] cluster, cobalamin, and… · COB A504 · binds TYR23, PHE24, TYR47, ARG210, ALA212, ASN217, GLY218, LEU219 and 31 more
7QBU · B12-dependent radical SAM methyltransferase, MMP10 with [4FE-4S] cluster, cobalamin, and… · COB A504 · binds TYR23, PHE24, VAL27, TYR47, ARG210, ALA212, ASN217, GLY218 and 31 more
7QBV · B12-dependent radical SAM methyltransferase, MMP10 with [4FE-4S] cluster, cobalamin, and… · COB A504 · binds TYR23, PHE24, TYR47, ARG210, ALA212, ASN217, GLY218, LEU219 and 33 more

Residues it binds most

LEU 16, ILE 16, PHE 16, PRO 16, GLY 15, ARG 15, ASN 16, ASP 16, GLU 15, THR 16 (residue and the binding sites it lines).

Found with

SF4 · Iron/sulfur cluster
FE · Fe (III) ion
NA · Sodium ion
MTA · 5'-deoxy-5'-methylthioadenosine
SAH · S-adenosyl-L-homocysteine
GOL · Glycerol
PEG · Di(hydroxyethyl)ether
TAR · D(-)-tartaric acid
TLA · L(+)-tartaric acid

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.