UniProt Q15562
Transcriptional enhancer factor TEF-4 (Q15562)
Transcriptional enhancer factor TEF-4 (UniProt Q15562): 25 experimental structures on GenesisL1, 16 ligands bound, 14 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q15562
- Protein
- Transcriptional enhancer factor TEF-4
- Experimental structures
- 25
- Predicted models
- 0
- Ligands
- 16
- Pockets
- 14 · 3 records with a druggable one
Structures
25 records of Q15562 in the MolNFT archive: 25 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3L15 | Human Tead2 transcriptional factor | x-ray diffraction | A, B | — | — |
| 3L15 | Human TEAD2 transcriptional factor | x-ray diffraction | A, B | — | — |
| 5DQ8 | Crystal structure of human transcription factor TEAD2 in complex with flufenamic acid | x-ray diffraction | A, B | — | — |
| 5DQE | Crystal structure of human transcription factor TEAD2 in complex with bromo-fenamic acid | x-ray diffraction | A, B | 5E4 | — |
| 5DQE | Crystal structure of human transcription factor TEAD2 in complex with bromo-fenamic acid | x-ray diffraction | A, B | — | — |
| 5EMV | Crystal structure of the palmitoylated human TEAD2 transcription factor | x-ray diffraction | A, B | — | — |
| 5EMV | Crystal structure of the palmitoylated human TEAD2 transcription factor | x-ray diffraction | A, B | — | — |
| 5HGU | Crystal structure of human transcription factor TEAD2 in complex with palmitate | x-ray diffraction | A, B | — | — |
| 6CDY | Crystal structure of tead complexed with its inhibitor | x-ray diffraction | A, B | EY1 | — |
| 6E5G | Crystal structure of human TEAD2-Yap binding domain covalently bound to an allosteric regulator | x-ray diffraction | B, A | HUY | 6 (best 0.83) |
| 6E5G | Crystal structure of human TEAD2-yap binding domain covalently bound to an allosteric regulator | x-ray diffraction | B, A | HUY | — |
| 6S60 | Crystal structure of hTEAD2 in complex with a trisubstituted pyrazole inhibitor | x-ray diffraction | A, B | MYR, KX8 | — |
| 6S60 | Crystal structure of HTEAD2 in complex with a trisubstituted pyrazole inhibitor | x-ray diffraction | A, B | MYR, KX8 | — |
| 6S64 | Crystal structure of hTEAD2 in complex with a trisubstituted pyrazole inhibitor | x-ray diffraction | A, B | MYR, PLM, KXE | 5 (best 0.84) |
| 6S64 | Crystal structure of HTEAD2 in complex with a trisubstituted pyrazole inhibitor | x-ray diffraction | A, B | MYR, PLM, KXE | — |
| 6S66 | Crystal structure of HTEAD2 in complex with a trisubstituted pyrazole inhibitor | x-ray diffraction | A, B | MYR, KWW | — |
| 6S69 | Crystal structure of HTEAD2 in complex with a trisubstituted pyrazole inhibitor | x-ray diffraction | A, B | MYR, KX5 | — |
| 6S6J | Crystal structure of HTEAD2 in complex with a trisubstituted pyrazole inhibitor | x-ray diffraction | A, B | MYR, KXH | — |
| 6UYB | Crystal structure of TEAD2 bound to compound 1 | x-ray diffraction | A, B | QSJ | — |
| 6UYC | Crystal structure of TEAD2 bound to compound 2 | x-ray diffraction | A, B | QLV | — |
| 6VAH | Crystal structure of human TEAD2 transcription factor in complex with Flufenamic acid derivative | x-ray diffraction | A, B | QZ1, UNX | — |
| 6VAH | Crystal structure of human TEAD2 transcription factor in complex with flufenamic acid derivative | x-ray diffraction | A, B | QZ1, UNX | — |
| 7OYJ | Crystal structure of HTEAD2 in complex with fragment at the interface 2 | x-ray diffraction | A, B | PLM, 3DI | — |
| 8CUH | Crystal structure of human TEAD2 complexed with its inhibitor TM2. | x-ray diffraction | A, B | P0I | 3 (best 0.82) |
| Q15562 | AlphaFold monomer V2.0 prediction for transcriptional enhancer factor tef-4 (Q15562) | — | — | — |
Ligands
- MYR · Myristic acid · in 7 records
- PLM · Palmitic acid · in 3 records
- HUY · 1-(2-{[3-(trifluoromethyl)phenyl]amino}phenyl)ethan-1-one · in 2 records
- KX8 · 4-[3-(3,4-dichlorophenyl)-4-[(phenylmethyl) carbamoyl]pyrazol-1-yl]butanoic acid · in 2 records
- KXE · 3-[3-(3,4-dichlorophenyl)-4-[(phenylmethyl) carbamoyl]pyrazol-1-yl]propanoic acid · in 2 records
- QZ1 · 2-fluoro-6-[(3-hexylphenyl)amino]benzoic acid · in 2 records
- UNX · Unknown atom or ion · in 2 records
- 3DI · 3-(1~{H}-pyrazol-5-yl)aniline · in 1 record
- 5E4 · 2-[(3-bromophenyl)amino]benzoic acid · in 1 record
- EY1 · 2-[(4H-1,2,4-triazol-3-yl)sulfanyl]-N-{4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-yl]phenyl}acetamide · in 1 record
- KWW · 1-(2-azanylethyl)-3-(3,4-dichlorophenyl)-~{N}-(phenylmethyl)pyrazole-4-carboxamide · in 1 record
- KX5 · 3-[3-(3,4-dichlorophenyl)-4-(2-phenylethylcarbamoyl) pyrazol-1-yl]propanoic acid · in 1 record
- KXH · Ethyl 1-(4-azanylbutyl)-3-(3,4-dichlorophenyl)pyrazole-4-carboxylate · in 1 record
- P0I · 4-[3-(2-cyclohexylethoxy)benzoyl]-N-phenylpiperazine-1-carboxamide · in 1 record
- QLV · N-{5-[(E)-2-(4,4-difluorocyclohexyl)ethenyl]-6-methoxypyridin-3-yl}methanesulfonamide · in 1 record
- QSJ · (3R,4R)-1-{3-[(E)-2-(4-chlorophenyl)ethenyl]-4-methoxy-5-methylphenyl}-3,4-dihydroxypyrrolidin-2-one · in 1 record
Elsewhere
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