MolNFT v2 · #164770 · protein
Crystal structure of hTEAD2 in complex with a trisubstituted pyrazole inhibitor
6S60: “Crystal structure of hTEAD2 in complex with a trisubstituted pyrazole inhibitor”. X-ray diffraction at 2, 2 ligands (MYR, KX8). MolNFT v2 #164770 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6S60
- Type
- protein
- Length
- 418 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2
- Source
- Homo sapiens
- UniProt
- Q15562
- Ligands
- MYR, KX8
Structure
x-ray diffraction · resolution 2 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 204 | — | Q15562 |
| B | — | protein | 214 | — | Q15562 |
Ligands and binding sites
- MYR · Myristic acid · ligand · 2 copies · chains A, B
- KX8 · 4-[3-(3,4-dichlorophenyl)-4-[(phenylmethyl) carbamoyl]pyrazol-1-yl]butanoic acid · ligand · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6S60 · Crystal structure of HTEAD2 in complex with a trisubstituted pyrazole inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15562
- Elsewhere: RCSB PDB 6S60 · PDBe 6S60 · UniProt Q15562
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