UniProt Q14149
MORC family CW-type zinc finger protein 3 (Q14149)
MORC family CW-type zinc finger protein 3 (UniProt Q14149): 12 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q14149
- Protein
- MORC family CW-type zinc finger protein 3
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 11 · 2 records with a druggable one
Structures
13 records of Q14149 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4QQ4 | CW-type zinc finger of MORC3 in complex with the amino terminus of histone H3 | x-ray diffraction | A, B | — | — |
| 4QQ4 | Cw-type zinc finger of MORC3 in complex with the amino terminus of histone H3 | x-ray diffraction | A, B | — | — |
| 5SVI | MORC3 CW domain in complex with unmodified histone H3 | x-ray diffraction | A, B | ZN | 1 (best 0.42) |
| 5SVI | MORC3 cw domain in complex with unmodified histone H3 | x-ray diffraction | A, B | ZN | — |
| 5SVX | MORC3 CW in complex with histone H3K4me3 | x-ray diffraction | A | ZN | — |
| 5SVX | MORC3 cw in complex with histone H3K4ME3 | x-ray diffraction | A | ZN | — |
| 5SVY | MORC3 CW in complex with histone H3K4me1 | x-ray diffraction | A | ZN | — |
| 5SVY | MORC3 cw in complex with histone H3K4ME1 | x-ray diffraction | A | ZN | — |
| 6O1E | The crystal structure of human MORC3 ATPase-CW in complex with AMPPNP | x-ray diffraction | A | ZN, MG, ANP | 4 (best 0.75) |
| 6O1E | The crystal structure of human MORC3 ATPase-cw in complex with amppnp | x-ray diffraction | A | ZN, MG, ANP | — |
| 6O5W | Crystal structure of MORC3 CW domain fused with viral influenza A NS1 peptide | x-ray diffraction | A | ZN | — |
| 6O5W | Crystal structure of MORC3 cw domain fused with viral influenza a NS1 peptide | x-ray diffraction | A | ZN | — |
| Q14149 | AlphaFold monomer V2.0 prediction for morc family cw-type zinc finger protein 3 (Q14149) | predicted | A | — | 6 (best 0.76) |
Ligands
Experiment against prediction
- 6O1E chain A against the predicted model Q14149: TM-score 0.99, RMSD 0.82 Å
- 6O1E chain A against the predicted model Q14149: TM-score 0.99, RMSD 0.82 Å
- 5SVI chain A against the predicted model Q14149: TM-score 0.93, RMSD 0.83 Å
- 5SVI chain A against the predicted model Q14149: TM-score 0.93, RMSD 0.83 Å
- 5SVX chain A against the predicted model Q14149: TM-score 0.93, RMSD 0.90 Å
- 5SVX chain A against the predicted model Q14149: TM-score 0.93, RMSD 0.90 Å
- 5SVY chain A against the predicted model Q14149: TM-score 0.92, RMSD 0.97 Å
- 5SVY chain A against the predicted model Q14149: TM-score 0.92, RMSD 0.97 Å
- 4QQ4 chain A against the predicted model Q14149: TM-score 0.92, RMSD 1.09 Å
- 4QQ4 chain A against the predicted model Q14149: TM-score 0.92, RMSD 1.09 Å
Elsewhere
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