UniProt Q13838
Spliceosome RNA helicase DDX39B (Q13838)
Spliceosome RNA helicase DDX39B (UniProt Q13838), EC 3.6.4.13: 12 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q13838
- Protein
- Spliceosome RNA helicase DDX39B
- EC
- 3.6.4.13
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 10 · 1 record with a druggable one
Structures
13 records of Q13838 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1T5I | Crystal structure of the C-terminal domain of UAP56 | x-ray diffraction | A | — | — |
| 1T5I | Crystal structure of the C-terminal domain of UAP56 | x-ray diffraction | A | — | — |
| 1T6N | Crystal structure of the N-terminal domain of human UAP56 | x-ray diffraction | A, B | — | — |
| 1T6N | Crystal structure of the N-terminal domain of human UAP56 | x-ray diffraction | A, B | — | — |
| 1XTI | Structure of Wildtype human UAP56 | x-ray diffraction | A | — | — |
| 1XTI | Structure of wildtype human UAP56 | x-ray diffraction | A | — | — |
| 1XTJ | structure of human UAP56 in complex with ADP | x-ray diffraction | A | — | — |
| 1XTJ | Structure of human UAP56 in complex with ADP | x-ray diffraction | A | — | — |
| 1XTK | structure of DECD to DEAD mutation of human UAP56 | x-ray diffraction | A | — | — |
| 1XTK | Structure of decd to dead mutation of human UAP56 | x-ray diffraction | A | — | — |
| 7APK | Structure of the human tho - UAP56 complex | electron microscopy | H, P, h, p | — | — |
| 8ENK | Crystal structure of UAP56 in complex with Tho1, the yeast homolog of human SARNP | x-ray diffraction | A, B | ADP, BEF, MG | 10 (best 0.66) |
| Q13838 | AlphaFold monomer V2.0 prediction for spliceosome RNA helicase DDX39B (Q13838) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8ENK chain A against the predicted model Q13838: TM-score 0.98, RMSD 0.97 Å
- 1T6N chain B against the predicted model Q13838: TM-score 0.98, RMSD 0.77 Å
- 1T6N chain B against the predicted model Q13838: TM-score 0.98, RMSD 0.77 Å
- 1T6N chain A against the predicted model Q13838: TM-score 0.98, RMSD 0.78 Å
- 1T6N chain A against the predicted model Q13838: TM-score 0.98, RMSD 0.78 Å
- 8ENK chain B against the predicted model Q13838: TM-score 0.98, RMSD 1.12 Å
- 7APK chain p against the predicted model Q13838: TM-score 0.93, RMSD 1.51 Å
- 7APK chain P against the predicted model Q13838: TM-score 0.93, RMSD 1.51 Å
- 7APK chain H against the predicted model Q13838: TM-score 0.93, RMSD 1.51 Å
- 7APK chain h against the predicted model Q13838: TM-score 0.93, RMSD 1.51 Å
Elsewhere
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