MolNFT v1 · #27767 · protein
Structure of human UAP56 in complex with ADP
1XTJ · Probable ATP-dependent RNA helicase P47: “Structure of human UAP56 in complex with ADP”. X-ray diffraction, 2 ligands (ADP, MG), 2 pockets (best druggability 0.67). MolNFT v1 #27767 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1XTJ
- Type
- protein
- Length
- 374 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable ATP-dependent RNA helicase P47
- UniProt
- Q13838
- Ligands
- ADP, MG
- Pockets
- 2 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable ATP-dependent RNA helicase P47 | protein | 374 | 40% helix, 17% strand | Q13838 |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · chains A
- MG · Magnesium ion · metal · chains A
- ACY · Acetic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 701 | 0.67 | 0.75 | 65 | MG, ADP |
| 2 | 72 | 0.40 | 0.79 | 17 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13838
- Elsewhere: RCSB PDB 1XTJ · PDBe 1XTJ · UniProt Q13838
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