UniProt Q09161
Nuclear cap-binding protein subunit 1 (Q09161)
Nuclear cap-binding protein subunit 1 (UniProt Q09161): 23 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 34 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q09161
- Protein
- Nuclear cap-binding protein subunit 1
- Experimental structures
- 23
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 34 · 3 records with a druggable one
Structures
24 records of Q09161 in the MolNFT archive: 23 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1H2T | Structure of the human nuclear cap-binding-complex (CBC) in complex with a cap analogue m7GpppG | x-ray diffraction | C | — | — |
| 1H2T | Structure of the human nuclear cap-binding-complex (cbc) in complex with a cap analogue M7GPPPG | x-ray diffraction | C | — | — |
| 1H2U | Structure of the human nuclear cap-binding-complex (CBC) in complex with a cap analogue m7GpppG | x-ray diffraction | A, B | — | — |
| 1H2U | Structure of the human nuclear cap-binding-complex (cbc) in complex with a cap analogue M7GPPPG | x-ray diffraction | A, B | — | — |
| 1H2V | Structure of the human nuclear cap-binding-complex (CBC) | x-ray diffraction | C | — | — |
| 1H2V | Structure of the human nuclear cap-binding-complex (cbc) | x-ray diffraction | C | — | — |
| 1H6K | nuclear Cap Binding Complex | x-ray diffraction | A, B, C | — | — |
| 1H6K | Nuclear cap binding complex | x-ray diffraction | A, B, C | — | — |
| 1N52 | Cap Binding Complex | x-ray diffraction | A | — | — |
| 1N52 | Cap binding complex | x-ray diffraction | A | — | — |
| 1N54 | Cap Binding Complex m7GpppG free | x-ray diffraction | A | — | — |
| 1N54 | Cap binding complex M7GPPPG free | x-ray diffraction | A | — | — |
| 3FEX | Crystal structure of the CBC-importin alpha complex. | x-ray diffraction | A | — | — |
| 3FEX | Crystal structure of the cbc-importin alpha complex. | x-ray diffraction | A | — | — |
| 3FEY | Crystal structure of the CBC-importin alpha complex. | x-ray diffraction | A | — | — |
| 3FEY | Crystal structure of the cbc-importin alpha complex. | x-ray diffraction | A | — | — |
| 5OO6 | Complex of human nuclear cap-binding complex with ARS2 C-terminal peptide | x-ray diffraction | A, D, G, J, M, P, S, V | — | — |
| 5OO6 | Complex of human nuclear cap-binding complex with ARS2 C-terminal peptide | x-ray diffraction | A, D, G, J, M, P, S, V | — | — |
| 5OOB | Complex of human nuclear cap-binding complex with M7GTP and nelf-E C-terminal peptide | x-ray diffraction | A, C, F, I | — | — |
| 5OOB | Complex of human nuclear cap-binding complex with M7GTP and nelf-E C- terminal peptide | x-ray diffraction | A, C, F, I | — | — |
| 6D0Y | X-ray Crystal Structure of PGC-1beta C-terminus bound to the CBP80-CBP20 Cap Binding Complex | x-ray diffraction | C | MG | 11 (best 0.78) |
| 6D0Y | X-ray crystal structure of pgc-1BETA C-terminus bound to the CBP80- CBP20 cap binding complex | x-ray diffraction | C | MG | — |
| 8SUY | Cryo-EM structure of the human cap binding complex (CBC) | electron microscopy | A | — | 12 (best 0.77) |
| Q09161 | AlphaFold monomer V2.0 prediction for nuclear cap-binding protein subunit 1 (Q09161) | predicted | A | — | 11 (best 0.76) |
Ligands
- MG · Magnesium ion · in 2 records
Experiment against prediction
- 1H2U chain B against the predicted model Q09161: TM-score 1.00, RMSD 0.37 Å
- 1H2U chain B against the predicted model Q09161: TM-score 1.00, RMSD 0.37 Å
- 1H6K chain C against the predicted model Q09161: TM-score 1.00, RMSD 0.47 Å
- 1H6K chain C against the predicted model Q09161: TM-score 1.00, RMSD 0.47 Å
- 1H6K chain B against the predicted model Q09161: TM-score 1.00, RMSD 0.50 Å
- 1H6K chain B against the predicted model Q09161: TM-score 1.00, RMSD 0.50 Å
- 1H2V chain C against the predicted model Q09161: TM-score 1.00, RMSD 0.50 Å
- 1H2V chain C against the predicted model Q09161: TM-score 1.00, RMSD 0.50 Å
- 1H2T chain C against the predicted model Q09161: TM-score 1.00, RMSD 0.50 Å
- 1H2T chain C against the predicted model Q09161: TM-score 1.00, RMSD 0.50 Å
Elsewhere
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