UniProt Q08188
Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain (Q08188)
Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain (UniProt Q08188): 13 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 28 pockets. Binding sites, druggability and experiment…
- UniProt
- Q08188
- Protein
- Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 28 · 3 records with a druggable one
Structures
14 records of Q08188 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1L9M | Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions change… | x-ray diffraction | A, B | — | — |
| 1L9M | Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions change… | x-ray diffraction | A, B | — | — |
| 1L9N | Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions change… | x-ray diffraction | A, B | — | — |
| 1L9N | Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions change… | x-ray diffraction | A, B | — | — |
| 1NUD | Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme (3 calciums… | x-ray diffraction | A, B | — | — |
| 1NUD | Role of calcium ions in the activation and activity of the transglutaminase 3 enzyme (3 calciums… | x-ray diffraction | A, B | — | — |
| 1NUF | Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme | x-ray diffraction | A | — | — |
| 1NUF | Role of calcium ions in the activation and activity of the transglutaminase 3 enzyme | x-ray diffraction | A | — | — |
| 1NUG | Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme (2 calciums, 1… | x-ray diffraction | A, B | — | — |
| 1NUG | Role of calcium ions in the activation and activity of the transglutaminase 3 enzyme (2 calciums, 1… | x-ray diffraction | A, B | — | — |
| 8OXW | Transglutaminase 3 in complex with DH patient-derived Fab DH63-B02 | x-ray diffraction | A | CA, CL | 9 (best 0.74) |
| 8OXX | Transglutaminase 3 in complex with inhibitor Z-don and DH patient-derived Fab DH63-B02 | x-ray diffraction | A | SO4, CA, P6S | 2 (best 0.47) |
| 8OXY | Transglutaminase 3 without calcium in complex with DH patient-derived Fab DH63-B02 | x-ray diffraction | A | PO4 | 11 (best 0.74) |
| Q08188 | AlphaFold monomer V2.0 prediction for protein-glutamine gamma- glutamyltransferase E (Q08188) | predicted | A | — | 6 (best 0.67) |
Ligands
Experiment against prediction
- 1L9N chain A against the predicted model Q08188: TM-score 1.00, RMSD 0.34 Å
- 1L9N chain A against the predicted model Q08188: TM-score 1.00, RMSD 0.34 Å
- 1NUD chain A against the predicted model Q08188: TM-score 1.00, RMSD 0.39 Å
- 1NUD chain A against the predicted model Q08188: TM-score 1.00, RMSD 0.39 Å
- 8OXW chain A against the predicted model Q08188: TM-score 1.00, RMSD 0.42 Å
- 1NUG chain A against the predicted model Q08188: TM-score 1.00, RMSD 0.55 Å
- 1NUG chain A against the predicted model Q08188: TM-score 1.00, RMSD 0.55 Å
- 1L9M chain A against the predicted model Q08188: TM-score 1.00, RMSD 0.57 Å
- 1L9M chain A against the predicted model Q08188: TM-score 1.00, RMSD 0.57 Å
- 1NUG chain B against the predicted model Q08188: TM-score 1.00, RMSD 0.60 Å
Elsewhere
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