UniProt Q07666
Isoform 2 of KH domain-containing, RNA-binding, signal transduction-associated protein 1 (Q07666)
Isoform 2 of KH domain-containing, RNA-binding, signal transduction-associated protein 1 (UniProt Q07666): 7 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 2 pockets. Binding sites, druggability and…
- UniProt
- Q07666
- Protein
- Isoform 2 of KH domain-containing, RNA-binding, signal transduction-associated…
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 2 · 0 records with a druggable one
Structures
8 records of Q07666 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2XA6 | Structural basis for homodimerization of the Src-associated during mitosis, 68 kD protein (Sam68)… | solution nmr | A, B | — | — |
| 2XA6 | Structural basis for homodimerization of the src-associated during mitosis, 68 kd protein (SAM68)… | solution nmr | A, B | — | — |
| 3QHE | Crystal structure of the complex between the armadillo repeat domain of adenomatous polyposis coli… | x-ray diffraction | B, D | — | — |
| 3QHE | Crystal structure of the complex between the armadillo repeat domain of adenomatous polyposis COLI… | x-ray diffraction | B, D | — | — |
| 7Z89 | Sam68 | x-ray diffraction | AAA, BBB | IOD, SO4 | 1 (best 0.50) |
| 7ZAB | Sam68 | x-ray diffraction | AAA | IOD, CL, LI | — |
| 7ZAM | Sam68 | x-ray diffraction | AAA, BBB | IOD, SO4 | 1 (best 0.34) |
| Q07666 | AlphaFold monomer V2.0 prediction for kh domain-containing, RNA- binding, signal… | predicted | A | — | — |
Ligands
Experiment against prediction
- 2XA6 chain A against the predicted model Q07666: TM-score 0.90, RMSD 0.62 Å
- 2XA6 chain A against the predicted model Q07666: TM-score 0.90, RMSD 0.62 Å
- 7ZAM chain BBB against the predicted model Q07666: TM-score 0.89, RMSD 1.74 Å
- 7ZAB chain AAA against the predicted model Q07666: TM-score 0.88, RMSD 1.50 Å
- 7ZAM chain AAA against the predicted model Q07666: TM-score 0.88, RMSD 1.50 Å
- 7Z89 chain AAA against the predicted model Q07666: TM-score 0.88, RMSD 1.61 Å
- 7Z89 chain BBB against the predicted model Q07666: TM-score 0.88, RMSD 1.64 Å
- 3QHE chain D against the predicted model Q07666: TM-score 0.39, RMSD 1.43 Å
- 3QHE chain D against the predicted model Q07666: TM-score 0.39, RMSD 1.43 Å
- 3QHE chain B against the predicted model Q07666: TM-score 0.35, RMSD 1.93 Å
Elsewhere
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