UniProt Q02753
60S ribosomal protein L21-A (Q02753)
60S ribosomal protein L21-A (UniProt Q02753): 99 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 79 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q02753
- Protein
- 60S ribosomal protein L21-A
- Experimental structures
- 99
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 79 · 39 records with a druggable one
Structures
100 records of Q02753 in the MolNFT archive: 99 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3J6X | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II) | electron microscopy | 61 | — | — |
| 3J6Y | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I) | electron microscopy | 61 | — | — |
| 3J77 | Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class… | electron microscopy | 71 | — | — |
| 3J78 | Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class… | electron microscopy | 71 | — | — |
| 3JCT | Cryo-em structure of eukaryotic pre-60S ribosomal subunits | electron microscopy | T | — | — |
| 4U3M | Crystal structure of Anisomycin bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U3N | Crystal structure of CCA trinucleotide bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U3U | Crystal structure of Cycloheximide bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U4N | Crystal structure of Edeine bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U4O | Crystal structure of Geneticin bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U4Q | Crystal structure of Homoharringtonine bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U4R | Crystal structure of Lactimidomycin bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U4U | Crystal structure of Lycorine bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U4Y | Crystal structure of Pactamycin bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U4Z | Crystal structure of Phyllanthoside bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U50 | Crystal structure of Verrucarin bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U51 | Crystal structure of Narciclasine bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U52 | Crystal structure of Nagilactone C bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U53 | Crystal structure of Deoxynivalenol bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U55 | Crystal structure of Cryptopleurine bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U56 | Crystal structure of Blasticidin S bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4U6F | Crystal structure of T-2 toxin bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | — | — |
| 4V4B | Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models… | electron microscopy | BQ | — | — |
| 4V6I | Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces… | electron microscopy | BU | — | — |
| 4V7F | Arx1 pre-60S particle. | electron microscopy | T | — | — |
| 4V7F | ARX1 pre-60S particle. | electron microscopy | T | — | — |
| 4V7R | Yeast 80S ribosome. | x-ray diffraction | BT, DT | — | — |
| 4V88 | The structure of the eukaryotic ribosome at 3.0 A resolution. | x-ray diffraction | BT, DT | — | — |
| 4V8T | Cryo-EM Structure of the 60S Ribosomal Subunit in Complex with Arx1 and Rei1 | electron microscopy | T | — | — |
| 4V8Y | Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex | electron microscopy | BT | — | — |
| 4V8Z | Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex | electron microscopy | BT | — | — |
| 5FCI | Structure of the vacant uL3 W255C mutant 80S yeast ribosome | x-ray diffraction | N1, n1 | OHX, MG | 1 (best 0.87) |
| 5GAK | Yeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5A | electron microscopy | V | — | 2 (best 0.88) |
| 5H4P | Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1 | electron microscopy | T | — | — |
| 5JCS | Cryo-EM structure of the RIX1-REA1 pre-60S particle | electron microscopy | T | — | 1 (best 0.79) |
| 5JUP | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | Y | — | — |
| 5JUS | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | Y | — | — |
| 5JUU | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | Y | — | 3 (best 0.88) |
| 5M1J | Nonstop ribosomal complex bound with Dom34 and Hbs1 | electron microscopy | T5 | MG | 1 (best 0.85) |
| 5MC6 | Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae | electron microscopy | BJ | — | — |
| 5MEI | Crystal structure of Agelastatin A bound to the 80S ribosome | x-ray diffraction | 2, CV | MG, OHX | — |
| 5NDG | Crystal structure of geneticin (G418) bound to the yeast 80S ribosome | x-ray diffraction | N1, n1 | MG | 3 (best 0.88) |
| 5T6R | Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome… | electron microscopy | g | — | 4 (best 0.88) |
| 6ELZ | State E (TAP-Flag-Ytm1 E80A) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | electron microscopy | T | — | 1 (best 0.85) |
| 6EM5 | State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar… | electron microscopy | T | — | — |
| 6EM5 | State D architectural model (NSA1-tap flag-YTM1) - visualizing the assembly pathway of nucleolar… | electron microscopy | T | — | — |
| 6GQ1 | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP/sordarin) | electron microscopy | T | — | — |
| 6GQB | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GDP+AlF4/sordarin) | electron microscopy | T | — | — |
| 6GQV | Cryo-EM recosntruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP) | electron microscopy | T | — | — |
| 6HD7 | Cryo-EM structure of the ribosome-NatA complex | electron microscopy | V | — | — |
| 6HHQ | Crystal structure of compound C45 bound to the yeast 80S ribosome | x-ray diffraction | 2, CV | MG, OHX | — |
| 6I7O | The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways… | electron microscopy | BJ, YJ | — | — |
| 6M62 | Cryo-Em structure of eukaryotic pre-60S ribosome subunit from Saccharomyces cerevisiae rpf2 delta… | electron microscopy | T | — | — |
| 6N8J | Cryo-EM structure of late nuclear (LN) pre-60S ribosomal subunit | electron microscopy | T | — | 1 (best 0.86) |
| 6N8K | Cryo-EM structure of early cytoplasmic-immediate (ECI) pre-60S ribosomal subunit | electron microscopy | T | — | — |
| 6N8L | Cryo-EM structure of early cytoplasmic-late (ECL) pre-60S ribosomal subunit | electron microscopy | T | — | — |
| 6N8M | Cryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunit | electron microscopy | g | — | — |
| 6N8N | Cryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunit | electron microscopy | g | — | — |
| 6N8O | Cryo-EM structure of Rpl10-inserted (RI) pre-60S ribosomal subunit | electron microscopy | g | — | — |
| 6Q8Y | Cryo-EM structure of the mRNA translating and degrading yeast 80S ribosome-Xrn1 nuclease complex | electron microscopy | BJ | — | 2 (best 0.87) |
40 records more on the page itself.
Ligands
Experiment against prediction
- 8BN3 chain N1 against the predicted model Q02753: TM-score 0.97, RMSD 0.80 Å
- 8AGW chain G against the predicted model Q02753: TM-score 0.97, RMSD 0.93 Å
- 8AGZ chain G against the predicted model Q02753: TM-score 0.97, RMSD 0.93 Å
- 5NDG chain n1 against the predicted model Q02753: TM-score 0.97, RMSD 0.93 Å
- 5NDG chain N1 against the predicted model Q02753: TM-score 0.97, RMSD 0.96 Å
- 8CIV chain F against the predicted model Q02753: TM-score 0.97, RMSD 0.92 Å
- 4U6F chain N1 against the predicted model Q02753: TM-score 0.97, RMSD 0.96 Å
- 6Z6J chain LT against the predicted model Q02753: TM-score 0.97, RMSD 0.93 Å
- 4U4U chain N1 against the predicted model Q02753: TM-score 0.97, RMSD 0.97 Å
- 4U52 chain N1 against the predicted model Q02753: TM-score 0.97, RMSD 0.96 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.