UniProt Q02554
Cold sensitive U2 snRNA suppressor 1 (Q02554)
Cold sensitive U2 snRNA suppressor 1 (UniProt Q02554): 15 experimental structures and 1 predicted model on GenesisL1, 40 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q02554
- Protein
- Cold sensitive U2 snRNA suppressor 1
- Experimental structures
- 15
- Predicted models
- 1
- Pockets
- 40 · 13 records with a druggable one
Structures
16 records of Q02554 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GM6 | Cryo-EM structure of the activated spliceosome (Bact complex) at 3.5 angstrom resolution | electron microscopy | H | — | 1 (best 0.87) |
| 5LSB | Crystal structure of yeast Hsh49p in complex with Cus1p binding domain. | x-ray diffraction | B, D, H | — | — |
| 5LSB | Crystal structure of yeast HSH49P in complex with CUS1P binding domain. | x-ray diffraction | B, D, H | — | — |
| 5LSL | Crystal structure of yeast Hsh49p in complex with Cus1p binding domain. | x-ray diffraction | E, F, H, G | — | 5 (best 0.70) |
| 5LSL | Crystal structure of yeast HSH49P in complex with CUS1P binding domain. | x-ray diffraction | E, F, H, G | — | 5 (best 0.70) |
| 5NRL | Structure of a pre-catalytic spliceosome | electron microscopy | Q | — | 2 (best 0.87) |
| 5ZWM | Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom… | electron microscopy | 2 | — | 3 (best 0.85) |
| 5ZWO | Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom | electron microscopy | 2 | — | 2 (best 0.85) |
| 5ZWO | Cryo-EM structure of the yeast B complex at average resolution of 3.9 ångström | electron microscopy | 2 | — | 2 (best 0.85) |
| 6G90 | Prespliceosome structure provides insight into spliceosome assembly and regulation (map A2) | electron microscopy | Q | — | 2 (best 0.84) |
| 6G90 | Prespliceosome structure provides insight into spliceosome assembly and regulation (MAP A2) | electron microscopy | Q | — | 2 (best 0.84) |
| 7OQB | The U2 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | electron microscopy | Q | — | 4 (best 0.80) |
| 7OQB | The U2 part of saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) | electron microscopy | Q | — | 4 (best 0.80) |
| 7OQE | Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | electron microscopy | Q | — | 3 (best 0.82) |
| 7OQE | Saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) | electron microscopy | Q | — | 3 (best 0.82) |
| Q02554 | AlphaFold monomer V2.0 prediction for cold sensitive U2 snrna suppressor 1 (Q02554) | predicted | A | — | 2 (best 0.39) |
Experiment against prediction
- 5LSL chain H against the predicted model Q02554: TM-score 0.99, RMSD 0.28 Å
- 5LSL chain H against the predicted model Q02554: TM-score 0.99, RMSD 0.28 Å
- 5LSL chain G against the predicted model Q02554: TM-score 0.99, RMSD 0.31 Å
- 5LSL chain G against the predicted model Q02554: TM-score 0.99, RMSD 0.31 Å
- 5LSL chain F against the predicted model Q02554: TM-score 0.98, RMSD 0.41 Å
- 5LSL chain F against the predicted model Q02554: TM-score 0.98, RMSD 0.41 Å
- 5LSB chain H against the predicted model Q02554: TM-score 0.98, RMSD 0.39 Å
- 5LSB chain H against the predicted model Q02554: TM-score 0.98, RMSD 0.39 Å
- 5LSL chain E against the predicted model Q02554: TM-score 0.98, RMSD 0.40 Å
- 5LSL chain E against the predicted model Q02554: TM-score 0.98, RMSD 0.40 Å
Elsewhere
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