UniProt Q01974
Tyrosine-protein kinase transmembrane receptor ROR2 (Q01974)
Tyrosine-protein kinase transmembrane receptor ROR2 (UniProt Q01974), EC 2.7.10.1: 12 experimental structures on GenesisL1, 1 ligand bound, 4 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q01974
- Protein
- Tyrosine-protein kinase transmembrane receptor ROR2
- EC
- 2.7.10.1
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
12 records of Q01974 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3ZZW | Crystal structure of the kinase domain of ROR2 | x-ray diffraction | A, B | — | — |
| 3ZZW | Crystal structure of the kinase domain of ROR2 | x-ray diffraction | A, B | — | — |
| 4GT4 | Structure of unliganded, inactive Ror2 kinase domain | x-ray diffraction | A, B | — | — |
| 4GT4 | Structure of unliganded, inactive ROR2 kinase domain | x-ray diffraction | A, B | — | — |
| 6OSH | Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2 | x-ray diffraction | K | — | 1 (best 0.38) |
| 6OSH | Potent and selective antitumor antibody targeting a membrane-proximal epitope of ROR2 | x-ray diffraction | K | — | — |
| 6OSN | Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2 | x-ray diffraction | A | — | — |
| 6OSN | Potent and selective antitumor antibody targeting a membrane-proximal epitope of ROR2 | x-ray diffraction | A | — | — |
| 6OSV | Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2 | x-ray diffraction | K | — | 1 (best 0.44) |
| 6OSV | Potent and selective antitumor antibody targeting a membrane-proximal epitope of ROR2 | x-ray diffraction | K | — | — |
| 9FSE | Human ROR2 cysteine-rich domain (CRD) and Kringle domain | x-ray diffraction | A | SO4 | 2 (best 0.58) |
| Q01974 | AlphaFold monomer V2.0 prediction for tyrosine-protein kinase transmembrane receptor ROR2 (Q01974) | — | — | — |
Ligands
- SO4 · Sulfate ion · in 1 record
Elsewhere
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