MolNFT v1 · #159536 · protein
Potent and selective antitumor antibody targeting a membrane-proximal epitope of ROR2
6OSN · Tyrosine-protein kinase transmembrane receptor ROR2: “Potent and selective antitumor antibody targeting a membrane-proximal epitope of ROR2”. X-ray diffraction. MolNFT v1 #159536 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 6OSN
- Type
- protein
- Length
- 85 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tyrosine-protein kinase transmembrane receptor ROR2
- EC
- 2.7.10.1
- UniProt
- Q01974
Structure
x-ray diffraction · 1 distinct chain · 7% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosine-protein kinase transmembrane receptor ROR2 (EC 2.7.10.1) | protein | 85 | 7% helix, 18% strand | Q01974 |
Ligands and binding sites
- ACT · Acetate ion · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 6OSN · Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2 · the same entry in another collection · chain A against A, TM-score 1.00
- Q01974 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase transmembrane receptor ROR2… · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q01974
- Elsewhere: RCSB PDB 6OSN · PDBe 6OSN · UniProt Q01974
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