UniProt P96202
Phthiocerol synthesis polyketide synthase type I PpsC (P96202)
Phthiocerol synthesis polyketide synthase type I PpsC (UniProt P96202), EC 2.3.1.292, 2.3.1.41: 15 experimental structures on GenesisL1, 6 ligands bound, 13 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P96202
- Protein
- Phthiocerol synthesis polyketide synthase type I PpsC
- EC
- 2.3.1.292, 2.3.1.41
- Experimental structures
- 15
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 13 · 4 records with a druggable one
Structures
15 records of P96202 in the MolNFT archive: 15 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PQW | Putative enoyl reductase domain of polyketide synthase | x-ray diffraction | A, B | — | — |
| 1PQW | Putative enoyl reductase domain of polyketide synthase | x-ray diffraction | A, B | — | — |
| 4OKI | X-ray structure of the nucleotide-binding subdomain of the enoylreductase domain of PpsC from… | x-ray diffraction | A, B | — | — |
| 4OKI | X-ray structure of the nucleotide-binding subdomain of the enoylreductase domain of ppsc from… | x-ray diffraction | A, B | — | — |
| 4OOC | Dehydratase domain of the polyketide PpsC from Mycobacterium tuberculosis | x-ray diffraction | A | — | — |
| 4OOC | Dehydratase domain of the polyketide ppsc from mycobacterium tuberculosis | x-ray diffraction | A | — | — |
| 5I0K | Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases | x-ray diffraction | A | COO | 1 (best 0.75) |
| 5I0K | Insights into substrate modification by dehydratases from type I polyketide synthases | x-ray diffraction | A | — | — |
| 5L84 | Structure of the H959F variant of the PpsC dehydratase domain from Mycobacterium tuberculosis | x-ray diffraction | A | — | 1 (best 0.73) |
| 5L84 | Structure of the H959F variant of the ppsc dehydratase domain from mycobacterium tuberculosis | x-ray diffraction | A | — | — |
| 6RCX | Mycobacterial 4'-phosphopantetheinyl transferase pptab in complex with the acp domain of ppsc. | x-ray diffraction | B | COA, MN | — |
| 7AHB | Acyltransferase domain of the polyketide synthase PpsC of Mycobacterium tuberculosis | x-ray diffraction | A, B | SO4, SCN, NA | 7 (best 0.73) |
| 7AHB | Acyltransferase domain of the polyketide synthase ppsc of mycobacterium tuberculosis | x-ray diffraction | A, B | SO4, SCN, NA | — |
| 8QZI | Crystal structure of PptT-ACP from Mycobacterium tuberculosis | x-ray diffraction | E, F | MN, COA | 4 (best 0.81) |
| P96202 | AlphaFold monomer V2.0 prediction for PHENOLPHTHIOCEROL/PHTHIOCEROL polyketide synthase subunit C… | — | — | — |
Ligands
Elsewhere
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