UniProt P93819
Malate dehydrogenase 1, cytoplasmic (P93819)
Malate dehydrogenase 1, cytoplasmic (UniProt P93819), EC 1.1.1.37: 4 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 46 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P93819
- Protein
- Malate dehydrogenase 1, cytoplasmic
- EC
- 1.1.1.37
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 46 · 5 records with a druggable one
Structures
5 records of P93819 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5NUE | Cytosolic Malate Dehydrogenase 1 (peroxide-treated) | x-ray diffraction | A, B, C | NAD, SO4, PEO, ETX | 10 (best 0.73) |
| 5NUE | Cytosolic malate dehydrogenase 1 (peroxide-treated) | x-ray diffraction | A, B, C | NAD, SO4, PEO, ETX | 10 (best 0.73) |
| 5NUF | Cytosolic Malate Dehydrogenase 1 | x-ray diffraction | A, B, C | NAD, SO4, PEO, NA | 12 (best 0.79) |
| 5NUF | Cytosolic malate dehydrogenase 1 | x-ray diffraction | A, B, C | NAD, SO4, PEO, NA | 12 (best 0.79) |
| P93819 | AlphaFold monomer V2.0 prediction for malate dehydrogenase 1, cytoplasmic (P93819) | predicted | A | — | 2 (best 0.63) |
Ligands
Experiment against prediction
- 5NUF chain A against the predicted model P93819: TM-score 0.98, RMSD 0.93 Å
- 5NUF chain A against the predicted model P93819: TM-score 0.98, RMSD 0.93 Å
- 5NUF chain B against the predicted model P93819: TM-score 0.98, RMSD 0.93 Å
- 5NUF chain B against the predicted model P93819: TM-score 0.98, RMSD 0.93 Å
- 5NUE chain C against the predicted model P93819: TM-score 0.98, RMSD 0.98 Å
- 5NUE chain C against the predicted model P93819: TM-score 0.98, RMSD 0.98 Å
- 5NUE chain A against the predicted model P93819: TM-score 0.98, RMSD 0.96 Å
- 5NUE chain A against the predicted model P93819: TM-score 0.98, RMSD 0.96 Å
- 5NUE chain B against the predicted model P93819: TM-score 0.96, RMSD 1.78 Å
- 5NUE chain B against the predicted model P93819: TM-score 0.96, RMSD 1.78 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.