GL1X · GenesisL1 explorer

Ligand · ETX

ETX · 2-ethoxyethanol

ETX, 2-ethoxyethanol (C4 H10 O2, 90.1 g/mol), in the MolNFT structures on GenesisL1: bound in 26 records (16 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
ETX
Formula
C4 H10 O2
Class
ligand
Structures
26
PDB entries
16

Binding sites

ETX in 26 structures; the first of them:

  • 5LTE · Crystal structure of the alpha subunit of heme dependent oxidative N-demethylase (HODM) · ETX A502 · binds GLU33, MET37, SER39
  • 5NUE · Cytosolic Malate Dehydrogenase 1 (peroxide-treated) · ETX A411 · binds GLN167, GLU170, ARG231, SME56, ILE59
  • 5OIC · InhA (T2A mutant) complexed with (4-((1H-pyrazol-1-yl)methyl)phenyl)methanol · ETX A303 · binds SER19, HIS24, ARG27, ILE194, ARG195, LYS233, ASP234, ALA235 and 1 more
  • 5OIM · InhA (T2A mutant) complexed with ethyl 2-methyl-4,5,6,7-tetrahydrobenzo[d]thiazole-6-carbo… · ETX A303 · binds SER19, HIS24, ILE194, LYS233, ASP234, ALA235, THR236
  • 5OIR · InhA (T2A mutant) complexed with 2,6-Dimethyl-3-(1-(pyrimidin-2-yl)piperidin-4-yl)pyridin… · ETX A303 · binds MET103, GLY104, PHE149, MET155, ALA157, TYR158, ILE202, LEU207 and 2 more
  • 6CJ6 · Structure of the poxvirus protein F9 · ETX A250 · binds LYS8, ILE166
  • 6HB8 · Crystal structure of OXA-517 beta-lactamase · ETX A303 · binds VAL92, ARG107, ASP108, HIS109, ASN110, THR113, ASP229, ASP230
  • 6V4C · Culex quinquefasciatus D7 long form 1- CxD7L1 in complex with ADP · ETX A306 · binds GLU292
  • 7AEZ · Crystal structure of the metallo-beta-lactamase NDM-7 with 407 · ETX A308 · binds PRO150, GLN151, GLY153
  • 7MP0 · Crystal structure of native bovine arrestin 1 in complex with 1D-myo-inositol… · ETX A501 · binds VAL259, ALA260, ALA261, GLU262, ASN286
  • 7U1N · Crystal structure of the Anopheles darlingi AD-118 long form D7 salivary protein · ETX A301 · binds ASN220, ARG221, GLY222, ASP223, GLU22, HIS23, HIS48, CYS52
  • 8BXU · Crystal structure of Odorant Binding Protein 5 from Anopheles gambiae (AgamOBP5) with MPD… · ETX AAA205 · binds ASP12, ARG15, ASP30, ARG33
  • 5LTE · Crystal structure of the alpha subunit of heme dependent oxidative N- demethylase (hodm) · ETX A502 · binds GLU33, MET37, SER39
  • 5NUE · Cytosolic malate dehydrogenase 1 (peroxide-treated) · ETX A411 · binds GLN167, GLU170, ARG231, SME56, ILE59
  • 5OIC · Inha (T2A mutant) complexed with (4-((1H-pyrazol-1-YL)METHYL)PHENYL) methanol · ETX A303 · binds SER19, HIS24, ILE194, LYS233, ASP234, ALA235, THR236
  • 5OIL · Inha (T2A mutant) complexed with 1-cyclohexyl-3-(pyridin-3-ylmethyl) urea · ETX A303 · binds SER19, HIS24, ARG195, LYS233, ASP234, ALA235
  • 5OIM · Inha (T2A mutant) complexed with ethyl 2-methyl-4,5,6,7… · ETX A303 · binds SER19, HIS24, ILE194, LYS233, ASP234, ALA235, THR236
  • 5OIR · Inha (T2A mutant) complexed with 2,6-dimethyl-3-(1-(pyrimidin-2-yl)… · ETX A303 · binds MET103, GLY104, PHE149, MET155, ALA157, TYR158, ILE202, LEU207 and 2 more

Residues it binds most

SER 24, ARG 19, ASP 17, LYS 18, ILE 16, GLU 17, ALA 13, HIS 10, LEU 10, THR 12 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • GOL · Glycerol
  • NAD · Nicotinamide-adenine-dinucleotide
  • SO4 · Sulfate ion
  • PEG · Di(hydroxyethyl)ether
  • NA · Sodium ion
  • PG0 · 2-(2-methoxyethoxy)ethanol
  • ZN · Zinc ion
  • PGE · Triethylene glycol
  • 9VQ · [4-(pyrazol-1-ylmethyl)phenyl]methanol
  • 9VZ · ethyl (6~{R})-2-methyl-4,5,6,7-tetrahydro-1,3-benzothiazole-6-carboxylate
  • 9W8 · 2,6-dimethyl-3-(1-pyrimidin-2-ylpiperidin-4-yl)-1~{H}-pyridin-4-one

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