UniProt P93031
GDP-D-mannose-4,6-dehydratase (P93031)
GDP-D-mannose-4,6-dehydratase (UniProt P93031), EC 4.2.1.47: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P93031
- Protein
- GDP-D-mannose-4,6-dehydratase
- EC
- 4.2.1.47
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 12 · 2 records with a druggable one
Structures
5 records of P93031 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1N7G | Crystal Structure of the GDP-mannose 4,6-dehydratase ternary complex with NADPH and GDP-rhamnose. | x-ray diffraction | A, B, C, D | NDP, GDR | 9 (best 0.91) |
| 1N7G | Crystal structure of the GDP-mannose 4,6-dehydratase ternary complex with NADPH and GDP-rhamnose. | x-ray diffraction | A, B, C, D | — | — |
| 1N7H | Crystal Structure of GDP-mannose 4,6-dehydratase ternary complex with NADPH and GDP | x-ray diffraction | A, B | NDP, GDP | 3 (best 0.81) |
| 1N7H | Crystal structure of GDP-mannose 4,6-dehydratase ternary complex with NADPH and GDP | x-ray diffraction | A, B | — | — |
| P93031 | AlphaFold monomer V2.0 prediction for GDP-mannose 4,6 dehydratase 2 (P93031) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1N7H chain A against the predicted model P93031: TM-score 1.00, RMSD 0.43 Å
- 1N7H chain A against the predicted model P93031: TM-score 1.00, RMSD 0.43 Å
- 1N7H chain B against the predicted model P93031: TM-score 1.00, RMSD 0.48 Å
- 1N7H chain B against the predicted model P93031: TM-score 1.00, RMSD 0.48 Å
- 1N7G chain A against the predicted model P93031: TM-score 0.99, RMSD 0.55 Å
- 1N7G chain A against the predicted model P93031: TM-score 0.99, RMSD 0.55 Å
- 1N7G chain C against the predicted model P93031: TM-score 0.99, RMSD 0.70 Å
- 1N7G chain C against the predicted model P93031: TM-score 0.99, RMSD 0.70 Å
- 1N7G chain B against the predicted model P93031: TM-score 0.99, RMSD 0.74 Å
- 1N7G chain B against the predicted model P93031: TM-score 0.99, RMSD 0.74 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.