UniProt P92507
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (P92507)
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (UniProt P92507): 23 experimental structures and 1 predicted model on GenesisL1, 13 ligands bound, 222 pockets. Binding sites, druggability and…
- UniProt
- P92507
- Protein
- Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial
- Experimental structures
- 23
- Predicted models
- 1
- Ligands
- 13
- Pockets
- 222 · 23 records with a druggable one
Structures
24 records of P92507 in the MolNFT archive: 23 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3VR8 | Mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode Ascaris suum | x-ray diffraction | D, H | HEM, RQX, EPH | 10 (best 0.85) |
| 3VR8 | Mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode ascaris suum | x-ray diffraction | D, H | HEM, RQX, EPH | 10 (best 0.85) |
| 3VR9 | Mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode Ascaris suum with the… | x-ray diffraction | D, H | HEM, FTN, EPH | 10 (best 0.85) |
| 3VR9 | Mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode ascaris suum with the… | x-ray diffraction | D, H | HEM, FTN, EPH | 10 (best 0.85) |
| 3VRA | Mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode Ascaris suum with the… | x-ray diffraction | D, H | HEM, AT5, EPH | 9 (best 0.86) |
| 3VRA | Mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode ascaris suum with the… | x-ray diffraction | D, H | HEM, AT5, EPH | 9 (best 0.86) |
| 3VRB | Mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode Ascaris suum with the… | x-ray diffraction | D, H | HEM, FTN, EPH | 11 (best 0.86) |
| 3VRB | Mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode ascaris suum with the… | x-ray diffraction | D, H | HEM, FTN, EPH | 11 (best 0.86) |
| 4YSX | Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with the… | x-ray diffraction | D, H | E23, HEM, EPH | 10 (best 0.86) |
| 4YSX | Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with the… | x-ray diffraction | D, H | E23, HEM, EPH | 10 (best 0.86) |
| 4YSY | Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with… | x-ray diffraction | D, H | E24, HEM, EPH | 8 (best 0.86) |
| 4YSY | Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with… | x-ray diffraction | D, H | E24, HEM, EPH | 8 (best 0.86) |
| 4YSZ | Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with… | x-ray diffraction | D, H | HEM, 12J, EPH | 8 (best 0.86) |
| 4YSZ | Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with… | x-ray diffraction | D, H | HEM, 12J, EPH | 8 (best 0.86) |
| 4YT0 | Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with… | x-ray diffraction | D, H | HEM, MRN | 9 (best 0.86) |
| 4YT0 | Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with… | x-ray diffraction | D, H | HEM, MRN | 9 (best 0.86) |
| 4YTM | Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with… | x-ray diffraction | D, H | HEM, F6A, EPH | 11 (best 0.86) |
| 4YTM | Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with… | x-ray diffraction | D, H | HEM, F6A, EPH | 11 (best 0.86) |
| 4YTN | Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with… | x-ray diffraction | D, H | HEM, FD8 | 10 (best 0.86) |
| 4YTN | Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with… | x-ray diffraction | D, H | HEM, FD8 | 10 (best 0.86) |
| 5C2T | Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with rhodoqui -2 | x-ray diffraction | D, H | HEM, 4YP, EPH | 10 (best 0.86) |
| 5C2T | Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with… | x-ray diffraction | D, H | HEM, 4YP, EPH | 10 (best 0.86) |
| 5C3J | Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with… | x-ray diffraction | D, H | HEM, UQ1, EPH | 10 (best 0.85) |
| P92507 | AlphaFold monomer V2.0 prediction for succinate dehydrogenase [ubiquinone] cytochrome B small… | predicted | A | — | — |
Ligands
- HEM · Protoporphyrin IX containing Fe · in 23 records
- EPH · L-alpha-phosphatidyl-beta-oleoyl-gamma-palmitoyl-phosphatidylethanolamine · in 19 records
- FTN · N-[3-(1-methylethoxy)phenyl]-2-(trifluoromethyl) benzamide · in 4 records
- 12J · 2-iodo-N-[3-(1-methylethoxy)phenyl]benzamide · in 2 records
- 4YP · 2-amino-5-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-methoxy-6-methylcyclohexa-2,5-diene-1,4-dione · in 2 records
- AT5 · 3-[(2S,4S,5R)-5,6-dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1H)-pyridinone · in 2 records
- E23 · N-(4-tert-butylbenzyl)-2-(trifluoromethyl)benzamide · in 2 records
- E24 · N-(2,4-dichlorobenzyl)-2-(trifluoromethyl)benzamide · in 2 records
- F6A · N-biphenyl-3-yl-2-(trifluoromethyl)benzamide · in 2 records
- FD8 · N-[3-(pentafluorophenoxy)phenyl]-2-(trifluoromethyl)benzamide · in 2 records
- MRN · 2-methyl-N-[3-(1-methylethoxy)phenyl]benzamide · in 2 records
- RQX · 2-amino-3-methoxy-6-methyl-5-[(2E)-3-methylhex-2-en-1-yl]cyclohexa-2,5-diene-1,4-dione · in 2 records
- UQ1 · Ubiquinone-1 · in 1 record
Experiment against prediction
- 5C3J chain H against the predicted model P92507: TM-score 0.90, RMSD 1.81 Å
- 5C2T chain H against the predicted model P92507: TM-score 0.90, RMSD 1.58 Å
- 5C2T chain H against the predicted model P92507: TM-score 0.90, RMSD 1.58 Å
- 4YTM chain H against the predicted model P92507: TM-score 0.89, RMSD 1.78 Å
- 4YTM chain H against the predicted model P92507: TM-score 0.89, RMSD 1.78 Å
- 4YTN chain H against the predicted model P92507: TM-score 0.89, RMSD 1.61 Å
- 4YTN chain H against the predicted model P92507: TM-score 0.89, RMSD 1.61 Å
- 4YT0 chain H against the predicted model P92507: TM-score 0.89, RMSD 1.61 Å
- 4YT0 chain H against the predicted model P92507: TM-score 0.89, RMSD 1.61 Å
- 4YSZ chain H against the predicted model P92507: TM-score 0.89, RMSD 1.60 Å
Elsewhere
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