UniProt P84243
Histone H3.3 (P84243)
Histone H3.3 (UniProt P84243): 130 experimental structures and 1 predicted model on GenesisL1, 10 ligands bound, 105 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P84243
- Protein
- Histone H3.3
- Experimental structures
- 130
- Predicted models
- 1
- Ligands
- 10
- Pockets
- 105 · 23 records with a druggable one
Structures
131 records of P84243 in the MolNFT archive: 130 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2L43 | Structural basis for histone code recognition by BRPF2-PHD1 finger | solution nmr | A | — | — |
| 2L43 | Structural basis for histone code recognition by BRPF2-PHD1 finger | solution nmr | A | — | — |
| 3ASK | Structure of UHRF1 in complex with histone tail | x-ray diffraction | P, Q, R | — | — |
| 3ASK | Structure of UHRF1 in complex with histone tail | x-ray diffraction | P, Q, R | — | — |
| 3ASL | Structure of UHRF1 in complex with histone tail | x-ray diffraction | B | — | — |
| 3ASL | Structure of UHRF1 in complex with histone tail | x-ray diffraction | B | — | — |
| 3AV2 | The human nucleosome structure containing the histone variant H3.3 | x-ray diffraction | A, E | — | — |
| 3AV2 | The human nucleosome structure containing the histone variant H3.3 | x-ray diffraction | A, E | — | — |
| 3JVK | Crystal structure of bromodomain 1 of mouse Brd4 in complex with histone H3-K(ac)14 | x-ray diffraction | C | — | — |
| 3JVK | Crystal structure of bromodomain 1 of mouse BRD4 in complex with histone H3-K(AC)14 | x-ray diffraction | C | — | — |
| 3MUK | Crystal structure of Brd4 bromodomain 1 with propionylated histone H3-K(prop)23 | x-ray diffraction | D | — | — |
| 3MUK | Crystal structure of BRD4 bromodomain 1 with propionylated histone H3- K(PROP)23 | x-ray diffraction | D | — | — |
| 3MUL | Crystal structure of Brd4 bromodomain 1 with butyrylated histone H3-K(buty)14 | x-ray diffraction | D | — | — |
| 3MUL | Crystal structure of BRD4 bromodomain 1 with butyrylated histone H3- K(BUTY)14 | x-ray diffraction | D | — | — |
| 3QL9 | Monoclinic complex structure of ATRX ADD bound to histone H3K9me3 peptide | x-ray diffraction | C | — | — |
| 3QL9 | Monoclinic complex structure of atrx add bound to histone H3K9ME3 peptide | x-ray diffraction | C | — | — |
| 3QLA | Hexagonal complex structure of ATRX ADD bound to H3K9me3 peptide | x-ray diffraction | C, F | — | — |
| 3QLA | Hexagonal complex structure of atrx add bound to H3K9ME3 peptide | x-ray diffraction | C, F | — | — |
| 3QLC | Complex structure of ATRX ADD domain bound to unmodified H3 1-15 peptide | x-ray diffraction | C, D | — | — |
| 3QLC | Complex structure of atrx add domain bound to unmodified H3 1-15 peptide | x-ray diffraction | C, D | — | — |
| 3WTP | Crystal Structure of the heterotypic nucleosome containing human CENP-A and H3.3 | x-ray diffraction | E | — | — |
| 3WTP | Crystal structure of the heterotypic nucleosome containing human cenp- a and H3.3 | x-ray diffraction | E | — | — |
| 4GNE | Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-7 | x-ray diffraction | B | — | — |
| 4GNE | Crystal structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-7 | x-ray diffraction | B | — | — |
| 4GNF | Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-15 | x-ray diffraction | C | — | — |
| 4GNF | Crystal structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-15 | x-ray diffraction | C | — | — |
| 4GNG | Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3K9me3 peptide | x-ray diffraction | B, F | — | — |
| 4GNG | Crystal structure of NSD3 tandem PHD5-C5HCH domains complexed with H3K9ME3 peptide | x-ray diffraction | B, F | — | — |
| 4GU0 | Crystal structure of LSD2 with H3 | x-ray diffraction | E, F | — | — |
| 4GU0 | Crystal structure of LSD2 with H3 | x-ray diffraction | E, F | — | — |
| 4GUR | Crystal structure of LSD2-NPAC with H3 in space group P21 | x-ray diffraction | C | — | — |
| 4GUR | Crystal structure of LSD2-npac with H3 in space group P21 | x-ray diffraction | C | — | — |
| 4GUS | Crystal structure of LSD2-NPAC with H3 in space group P3221 | x-ray diffraction | C | — | — |
| 4GUS | Crystal structure of LSD2-npac with H3 in space group P3221 | x-ray diffraction | C | — | — |
| 4GY5 | Crystal structure of the tandem tudor domain and plant homeodomain of UHRF1 with Histone H3K9me3 | x-ray diffraction | E, F | — | — |
| 4GY5 | Crystal structure of the tandem tudor domain and plant homeodomain of UHRF1 with histone H3K9ME3 | x-ray diffraction | E, F | — | — |
| 4H9N | Complex structure 1 of DAXX/H3.3(sub5)/H4 | x-ray diffraction | A | — | — |
| 4H9N | Complex structure 1 of DAXX/H3.3(SUB5)/H4 | x-ray diffraction | A | — | — |
| 4H9O | Complex structure 2 of DAXX/H3.3(sub5,G90M)/H4 | x-ray diffraction | A | — | — |
| 4H9O | Complex structure 2 of DAXX/H3.3(SUB5,G90M)/H4 | x-ray diffraction | A | — | — |
| 4H9P | Complex structure 3 of DAXX/H3.3(sub5,G90A)/H4 | x-ray diffraction | A | — | — |
| 4H9P | Complex structure 3 of DAXX/H3.3(SUB5,G90A)/H4 | x-ray diffraction | A | — | — |
| 4H9Q | Complex structure 4 of DAXX(E225A)/H3.3(sub5)/H4 | x-ray diffraction | A | — | — |
| 4H9Q | Complex structure 4 of DAXX(E225A)/H3.3(SUB5)/H4 | x-ray diffraction | A | — | — |
| 4H9R | Complex structure 5 of DAXX(E225A)/H3.3(sub5,G90A)/H4 | x-ray diffraction | A | — | — |
| 4H9R | Complex structure 5 of DAXX(E225A)/H3.3(SUB5,G90A)/H4 | x-ray diffraction | A | — | — |
| 4H9S | Complex structure 6 of DAXX/H3.3(sub7)/H4 | x-ray diffraction | A, B | — | — |
| 4H9S | Complex structure 6 of DAXX/H3.3(SUB7)/H4 | x-ray diffraction | A, B | — | — |
| 4HGA | Structure of the variant histone H3.3-H4 heterodimer in complex with its chaperone DAXX | x-ray diffraction | B | — | — |
| 4HGA | Structure of the variant histone H3.3-H4 heterodimer in complex with its chaperone daxx | x-ray diffraction | B | — | — |
| 4N4I | Crystal structure of the Bromo-PWWP of the mouse zinc finger MYND-type containing 11 isoform alpha… | x-ray diffraction | B | — | — |
| 4N4I | Crystal structure of the bromo-pwwp of the mouse zinc finger mynd-type containing 11 isoform alpha… | x-ray diffraction | B | — | — |
| 4QQ4 | CW-type zinc finger of MORC3 in complex with the amino terminus of histone H3 | x-ray diffraction | C, D | — | — |
| 4QQ4 | Cw-type zinc finger of MORC3 in complex with the amino terminus of histone H3 | x-ray diffraction | C, D | — | — |
| 4TMP | Crystal structure of AF9 YEATS bound to H3K9ac peptide | x-ray diffraction | B, D | — | — |
| 4TMP | Crystal structure of AF9 yeats bound to H3K9AC peptide | x-ray diffraction | B, D | — | — |
| 4U7T | Crystal structure of DNMT3A-DNMT3L in complex with histone H3 | x-ray diffraction | F, G | — | — |
| 4U7T | Crystal structure of DNMT3A-DNMT3L in complex with histone H3 | x-ray diffraction | F, G | — | — |
| 4W5A | Complex structure of ATRX ADD bound to H3K9me3S10ph peptide | x-ray diffraction | C, D, F | — | — |
| 4W5A | Complex structure of atrx add bound to H3K9ME3S10PH peptide | x-ray diffraction | C, D, F | — | — |
71 records more on the page itself.
Ligands
- SO4 · Sulfate ion · in 4 records
- MN · Manganese (II) ion · in 3 records
- CL · Chloride ion · in 2 records
- OGA · N-oxalylglycine · in 2 records
- QVR · (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol · in 2 records
- SCN · Thiocyanate ion · in 2 records
- ZN · Zinc ion · in 2 records
- ACE · Acetyl group · in 1 record
- PO4 · Phosphate ion · in 1 record
- PR · Praseodymium ion · in 1 record
Experiment against prediction
- 3AV2 chain A against the predicted model P84243: TM-score 0.99, RMSD 0.35 Å
- 3AV2 chain A against the predicted model P84243: TM-score 0.99, RMSD 0.35 Å
- 5B33 chain A against the predicted model P84243: TM-score 0.99, RMSD 0.38 Å
- 5B33 chain A against the predicted model P84243: TM-score 0.99, RMSD 0.38 Å
- 5X7X chain A against the predicted model P84243: TM-score 0.99, RMSD 0.39 Å
- 5X7X chain E against the predicted model P84243: TM-score 0.99, RMSD 0.43 Å
- 7A08 chain d against the predicted model P84243: TM-score 0.99, RMSD 0.41 Å
- 5B32 chain A against the predicted model P84243: TM-score 0.99, RMSD 0.45 Å
- 5B32 chain A against the predicted model P84243: TM-score 0.99, RMSD 0.45 Å
- 9EOZ chain K against the predicted model P84243: TM-score 0.99, RMSD 0.45 Å
Elsewhere
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