UniProt P78330
Phosphoserine phosphatase (P78330)
Phosphoserine phosphatase (UniProt P78330), EC 3.1.3.3: 12 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P78330
- Protein
- Phosphoserine phosphatase
- EC
- 3.1.3.3
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 8 · 3 records with a druggable one
Structures
13 records of P78330 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1L8L | Molecular basis for the local confomational rearrangement of human phosphoserine phosphatase | x-ray diffraction | A, B | — | — |
| 1L8L | Molecular basis for the local confomational rearrangement of human phosphoserine phosphatase | x-ray diffraction | A, B | — | — |
| 1L8O | Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase | x-ray diffraction | A, B | — | — |
| 1L8O | Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase | x-ray diffraction | A, B | — | — |
| 1NNL | Crystal structure of Human Phosphoserine Phosphatase | x-ray diffraction | A, B | — | — |
| 1NNL | Crystal structure of human phosphoserine phosphatase | x-ray diffraction | A, B | — | — |
| 6HYJ | PSPH Human phosphoserine phosphatase | x-ray diffraction | A, B | CA | — |
| 6HYJ | Psph human phosphoserine phosphatase | x-ray diffraction | A, B | CA | — |
| 6HYY | Human phosphoserine phosphatase with serine and phosphate | x-ray diffraction | A, B | PO4, MG, SER, CA | 3 (best 0.73) |
| 6HYY | Human phosphoserine phosphatase with serine and phosphate | x-ray diffraction | A, B | PO4, MG, CA | — |
| 6Q6J | Human phosphoserine phosphatase with substrate analogue homo-cysteic acid | x-ray diffraction | A, B | CA, HJT, CL | 4 (best 0.75) |
| 6Q6J | Human phosphoserine phosphatase with substrate analogue homo-cysteic acid | x-ray diffraction | A, B | CA, CL | — |
| P78330 | AlphaFold monomer V2.0 prediction for phosphoserine phosphatase (P78330) | predicted | A | — | 1 (best 0.68) |
Ligands
Experiment against prediction
- 1NNL chain B against the predicted model P78330: TM-score 0.99, RMSD 0.57 Å
- 1NNL chain B against the predicted model P78330: TM-score 0.99, RMSD 0.57 Å
- 1NNL chain A against the predicted model P78330: TM-score 0.99, RMSD 0.60 Å
- 1NNL chain A against the predicted model P78330: TM-score 0.99, RMSD 0.60 Å
- 1L8L chain A against the predicted model P78330: TM-score 0.97, RMSD 1.09 Å
- 1L8L chain A against the predicted model P78330: TM-score 0.97, RMSD 1.09 Å
- 6Q6J chain B against the predicted model P78330: TM-score 0.97, RMSD 1.35 Å
- 6HYY chain B against the predicted model P78330: TM-score 0.97, RMSD 1.26 Å
- 6HYY chain B against the predicted model P78330: TM-score 0.97, RMSD 1.26 Å
- 6Q6J chain A against the predicted model P78330: TM-score 0.96, RMSD 1.45 Å
Elsewhere
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