UniProt P69905
Hemoglobin subunit alpha (P69905)
Hemoglobin subunit alpha (UniProt P69905): 577 experimental structures and 1 predicted model on GenesisL1, 40 ligands bound, 258 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P69905
- Protein
- Hemoglobin subunit alpha
- Experimental structures
- 577
- Predicted models
- 1
- Ligands
- 40
- Pockets
- 258 · 40 records with a druggable one
Structures
578 records of P69905 in the MolNFT archive: 577 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1A00 | Hemoglobin (val BETA1 met, TRP BETA37 tyr) mutant | x-ray diffraction | A, C | — | — |
| 1A00 | Hemoglobin (val BETA1 met, TRP BETA37 tyr) mutant | x-ray diffraction | A, C | — | — |
| 1A01 | Hemoglobin (val BETA1 met, TRP BETA37 ala) mutant | x-ray diffraction | A, C | — | — |
| 1A01 | Hemoglobin (val BETA1 met, TRP BETA37 ala) mutant | x-ray diffraction | A, C | — | — |
| 1A0U | Hemoglobin (val BETA1 met) mutant | x-ray diffraction | A, C | — | — |
| 1A0U | Hemoglobin (val BETA1 met) mutant | x-ray diffraction | A, C | — | — |
| 1A0Z | Hemoglobin (val BETA1 met) mutant | x-ray diffraction | A, C | — | — |
| 1A0Z | Hemoglobin (val BETA1 met) mutant | x-ray diffraction | A, C | — | — |
| 1A3N | Deoxy human hemoglobin | x-ray diffraction | A, C | — | — |
| 1A3N | 1a3n | x-ray diffraction | A, C | — | — |
| 1A3O | Artificial mutant (alpha Y42H) of deoxy hemoglobin | x-ray diffraction | A, C | — | — |
| 1A3O | Artificial mutant (alpha Y42H) of deoxy hemoglobin | x-ray diffraction | A, C | — | — |
| 1A9W | Human embryonic gower II carbonmonoxy hemoglobin | x-ray diffraction | A, C | — | — |
| 1A9W | Human embryonic gower II carbonmonoxy hemoglobin | x-ray diffraction | A, C | — | — |
| 1ABW | Deoxy RHB1.1 (recombinant hemoglobin) | x-ray diffraction | A | — | — |
| 1ABW | Deoxy RHB1.1 (recombinant hemoglobin) | x-ray diffraction | A | — | — |
| 1ABY | Cyanomet RHB1.1 (recombinant hemoglobin) | x-ray diffraction | A | — | — |
| 1ABY | Cyanomet RHB1.1 (recombinant hemoglobin) | x-ray diffraction | A | — | — |
| 1AJ9 | R-state human carbonmonoxyhemoglobin alpha-A53S | x-ray diffraction | A | — | — |
| 1AJ9 | R-state human carbonmonoxyhemoglobin alpha-A53S | x-ray diffraction | A | — | — |
| 1B86 | Human deoxyhaemoglobin-2,3-diphosphoglycerate complex | x-ray diffraction | A, C | — | — |
| 1B86 | Human deoxyhaemoglobin-2,3-diphosphoglycerate complex | x-ray diffraction | A, C | — | — |
| 1BAB | Hemoglobin thionville: an alpha-chain variant with a substitution of a glutamate for valine at na-1… | x-ray diffraction | A, C | — | — |
| 1BAB | Hemoglobin thionville: an alpha-chain variant with a substitution of a glutamate for valine at na-1… | x-ray diffraction | A, C | — | — |
| 1BBB | A third quaternary structure of human hemoglobin a at 1.7-ångströms resolution | x-ray diffraction | A, C | — | — |
| 1BBB | A third quaternary structure of human hemoglobin a at 1.7-ångströms resolution | x-ray diffraction | A, C | — | — |
| 1BIJ | Crosslinked, deoxy human hemoglobin a | x-ray diffraction | A, C | — | — |
| 1BIJ | Crosslinked, deoxy human hemoglobin a | x-ray diffraction | A, C | — | — |
| 1BUW | Crystal structure of S-nitroso-nitrosyl human hemoglobin a | x-ray diffraction | A, C | — | — |
| 1BUW | Crystal structure of S-nitroso-nitrosyl human hemoglobin a | x-ray diffraction | A, C | — | — |
| 1BZ0 | Hemoglobin a (human, deoxy, high salt) | x-ray diffraction | A, C | — | — |
| 1BZ0 | Hemoglobin a (human, deoxy, high salt) | x-ray diffraction | A, C | — | — |
| 1BZ1 | Hemoglobin (alpha + met) variant | x-ray diffraction | A, C | — | — |
| 1BZ1 | Hemoglobin (alpha + met) variant | x-ray diffraction | A, C | — | — |
| 1BZZ | Hemoglobin (alpha V1M) mutant | x-ray diffraction | A, C | — | — |
| 1BZZ | Hemoglobin (alpha V1M) mutant | x-ray diffraction | A, C | — | — |
| 1C7B | Deoxy RHB1.0 (recombinant hemoglobin) | x-ray diffraction | A, C | — | — |
| 1C7B | Deoxy RHB1.0 (recombinant hemoglobin) | x-ray diffraction | A, C | — | — |
| 1C7C | Deoxy RHB1.1 (recombinant hemoglobin) | x-ray diffraction | A | — | — |
| 1C7C | Deoxy RHB1.1 (recombinant hemoglobin) | x-ray diffraction | A | — | — |
| 1C7D | Deoxy RHB1.2 (recombinant hemoglobin) | x-ray diffraction | A | — | — |
| 1C7D | Deoxy RHB1.2 (recombinant hemoglobin) | x-ray diffraction | A | — | — |
| 1CLS | Cross-linked human hemoglobin deoxy | x-ray diffraction | A, C | — | — |
| 1CLS | Cross-linked human hemoglobin deoxy | x-ray diffraction | A, C | — | — |
| 1CMY | The mutation BETA99 asp-tyr stabilizes Y-a new, composite quaternary state of human hemoglobin | x-ray diffraction | A, C | — | — |
| 1CMY | The mutation BETA99 asp-tyr stabilizes Y-a new, composite quaternary state of human hemoglobin | x-ray diffraction | A, C | — | — |
| 1COH | Structure of haemoglobin in the deoxy quaternary state with ligand bound at the alpha haems | x-ray diffraction | A, C | — | — |
| 1COH | Structure of haemoglobin in the deoxy quaternary state with ligand bound at the alpha haems | x-ray diffraction | A, C | — | — |
| 1DKE | Ni beta heme human hemoglobin | x-ray diffraction | A, C | — | — |
| 1DKE | Ni beta heme human hemoglobin | x-ray diffraction | A, C | — | — |
| 1DXT | High-resolution X-ray study of deoxy recombinant human hemoglobins synthesized from beta-globins… | x-ray diffraction | A, C | HEM | — |
| 1DXT | High-resolution X-ray study of deoxy recombinant human hemoglobins synthesized from beta-globins… | x-ray diffraction | A, C | HEM | — |
| 1DXU | High-resolution X-ray study of deoxy recombinant human hemoglobins synthesized from beta-globins… | x-ray diffraction | A, C | — | — |
| 1DXU | High-resolution X-ray study of deoxy recombinant human hemoglobins synthesized from beta-globins… | x-ray diffraction | A, C | — | — |
| 1DXV | High-resolution X-ray study of deoxy recombinant human hemoglobins synthesized from beta-globins… | x-ray diffraction | A, C | — | — |
| 1DXV | High-resolution X-ray study of deoxy recombinant human hemoglobins synthesized from beta-globins… | x-ray diffraction | A, C | — | — |
| 1FDH | Structure of human foetal deoxyhaemoglobin | x-ray diffraction | A, B | — | — |
| 1FDH | Structure of human foetal deoxyhaemoglobin | x-ray diffraction | A, B | — | — |
| 1FN3 | Crystal structure of nickel reconstituted hemoglobin-a case for permanent, T-state hemoglobin | x-ray diffraction | A, C | — | — |
| 1FN3 | Crystal structure of nickel reconstituted hemoglobin-a case for permanent, T-state hemoglobin | x-ray diffraction | A, C | — | — |
518 records more on the page itself.
Ligands
- HEM · Protoporphyrin IX containing Fe · in 119 records
- CMO · Carbon monoxide · in 59 records
- HNI · Protoporphyrin IX containing ni(ii) · in 13 records
- OXY · Oxygen molecule · in 9 records
- PO4 · Phosphate ion · in 6 records
- O4B · 1,4,7,10,13,16-hexaoxacyclooctadecane · in 4 records
- S1P · (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate · in 4 records
- PEM · 2-[P-[2-P-chlorobenzamido)ethyl]phenoxy]-2-methylpropionic acid · in 3 records
- 7SJ · 2-methoxy-5-({2-[1-(propan-2-yl)-1H-pyrazol-5-yl]pyridin-3-yl}methoxy)pyridine-4-carbaldehyde · in 2 records
- 86M · 5-[(imidazo[1,2-a]pyridin-8-yl)methoxy]-2-methoxypyridine-4-carbaldehyde · in 2 records
- GJ1 · {6-[(4-methoxy-2-methylphenoxy)methyl]pyridin-2-yl}methanol · in 2 records
- H2S · Hydrosulfuric acid · in 2 records
- KOH · 3-[2-chloranyl-4-(1~{H}-imidazol-2-yl)phenoxy]propanoic acid · in 2 records
- MBN · Toluene · in 2 records
- MWC · dihydroxy[(5-methylfuran-2-yl)methoxy]amine · in 2 records
- N1X · (2S)-2-(5-methylfuran-2-yl)oxane · in 2 records
- SO4 · Sulfate ion · in 2 records
- V1M · methyl 5-[(4-methoxy-2-methylphenoxy)methyl]pyridine-2-carboxylate · in 2 records
- V2D · methyl 2-[(3-hydroxy-2-methylphenoxy)methyl]pyridine-3-carboxylate · in 2 records
- 5JN · 2-(nitrooxy)ethyl 2-(4-{2-[(3,5-dimethylphenyl)amino]-2-oxoethyl}phenoxy)-2-methylpropanoate · in 1 record
- 5L7 · 2-methyl-3-({2-[1-(propan-2-yl)-1H-pyrazol-5-yl]pyridin-3-yl}methoxy)phenol · in 1 record
- 8MV · (5-formylfuran-2-yl)methyl acetate · in 1 record
- E0J · 2-[(4-methoxy-2-methylphenoxy)methyl]pyridine · in 1 record
- FRU · beta-D-fructofuranose · in 1 record
- FUX · 5-hydroxymethyl-furfural · in 1 record
- GLC · alpha-D-glucopyranose · in 1 record
- K7M · (2R)-N-hydroxy-1-phenylpropan-2-amine · in 1 record
- MW0 · (5-methylfuran-2-yl)methanol · in 1 record
- N2Q · (5P)-5-(5-methylfuran-2-yl)-1H-pyrazole · in 1 record
- NO · Nitric oxide · in 1 record
Experiment against prediction
- 1GLI chain A against the predicted model P69905: TM-score 1.00, RMSD 0.23 Å
- 1O1K chain A against the predicted model P69905: TM-score 1.00, RMSD 0.24 Å
- 1RQ3 chain A against the predicted model P69905: TM-score 1.00, RMSD 0.25 Å
- 1HBB chain A against the predicted model P69905: TM-score 1.00, RMSD 0.26 Å
- 1J7W chain A against the predicted model P69905: TM-score 1.00, RMSD 0.26 Å
- 1A0U chain A against the predicted model P69905: TM-score 1.00, RMSD 0.27 Å
- 1XXT chain A against the predicted model P69905: TM-score 1.00, RMSD 0.27 Å
- 1HGB chain A against the predicted model P69905: TM-score 1.00, RMSD 0.27 Å
- 1XY0 chain A against the predicted model P69905: TM-score 1.00, RMSD 0.27 Å
- 6KAE chain G against the predicted model P69905: TM-score 1.00, RMSD 0.27 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.