UniProt P62694
Exoglucanase 1 (P62694)
Exoglucanase 1 (UniProt P62694), EC 3.2.1.91: 75 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P62694
- Protein
- Exoglucanase 1
- EC
- 3.2.1.91
- Experimental structures
- 75
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 5 · 3 records with a druggable one
Structures
76 records of P62694 in the MolNFT archive: 75 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AZ6 | Three-dimensional structures of three engineered cellulose-binding domains of cellobiohydrolase I… | solution nmr | A | — | — |
| 1AZ6 | Three-dimensional structures of three engineered cellulose-binding domains of cellobiohydrolase I… | solution nmr | A | — | — |
| 1AZH | Three-dimensional structures of three engineered cellulose-binding domains of cellobiohydrolase I… | solution nmr | A | — | — |
| 1AZH | Three-dimensional structures of three engineered cellulose-binding domains of cellobiohydrolase I… | solution nmr | A | — | — |
| 1AZJ | Three-dimensional structures of three engineered cellulose-binding domains of cellobiohydrolase I… | solution nmr | A | — | — |
| 1AZJ | Three-dimensional structures of three engineered cellulose-binding domains of cellobiohydrolase I… | solution nmr | A | — | — |
| 1AZK | Three-dimensional structures of three engineered cellulose-binding domains of cellobiohydrolase I… | solution nmr | A | — | — |
| 1AZK | Three-dimensional structures of three engineered cellulose-binding domains of cellobiohydrolase I… | solution nmr | A | — | — |
| 1CBH | Determination of the three-dimensional structure of the C-terminal domain of cellobiohydrolase I… | solution nmr | A | — | — |
| 1CBH | Determination of the three-dimensional structure of the C-terminal domain of cellobiohydrolase I… | solution nmr | A | — | — |
| 1DY4 | CBH1 in complex with S-propranolol | x-ray diffraction | A | — | — |
| 1DY4 | CBH1 in complex with S-propranolol | x-ray diffraction | A | — | — |
| 1EGN | Cellobiohydrolase CEL7A (E223S, A224H, L225V, T226A, D262G) mutant | x-ray diffraction | A | — | — |
| 1EGN | Cellobiohydrolase CEL7A (E223S, A224H, L225V, T226A, D262G) mutant | x-ray diffraction | A | — | — |
| 1Q2B | Cellobiohydrolase CEL7A with disulphide bridge added across exo-loop by mutations D241C and D249C | x-ray diffraction | A | — | — |
| 1Q2B | Cellobiohydrolase CEL7A with disulphide bridge added across exo-loop by mutations D241C and D249C | x-ray diffraction | A | — | — |
| 2CBH | Determination of the three-dimensional structure of the C-terminal domain of cellobiohydrolase I… | solution nmr | A | — | — |
| 2CBH | Determination of the three-dimensional structure of the C-terminal domain of cellobiohydrolase I… | solution nmr | A | — | — |
| 2CEL | Active-site mutant E212Q determined at pH 6.0 with no ligand bound in the active site | x-ray diffraction | A, B | — | — |
| 2CEL | Active-site mutant E212Q determined at pH 6.0 with no ligand bound in the active site | x-ray diffraction | A, B | — | — |
| 2MWJ | Solution structure of Family 1 Carbohydrate-Binding Module from Trichoderma reesei Cel7A with… | solution nmr | A | — | — |
| 2MWJ | Solution structure of family 1 carbohydrate-binding module from trichoderma reesei CEL7A with… | solution nmr | A | — | — |
| 2MWK | Family 1 Carbohydrate-Binding Module from Trichoderma reesei Cel7A with O-mannose residues at Thr1… | solution nmr | A | — | — |
| 2MWK | Family 1 carbohydrate-binding module from trichoderma reesei CEL7A with O-mannose residues at THR1… | solution nmr | A | — | — |
| 2V3I | Hypocrea jecorina Cel7A in complex with (R)-dihydroxy-phenanthrenolol | x-ray diffraction | A | — | — |
| 2V3I | Hypocrea jecorina CEL7A in complex with (R)-dihydroxy-phenanthrenolol | x-ray diffraction | A | — | — |
| 2V3R | Hypocrea jecorina Cel7A in complex with (S)-dihydroxy-phenanthrenolol | x-ray diffraction | A | — | — |
| 2V3R | Hypocrea jecorina CEL7A in complex with (S)-dihydroxy-phenanthrenolol | x-ray diffraction | A | — | — |
| 4C4C | Michaelis complex of Hypocrea jecorina CEL7A E217Q mutant with cellononaose spanning the active site | x-ray diffraction | A | — | — |
| 4C4C | Michaelis complex of hypocrea jecorina CEL7A E217Q mutant with cellononaose spanning the active site | x-ray diffraction | A | — | — |
| 4C4D | Covalent glycosyl-enzyme intermediate of Hypocrea jecorina Cel7a E217Q mutant trapped using… | x-ray diffraction | A | — | — |
| 4C4D | Covalent glycosyl-enzyme intermediate of hypocrea jecorina CEL7A E217Q mutant trapped using… | x-ray diffraction | A | — | — |
| 4CEL | Active-site mutant D214N determined at pH 6.0 with no ligand bound in the active site | x-ray diffraction | A, B | — | — |
| 4CEL | Active-site mutant D214N determined at pH 6.0 with no ligand bound in the active site | x-ray diffraction | A, B | — | — |
| 4D5I | Hypocrea jecorina cellobiohydrolase Cel7A E212Q soaked with xylotriose. | x-ray diffraction | A | — | — |
| 4D5I | Hypocrea jecorina cellobiohydrolase CEL7A E212Q soaked with xylotriose. | x-ray diffraction | A | — | — |
| 4D5J | Hypocrea jecorina cellobiohydrolase Cel7A E217Q soaked with xylotriose. | x-ray diffraction | A | — | — |
| 4D5J | Hypocrea jecorina cellobiohydrolase CEL7A E217Q soaked with xylotriose. | x-ray diffraction | A | — | — |
| 4D5O | Hypocrea jecorina cellobiohydrolase Cel7A E212Q soaked with xylopentaose. | x-ray diffraction | A | — | — |
| 4D5O | Hypocrea jecorina cellobiohydrolase CEL7A E212Q soaked with xylopentaose. | x-ray diffraction | A | — | — |
| 4D5P | Hypocrea jecorina cellobiohydrolase Cel7A E217Q soaked with xylopentaose. | x-ray diffraction | A | — | — |
| 4D5P | Hypocrea jecorina cellobiohydrolase CEL7A E217Q soaked with xylopentaose. | x-ray diffraction | A | — | — |
| 4D5Q | Hypocrea jecorina Cel7A (wild type) soaked with xylopentaose. | x-ray diffraction | A | — | — |
| 4D5Q | Hypocrea jecorina CEL7A (wild type) soaked with xylopentaose. | x-ray diffraction | A | — | — |
| 4D5V | Hypocrea jecorina cellobiohydrolase Cel7A E217Q soaked with xylotetraose. | x-ray diffraction | A | — | — |
| 4D5V | Hypocrea jecorina cellobiohydrolase CEL7A E217Q soaked with xylotetraose. | x-ray diffraction | A | — | — |
| 4P1H | Crystal structure of wild type Hypocrea jecorina Cel7a in a monoclinic crystal form | x-ray diffraction | A | — | — |
| 4P1H | Crystal structure of wild type hypocrea jecorina CEL7A in a monoclinic crystal form | x-ray diffraction | A | — | — |
| 4P1J | Crystal structure of wild type Hypocrea jecorina Cel7a in a hexagonal crystal form | x-ray diffraction | A | — | — |
| 4P1J | Crystal structure of wild type hypocrea jecorina CEL7A in a hexagonal crystal form | x-ray diffraction | A | — | — |
| 4UWT | Hypocrea jecorina Cel7A E212Q mutant in complex with p-nitrophenyl cellobioside | x-ray diffraction | A | — | — |
| 4UWT | Hypocrea jecorina CEL7A E212Q mutant in complex with P-nitrophenyl cellobioside | x-ray diffraction | A | — | — |
| 4V0Z | o-nitrophenyl Cellobioside as an Active Site Probe for Family 7 Cellobiohydrolases | x-ray diffraction | A | — | — |
| 4V0Z | O-nitrophenyl cellobioside as an active site probe for family 7 cellobiohydrolases | x-ray diffraction | A | — | — |
| 5OA5 | Cellobiohydrolase I (CEL7A) from hypocrea jecorina with improved thermal stability | x-ray diffraction | A, B | NAG | 3 (best 0.82) |
| 5OA5 | Cellobiohydrolase I (CEL7A) from hypocrea jecorina with improved thermal stability | x-ray diffraction | A, B | NAG | — |
| 5X34 | Solution structure of the family 1 carbohydrate-binding module, unglycosylated form | solution nmr | A | — | — |
| 5X35 | Solution structure of the Family 1 carbohydrate-binding module with mannosylated Thr1 | solution nmr | A | MAN | — |
| 5X35 | Solution structure of the family 1 carbohydrate-binding module with mannosylated THR1 | solution nmr | A | MAN | — |
| 5X36 | Solution structure of the family 1 carbohydrate-binding module with mannosylated SER3 | solution nmr | A | MAN | — |
16 records more on the page itself.
Ligands
- MAN · alpha-D-mannopyranose · in 10 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 8 records
- CO · Cobalt (II) ion · in 6 records
- BGC · beta-D-glucopyranose · in 5 records
- GAL · beta-D-galactopyranose · in 4 records
- NPO · P-nitrophenol · in 4 records
- F9B · 2-[[(2~{S})-3-naphthalen-1-yloxy-2-oxidanyl-propyl]amino]propane-1,3-diol · in 2 records
Experiment against prediction
- 4D5J chain A against the predicted model P62694: TM-score 1.00, RMSD 0.32 Å
- 4D5J chain A against the predicted model P62694: TM-score 1.00, RMSD 0.32 Å
- 4D5O chain A against the predicted model P62694: TM-score 1.00, RMSD 0.32 Å
- 4D5O chain A against the predicted model P62694: TM-score 1.00, RMSD 0.32 Å
- 1DY4 chain A against the predicted model P62694: TM-score 1.00, RMSD 0.33 Å
- 1DY4 chain A against the predicted model P62694: TM-score 1.00, RMSD 0.33 Å
- 2V3R chain A against the predicted model P62694: TM-score 1.00, RMSD 0.33 Å
- 2V3R chain A against the predicted model P62694: TM-score 1.00, RMSD 0.33 Å
- 2V3I chain A against the predicted model P62694: TM-score 1.00, RMSD 0.33 Å
- 2V3I chain A against the predicted model P62694: TM-score 1.00, RMSD 0.33 Å
Elsewhere
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