UniProt P61011
Signal recognition particle 54 kDa protein (P61011)
Signal recognition particle 54 kDa protein (UniProt P61011), EC 3.6.5.-: 14 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 38 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P61011
- Protein
- Signal recognition particle 54 kDa protein
- EC
- 3.6.5.-
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 38 · 3 records with a druggable one
Structures
15 records of P61011 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1MFQ | Crystal Structure Analysis of a Ternary S-Domain Complex of Human Signal Recognition Particle | x-ray diffraction | C | — | — |
| 1MFQ | Crystal structure analysis of a ternary S-domain complex of human signal recognition particle | x-ray diffraction | C | — | — |
| 1QB2 | Crystal structure of the conserved subdomain of human protein SRP54M at 2.1A resolution: evidence… | x-ray diffraction | A, B | — | — |
| 1QB2 | Crystal structure of the conserved subdomain of human protein SRP54M at 2.1A resolution: evidence… | x-ray diffraction | A, B | — | — |
| 5L3Q | Structure of the GTPase heterodimer of human SRP54 and SRalpha | x-ray diffraction | A, C | SO4, GNP, MG, AMP | — |
| 5L3Q | Structure of the GTPase heterodimer of human SRP54 and sralpha | x-ray diffraction | A, C | SO4, GNP, MG, AMP | — |
| 6Y2Z | Ng domain of human SRP54 | x-ray diffraction | A, B | PO4, MG | — |
| 6Y30 | NG domain of human SRP54 T115A mutant | x-ray diffraction | A, B | — | — |
| 6Y30 | Ng domain of human SRP54 T115A mutant | x-ray diffraction | A, B | — | — |
| 6Y31 | NG domain of human SRP54 T117 deletion mutant | x-ray diffraction | A, B, C, D | — | 17 (best 0.58) |
| 6Y31 | Ng domain of human SRP54 T117 deletion mutant | x-ray diffraction | A, B, C, D | — | — |
| 6Y32 | Structure of the GTPase heterodimer of human SRP54 and SRalpha | x-ray diffraction | A, C, E, G | GNP, MG, SO4 | 16 (best 0.87) |
| 6Y32 | Structure of the GTPase heterodimer of human SRP54 and sralpha | x-ray diffraction | A, C, E, G | GNP, MG, SO4 | — |
| 7NFX | Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A | electron microscopy | x | GNP, MG | — |
| P61011 | AlphaFold monomer V2.0 prediction for signal recognition particle 54 kda protein (P61011) | predicted | A | — | 5 (best 0.78) |
Ligands
Experiment against prediction
- 5L3Q chain A against the predicted model P61011: TM-score 0.95, RMSD 1.57 Å
- 5L3Q chain A against the predicted model P61011: TM-score 0.95, RMSD 1.57 Å
- 6Y32 chain A against the predicted model P61011: TM-score 0.94, RMSD 1.81 Å
- 6Y32 chain A against the predicted model P61011: TM-score 0.94, RMSD 1.81 Å
- 6Y32 chain E against the predicted model P61011: TM-score 0.94, RMSD 1.87 Å
- 6Y32 chain G against the predicted model P61011: TM-score 0.94, RMSD 1.90 Å
- 6Y32 chain G against the predicted model P61011: TM-score 0.94, RMSD 1.90 Å
- 6Y32 chain C against the predicted model P61011: TM-score 0.93, RMSD 1.94 Å
- 6Y32 chain C against the predicted model P61011: TM-score 0.93, RMSD 1.94 Å
- 6Y30 chain A against the predicted model P61011: TM-score 0.93, RMSD 1.84 Å
Elsewhere
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