MolNFT v1 · #170297 · protein
Ng domain of human SRP54 T115A mutant
6Y30 · Signal recognition particle 54 kda protein: “Ng domain of human SRP54 T115A mutant”. X-ray diffraction, 12 pockets (best druggability 0.60). MolNFT v1 #170297 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6Y30
- Type
- protein
- Length
- 582 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Signal recognition particle 54 kda protein
- UniProt
- P61011
- Pockets
- 12 · best druggability 0.60
Structure
x-ray diffraction · 2 distinct chains · 51% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Signal recognition particle 54 kda protein | protein | 298 | 51% helix, 14% strand | P61011 |
| B | Signal recognition particle 54 kda protein | protein | 284 | 50% helix, 13% strand | P61011 |
Pockets
12 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 493 | 0.60 | 0.75 | 55 | empty |
| 2 | 114 | 0.44 | 0.77 | 21 | empty |
| 3 | 93 | 0.38 | 0.75 | 25 | empty |
| 4 | 76 | 0.37 | 0.77 | 12 | empty |
| 5 | 87 | 0.37 | 0.75 | 25 | empty |
Interfaces
1 interface between chains.
- A–B · 525 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P61011
- Elsewhere: RCSB PDB 6Y30 · PDBe 6Y30 · UniProt P61011
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