UniProt P61006
Ras-related protein Rab-8A (P61006)
Ras-related protein Rab-8A (UniProt P61006), EC 3.6.5.2: 32 experimental structures on GenesisL1, 4 ligands bound, 15 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P61006
- Protein
- Ras-related protein Rab-8A
- EC
- 3.6.5.2
- Experimental structures
- 32
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 15 · 4 records with a druggable one
Structures
32 records of P61006 in the MolNFT archive: 32 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3QBT | Crystal structure of OCRL1 540-678 in complex with Rab8a:GppNHp | x-ray diffraction | A, C, E, G | — | — |
| 3QBT | Crystal structure of OCRL1 540-678 in complex with RAB8A:GPPNHP | x-ray diffraction | A, C, E, G | — | — |
| 3TNF | LidA from Legionella in complex with active Rab8a | x-ray diffraction | A | — | — |
| 3TNF | Lida from legionella in complex with active RAB8A | x-ray diffraction | A | — | — |
| 4LHV | Crystal structure of Rab8 in its inactive GDP-bound form | x-ray diffraction | A, B, C, D, E | — | — |
| 4LHV | Crystal structure of RAB8 in its inactive GDP-bound form | x-ray diffraction | A, B, C, D, E | — | — |
| 4LHW | Crystal structure of Rab8 in its active GppNHp-bound form | x-ray diffraction | A, B, C, D, E | — | — |
| 4LHW | Crystal structure of RAB8 in its active gppnhp-bound form | x-ray diffraction | A, B, C, D, E | — | — |
| 4LHX | Crystal structure of nucleotide-free Rab8:Rabin8 | x-ray diffraction | A, B | — | — |
| 4LHX | Crystal structure of nucleotide-free RAB8:RABIN8 | x-ray diffraction | A, B | — | — |
| 4LHY | Crystal structure of GDP-bound Rab8:Rabin8 | x-ray diffraction | A, B | — | — |
| 4LHY | Crystal structure of GDP-bound RAB8:RABIN8 | x-ray diffraction | A, B | — | — |
| 4LHZ | Crystal structure of GTP-bound Rab8:Rabin8 | x-ray diffraction | A, B | — | — |
| 4LHZ | Crystal structure of GTP-bound RAB8:RABIN8 | x-ray diffraction | A, B | — | — |
| 4LI0 | Crystal structure of GDP-bound Rab8:GRAB | x-ray diffraction | A, B | — | — |
| 4LI0 | Crystal structure of GDP-bound RAB8:GRAB | x-ray diffraction | A, B | — | — |
| 5SZI | Structure of human Rab8a in complex with the bMERB domain of Mical-cL | x-ray diffraction | A | GNP, MG | 2 (best 0.75) |
| 5SZI | Structure of human RAB8A in complex with the bmerb domain of mical-cl | x-ray diffraction | A | GNP, MG | — |
| 6RIR | Crystal structure of phosphorylated Rab8a in complex with the Rab-binding domain of RILPL2 | x-ray diffraction | A, B | GTP, MG | — |
| 6RIR | Crystal structure of phosphorylated RAB8A in complex with the rab- binding domain of RILPL2 | x-ray diffraction | A, B | GTP, MG | — |
| 6SQ2 | Structure of a phosphomimetic switch 2 variant of Rab8a in complex with the phospho-Rab binding… | x-ray diffraction | A, B | GTP, MG | 4 (best 0.63) |
| 6SQ2 | Structure of a phosphomimetic switch 2 variant of RAB8A in complex with the phospho-rab binding… | x-ray diffraction | A, B | GTP, MG | — |
| 6STF | Human RAB8A phosphorylated at SER111 in complex with GDP | x-ray diffraction | A, B, C, D, E | GDP, MG | — |
| 6STG | Human RAB8A phosphorylated at SER111 in complex with gppnp | x-ray diffraction | A, B | GNP, MG | — |
| 6WHE | Structure of phosphomimetic RAB8A GTPase (T72E) in the GTP-bound state | x-ray diffraction | A, B | GTP, MG | — |
| 6ZSI | The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members. | x-ray diffraction | A, B | GNP, MG | 5 (best 0.68) |
| 6ZSI | The mechanism of activation of the actin binding protein EHBP1 by RAB8 family members. | x-ray diffraction | A, B | GNP, MG | — |
| 6ZSJ | The mechanism of activation of the actin binding protein EHBP1 by RAB8 family members. | x-ray diffraction | A, B | GNP, MG | — |
| 7BWT | Sopd-RAB8 complex structure | x-ray diffraction | B | GDP, MG | — |
| 7LWB | Crystal structure of phospho-RAB8A with the RH2 domain (117-165) of RILPL2 | x-ray diffraction | A | GTP, MG | — |
| 9IKQ | Crystal structure of OPTN LZD in complex with GTP-bound Rab8a(Q67L) | x-ray diffraction | A, B | GTP, MG | 4 (best 0.62) |
| P61006 | AlphaFold monomer V2.0 prediction for RAS-related protein rab-8A (P61006) | — | — | — |
Ligands
Elsewhere
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